JP2023552793A5 - - Google Patents
Info
- Publication number
- JP2023552793A5 JP2023552793A5 JP2023534685A JP2023534685A JP2023552793A5 JP 2023552793 A5 JP2023552793 A5 JP 2023552793A5 JP 2023534685 A JP2023534685 A JP 2023534685A JP 2023534685 A JP2023534685 A JP 2023534685A JP 2023552793 A5 JP2023552793 A5 JP 2023552793A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- substituents
- ome
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063122690P | 2020-12-08 | 2020-12-08 | |
| US63/122,690 | 2020-12-08 | ||
| PCT/EP2021/084673 WO2022122773A1 (en) | 2020-12-08 | 2021-12-07 | 4-(2-fluoro-4-methoxy-5-3-(((1-methylcyclobutyl)methyl)carbamoyl)bicyclo[2.2.1]heptan-2-yl)carbamoyl)phenoxy)-1-methylcyclohexane-1-carboxylic acid derivatives and similar compounds as rxfp1 modulators for the treatment of heart failure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023552793A JP2023552793A (ja) | 2023-12-19 |
| JP2023552793A5 true JP2023552793A5 (cg-RX-API-DMAC10.html) | 2024-12-10 |
Family
ID=78916968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023534685A Pending JP2023552793A (ja) | 2020-12-08 | 2021-12-07 | 心不全の処置のための、ｒｘｆｐ１モデュレーターとしての４－（２－フルオロ－４－メトキシ－５－３－（（（１－メチルシクロブチル）メチル）カルバモイル）ビシクロ［２．２．１］ヘプタン－２－イル）カルバモイル）フェノキシ）－１－メチルシクロヘキサン－１－カルボン酸誘導体及び類似化合物 |
Country Status (19)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4423058A1 (en) * | 2021-10-29 | 2024-09-04 | Bristol-Myers Squibb Company | Rxfp1 agonists |
| EP4423094B1 (en) * | 2021-10-29 | 2025-12-10 | Bristol-Myers Squibb Company | Rxfp1 modulators for the treatment of heart failure |
| IL312125A (en) * | 2021-10-29 | 2024-06-01 | Bristol Myers Squibb Co | Rxfp1 agonists |
| JP2024540163A (ja) * | 2021-10-29 | 2024-10-31 | ブリストル－マイヤーズ スクイブ カンパニー | Ｒｘｆｐ１アゴニスト |
| CN119325376A (zh) * | 2022-06-07 | 2025-01-17 | 阿斯利康(瑞典)有限公司 | Rxfp1调节剂和sglt2抑制剂的组合 |
| CN119630638A (zh) * | 2022-06-07 | 2025-03-14 | 阿斯利康(瑞典)有限公司 | Rxfp1调节剂的固体形式 |
| US20260069558A1 (en) * | 2022-06-07 | 2026-03-12 | Astrazeneca Ab | Rxfp1 modulators for treating resistant hypertension or heart failure with pulmonary hypertension |
| CN121605099A (zh) * | 2023-08-10 | 2026-03-03 | 深圳信立泰药业股份有限公司 | 一种rxfp1受体调节剂及其制备方法和医药用途 |
| IL326543A (en) | 2023-08-15 | 2026-04-01 | Astrazeneca Ab | Compound azd5462 for use in the treatment of heart failure |
| TW202530177A (zh) * | 2023-10-13 | 2025-08-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 醯胺取代的環烷基類化合物、其製備方法及其在醫藥上的應用 |
| KR20260116187A (ko) | 2023-11-17 | 2026-07-28 | 일라이 릴리 앤드 캄파니 | Rxfp1 수용체 효능제 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223534A (en) * | 1989-12-04 | 1993-06-29 | G. D. Searle & Co. | Benzofuuranyl/benofuranylaklyl-N-terminal cycloalkoxy-C-terminal amino hydroxy β-amino acid derivatives |
| WO2004041795A1 (en) * | 2002-10-30 | 2004-05-21 | Guilford Pharmaceuticals Inc. | Novel inhibitors of dipeptidyl peptidase iv |
| US9452973B2 (en) * | 2012-05-04 | 2016-09-27 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Modulators of the relaxin receptor 1 |
-
2021
- 2021-12-07 AU AU2021395353A patent/AU2021395353B2/en active Active
- 2021-12-07 CN CN202180075461.3A patent/CN116547270A/zh active Pending
- 2021-12-07 WO PCT/EP2021/084673 patent/WO2022122773A1/en not_active Ceased
- 2021-12-07 TW TW110145574A patent/TW202237559A/zh unknown
- 2021-12-07 KR KR1020237022785A patent/KR20230118142A/ko active Pending
- 2021-12-07 MX MX2023006178A patent/MX2023006178A/es unknown
- 2021-12-07 PE PE2023001826A patent/PE20240655A1/es unknown
- 2021-12-07 AR ARP210103397A patent/AR124193A1/es unknown
- 2021-12-07 CR CR20230296A patent/CR20230296A/es unknown
- 2021-12-07 CA CA3203024A patent/CA3203024A1/en active Pending
- 2021-12-07 US US17/457,953 patent/US11667602B2/en active Active
- 2021-12-07 EP EP21824574.4A patent/EP4259605A1/en active Pending
- 2021-12-07 JP JP2023534685A patent/JP2023552793A/ja active Pending
- 2021-12-07 IL IL303220A patent/IL303220A/en unknown
- 2021-12-08 UY UY0001039559A patent/UY39559A/es unknown
-
2023
- 2023-02-22 US US18/172,449 patent/US20230348363A1/en active Pending
- 2023-06-01 CL CL2023001572A patent/CL2023001572A1/es unknown
- 2023-06-05 DO DO2023000111A patent/DOP2023000111A/es unknown
- 2023-06-26 CO CONC2023/0008303A patent/CO2023008303A2/es unknown
- 2023-07-04 EC ECSENADI202350133A patent/ECSP23050133A/es unknown
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