KR20230118142A - 심부전 치료용 rxfp1 조절제로서의 4-(2-플루오로-4-메톡시-5-3-(((1-메틸시클로부틸)메틸)카바모일)바이시클로[2.2.1]헵탄-2-일)카바모일)페녹시)-1-메틸시클로헥산-1-카복실산유도체 및 유사 화합물 - Google Patents

심부전 치료용 rxfp1 조절제로서의 4-(2-플루오로-4-메톡시-5-3-(((1-메틸시클로부틸)메틸)카바모일)바이시클로[2.2.1]헵탄-2-일)카바모일)페녹시)-1-메틸시클로헥산-1-카복실산유도체 및 유사 화합물 Download PDF

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KR20230118142A
KR20230118142A KR1020237022785A KR20237022785A KR20230118142A KR 20230118142 A KR20230118142 A KR 20230118142A KR 1020237022785 A KR1020237022785 A KR 1020237022785A KR 20237022785 A KR20237022785 A KR 20237022785A KR 20230118142 A KR20230118142 A KR 20230118142A
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carbamoyl
fluoro
carboxylic acid
bicyclo
methoxy
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Korean (ko)
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케네스 라르스 그란버그
줄리아 버곤지니
한스 프레드릭 버그스트룀
스티그 요나스 보스트룀
헨릭 그라덴
라르스 요한 안드레아스 울란더
시게키 사카마키
류이치 후치가미
야수키 니와
마사카주 후지오
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아스트라제네카 아베
미쓰비시 타나베 파마 코퍼레이션
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Publication of KR20230118142A publication Critical patent/KR20230118142A/ko
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KR1020237022785A 2020-12-08 2021-12-07 심부전 치료용 rxfp1 조절제로서의 4-(2-플루오로-4-메톡시-5-3-(((1-메틸시클로부틸)메틸)카바모일)바이시클로[2.2.1]헵탄-2-일)카바모일)페녹시)-1-메틸시클로헥산-1-카복실산유도체 및 유사 화합물 Pending KR20230118142A (ko)

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EP4423058A1 (en) * 2021-10-29 2024-09-04 Bristol-Myers Squibb Company Rxfp1 agonists
EP4423094B1 (en) * 2021-10-29 2025-12-10 Bristol-Myers Squibb Company Rxfp1 modulators for the treatment of heart failure
IL312125A (en) * 2021-10-29 2024-06-01 Bristol Myers Squibb Co Rxfp1 agonists
JP2024540163A (ja) * 2021-10-29 2024-10-31 ブリストル－マイヤーズ スクイブ カンパニー Ｒｘｆｐ１アゴニスト
CN119325376A (zh) * 2022-06-07 2025-01-17 阿斯利康(瑞典)有限公司 Rxfp1调节剂和sglt2抑制剂的组合
CN119630638A (zh) * 2022-06-07 2025-03-14 阿斯利康(瑞典)有限公司 Rxfp1调节剂的固体形式
US20260069558A1 (en) * 2022-06-07 2026-03-12 Astrazeneca Ab Rxfp1 modulators for treating resistant hypertension or heart failure with pulmonary hypertension
CN121605099A (zh) * 2023-08-10 2026-03-03 深圳信立泰药业股份有限公司 一种rxfp1受体调节剂及其制备方法和医药用途
IL326543A (en) 2023-08-15 2026-04-01 Astrazeneca Ab Compound azd5462 for use in the treatment of heart failure
TW202530177A (zh) * 2023-10-13 2025-08-01 大陸商江蘇恆瑞醫藥股份有限公司 醯胺取代的環烷基類化合物、其製備方法及其在醫藥上的應用
KR20260116187A (ko) 2023-11-17 2026-07-28 일라이 릴리 앤드 캄파니 Rxfp1 수용체 효능제

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