JP2023553944A5 - - Google Patents

Info

Publication number
JP2023553944A5
JP2023553944A5 JP2023535390A JP2023535390A JP2023553944A5 JP 2023553944 A5 JP2023553944 A5 JP 2023553944A5 JP 2023535390 A JP2023535390 A JP 2023535390A JP 2023535390 A JP2023535390 A JP 2023535390A JP 2023553944 A5 JP2023553944 A5 JP 2023553944A5
Authority
JP
Japan
Prior art keywords
disease
registered trademark
inflammatory
composition according
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023535390A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023553944A (ja
Filing date
Publication date
Priority claimed from KR1020200171340A external-priority patent/KR20220081631A/ko
Application filed filed Critical
Publication of JP2023553944A publication Critical patent/JP2023553944A/ja
Publication of JP2023553944A5 publication Critical patent/JP2023553944A5/ja
Pending legal-status Critical Current

Links

JP2023535390A 2020-12-09 2021-12-09 炎症性疾患を予防または処置するためのピロロピリジン誘導体の新規な使用 Pending JP2023553944A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020200171340A KR20220081631A (ko) 2020-12-09 2020-12-09 염증성 질환의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도
KR10-2020-0171340 2020-12-09
PCT/IB2021/000857 WO2022123311A1 (en) 2020-12-09 2021-12-09 Novel use of pyrrolopyridine derivatives for preventing or treating inflammatory diseases

Publications (2)

Publication Number Publication Date
JP2023553944A JP2023553944A (ja) 2023-12-26
JP2023553944A5 true JP2023553944A5 (https=) 2024-11-01

Family

ID=81974509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023535390A Pending JP2023553944A (ja) 2020-12-09 2021-12-09 炎症性疾患を予防または処置するためのピロロピリジン誘導体の新規な使用

Country Status (7)

