JP2023552829A5 - - Google Patents

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Publication number
JP2023552829A5
JP2023552829A5 JP2023534951A JP2023534951A JP2023552829A5 JP 2023552829 A5 JP2023552829 A5 JP 2023552829A5 JP 2023534951 A JP2023534951 A JP 2023534951A JP 2023534951 A JP2023534951 A JP 2023534951A JP 2023552829 A5 JP2023552829 A5 JP 2023552829A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
acid sequence
cdr
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023534951A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023552829A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/062485 external-priority patent/WO2022125712A1/en
Publication of JP2023552829A publication Critical patent/JP2023552829A/ja
Publication of JP2023552829A5 publication Critical patent/JP2023552829A5/ja
Pending legal-status Critical Current

Links

JP2023534951A 2020-12-09 2021-12-08 免疫細胞機能を調節するための変異インターロイキン-10ポリペプチドの抗原結合分子との融合物 Pending JP2023552829A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063123387P 2020-12-09 2020-12-09
US63/123,387 2020-12-09
US202163169604P 2021-04-01 2021-04-01
US63/169,604 2021-04-01
PCT/US2021/062485 WO2022125712A1 (en) 2020-12-09 2021-12-08 Fusions of mutant interleukin-10 polypeptides with antigen binding molecules for modulating immune cell function

Publications (2)

Publication Number Publication Date
JP2023552829A JP2023552829A (ja) 2023-12-19
JP2023552829A5 true JP2023552829A5 (https=) 2024-12-17

Family

ID=81973973

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023534951A Pending JP2023552829A (ja) 2020-12-09 2021-12-08 免疫細胞機能を調節するための変異インターロイキン-10ポリペプチドの抗原結合分子との融合物

Country Status (8)

Country Link
US (1) US20240010695A1 (https=)
EP (1) EP4259645A4 (https=)
JP (1) JP2023552829A (https=)
KR (1) KR20230129423A (https=)
AU (1) AU2021396247A1 (https=)
CA (1) CA3204723A1 (https=)
TW (1) TW202237630A (https=)
WO (1) WO2022125712A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230112632A (ko) * 2020-10-23 2023-07-27 애셔 바이오테라퓨틱스, 인크. 면역 세포 기능을 조절하기 위한 cd8 항원 결합 분자와의 융합
IL308609A (en) 2021-05-19 2024-01-01 Asher Biotherapeutics Inc IL-21 polypeptides and target constructs
CN118206629B (zh) * 2022-12-16 2025-12-02 深圳莱芒生物科技有限公司 一种细胞因子白细胞介素10的突变体及其制备方法和应用
CN118240058A (zh) * 2022-12-24 2024-06-25 广东菲鹏制药股份有限公司 Il10突变体、融合蛋白和药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058950A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Improved interleukin 10
AU2003280315A1 (en) * 2002-11-14 2004-06-03 Maxygen, Inc. Conjugates of interleukin-10 and polymers
WO2015117930A1 (en) * 2014-02-06 2015-08-13 F. Hoffmann-La Roche Ag Interleukine 10 immunoconjugates
CR20200327A (es) * 2018-01-26 2020-11-05 Genentech Inc Proteínas de fusión fc il-22 y métodos de uso
JP2022512746A (ja) * 2018-10-19 2022-02-07 アンブルックス,インコーポレイテッド インターロイキン-10ポリペプチド複合体、その二量体、およびそれらの使用
SG11202102930YA (en) * 2018-11-08 2021-04-29 Synthorx Inc Interleukin 10 conjugates and uses thereof
EP3927728A2 (en) * 2019-02-21 2021-12-29 Xencor, Inc. Untargeted and targeted il-10 fc-fusion proteins

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