Country Link
US (2) US20220257605A1 (https=)
EP (1) EP4259153A4 (https=)
JP (1) JP2023553944A (https=)
KR (1) KR20220081631A (https=)
CN (1) CN116916929A (https=)
TW (1) TW202239403A (https=)
WO (1) WO2022123311A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3915985A4 (en) 2019-01-18 2022-09-28 Voronoi Co., Ltd. PYRROLOPYRIDE DERIVATIVE AND USE THEREOF FOR THE PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISEASES
KR20220081631A (ko) 2020-12-09 2022-06-16 보로노이 주식회사 염증성 질환의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도
WO2023220396A1 (en) * 2022-05-13 2023-11-16 Fresh Tracks Therapeutics, Inc. Methods of treatment using a dual specificity tyrosine-phosphorylation-regulated kinase 1a (dyrk1a) inhibitor
CN116270633A (zh) * 2023-03-03 2023-06-23 神经肌肉骨骼再生医学中心有限公司 马拉韦罗在制备治疗肌肉退行性疾病的药物中的用途
CN117244063A (zh) * 2023-05-24 2023-12-19 中国人民解放军空军军医大学 核酸z-b变构诱导物用于制备治疗结石疾病药物的应用
CN120754103B (zh) * 2025-09-09 2025-11-28 苏州大学 阿巴卡韦在制备类风湿性关节炎治疗药物中的应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2354140A1 (en) 2005-05-20 2011-08-10 Vertex Pharmaceuticals Incorporated Pyrrolopyridines useful as inhibitors of protein kinase
CN102127078A (zh) 2005-07-14 2011-07-20 安斯泰来制药株式会社 Janus激酶3的杂环类抑制剂
FR2912744B1 (fr) 2007-02-16 2012-09-07 Centre Nat Rech Scient Composes pyrrolo°2,3-b!pyridine,composes azaindoles utiles dans la synthese de ces composes pyrrolo°2,3-b!pyridine, leurs procedes de fabrication et leurs utilisations.
AU2008296479A1 (en) 2007-08-28 2009-03-12 Dana Farber Cancer Institute Amino substituted pyrimidine, pyrollopyridine and pyrazolopyrimidine derivatives useful as kinase inhibitors and in treating proliferative disorders and diseases associated with angiogenesis
AU2009238590A1 (en) 2008-04-22 2009-10-29 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
MX353308B (es) 2008-05-21 2018-01-08 Ariad Pharma Inc Derivados fosforosos como inhibidores de cinasa.
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
CN102712601A (zh) * 2009-11-12 2012-10-03 赛尔维他股份公司 化合物、其制备方法、药物组合物、化合物的用途、用于调节或调控丝氨酸/苏氨酸激酶的方法以及丝氨酸/苏氨酸激酶调节剂
WO2011090738A2 (en) 2009-12-29 2011-07-28 Dana-Farber Cancer Institute, Inc. Type ii raf kinase inhibitors
WO2012065935A1 (en) 2010-11-17 2012-05-24 F. Hoffmann-La Roche Ag Methods of treating tumors
US8791112B2 (en) 2011-03-30 2014-07-29 Arrien Pharmaceuticals Llc Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and pyrazolo [3, 4-B] pyridine derivatives as protein kinase inhibitors
WO2013043232A2 (en) 2011-04-08 2013-03-28 Afraxis, Inc. 8-ethyl-6-(aryl)pyrido [2,3-d]pyrimidin-7(8h) -ones for the treatment of nervous system disorders and cancer
TW201533043A (zh) 2013-04-18 2015-09-01 Lundbeck & Co As H 作爲lrrk2抑制劑的芳基吡咯并吡啶衍生化合物
KR20160106623A (ko) 2014-01-29 2016-09-12 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 화합물
RU2016134751A (ru) 2014-01-29 2018-03-02 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Соединения
MA39219B1 (fr) 2014-01-29 2018-11-30 Glaxosmithkline Ip Dev Ltd Nouveaux composés inhibiteurs de la kinase lrrk2 utilisés pour le traitement du parkinson, de l’alzheimer et de la sclérose latérale amyotrophique
TN2017000329A1 (en) 2015-01-28 2019-01-16 Bayer Pharma AG 4h-pyrrolo[3,2-c]pyridin-4-one derivatives
CN107801397B (zh) 2015-02-13 2021-07-30 达纳-法伯癌症研究所公司 Lrrk2抑制剂及其制备和使用方法
JP6530826B2 (ja) 2015-05-06 2019-06-12 プレキシコン インコーポレーテッドPlexxikon Inc. キナーゼを修飾する1h−ピロロ[2,3−b]ピリジン誘導体の合成
TWI703150B (zh) 2015-06-04 2020-09-01 美商庫拉腫瘤技術股份有限公司 用於抑制menin及mll蛋白之交互作用的方法及組合物
CA3021021A1 (en) 2016-04-15 2017-10-19 Felicitex Therapeutics, Inc. Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors
EP3587422A4 (en) 2017-02-22 2020-05-06 Daegu-Gyeongbuk Medical Innovation Foundation PYRROLOPYRIMIDINE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION WITH THIS COMPOUND AS AN ACTIVE SUBSTANCE FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE
CN110662745B (zh) 2017-03-23 2021-08-03 大邱庆北尖端医疗产业振兴财团 吡咯并吡啶衍生物、其制备方法、和用于预防或治疗蛋白激酶相关疾病的药物组合物
AU2020209789A1 (en) 2019-01-18 2021-09-16 Voronoi Co., Ltd. Pyrrolopyrimidine derivative, and pharmaceutical composition for preventing or treating protein kinase-related disease comprising same as active ingredient
EP3915985A4 (en) * 2019-01-18 2022-09-28 Voronoi Co., Ltd. PYRROLOPYRIDE DERIVATIVE AND USE THEREOF FOR THE PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISEASES
WO2020232332A1 (en) 2019-05-16 2020-11-19 Dana-Farber Cancer Institute, Inc. Pyrrolopyrimidine inhibitors of wild-type and mutant forms of lrrk2
WO2020235973A1 (ko) * 2019-05-22 2020-11-26 주식회사 보로노이 암의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도
KR20220081631A (ko) 2020-12-09 2022-06-16 보로노이 주식회사 염증성 질환의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도

Similar Documents

Publication Publication Date Title
JP2023553944A5 (https=)
US12194048B2 (en) Use of pyrrolopyridine derivatives for preventing or treating inflammatory diseases
US12551564B2 (en) IRAK degraders and uses thereof
TWI868528B (zh) Tyk2抑制劑之生產方法
TW202144343A (zh) Jak抑制劑化合物之結晶水合物
IL303458A (en) IRAK joints and their uses
CN107987075A (zh) 用于治疗癌症和免疫性和自身免疫性疾病的细胞凋亡诱导剂
IL284125B1 (en) History of quinoline use in the treatment of inflammatory diseases
US20230416242A1 (en) Double degraders and uses thereof
US12162884B2 (en) Solid forms of (R)-N-(2-(5-fluoropyridin-3-yl)-8-isopropylpyrazolo[1,5-a] [1,3,5]triazin-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine as aryl hydrocarbon receptor (AHR) inhibitors
EP3999185B1 (en) Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting
US20250099454A1 (en) Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a jak inhibitor
TW202304902A (zh) Jak抑制劑化合物之二鹽酸鹽之結晶形式
US20250170119A1 (en) Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
US20250215002A1 (en) Solid forms of tyk2 inhibitors and methods of use
EP3999184B1 (en) Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting
US20250032474A1 (en) Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
JP2025510859A (ja) Tyk2阻害剤製剤及びその作製方法
CN120737203A (zh) 抗cd38蛋白抗体及其制备方法和应用
WO2025147509A1 (en) Stat6 inhibitors and uses thereof
TW202529769A (zh) Tyk2抑制劑及其用途