JP2023546205A5 - - Google Patents
Info
- Publication number
- JP2023546205A5 JP2023546205A5 JP2023524121A JP2023524121A JP2023546205A5 JP 2023546205 A5 JP2023546205 A5 JP 2023546205A5 JP 2023524121 A JP2023524121 A JP 2023524121A JP 2023524121 A JP2023524121 A JP 2023524121A JP 2023546205 A5 JP2023546205 A5 JP 2023546205A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- alkoxy
- hydroxy
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LULU102145 | 2020-10-21 | ||
| LU102145 | 2020-10-21 | ||
| PCT/EP2021/079141 WO2022084417A1 (en) | 2020-10-21 | 2021-10-20 | Conjugated tlr7 and nod2 agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023546205A JP2023546205A (ja) | 2023-11-01 |
| JP2023546205A5 true JP2023546205A5 (enExample) | 2024-09-06 |
Family
ID=74175904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023524121A Pending JP2023546205A (ja) | 2020-10-21 | 2021-10-20 | コンジュゲートｔｌｒ７およびｎｏｄ２アゴニスト |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230382886A1 (enExample) |
| EP (1) | EP4232094A1 (enExample) |
| JP (1) | JP2023546205A (enExample) |
| CN (1) | CN116600830A (enExample) |
| AU (1) | AU2021363606A1 (enExample) |
| CA (1) | CA3196221A1 (enExample) |
| WO (1) | WO2022084417A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024102639A1 (en) * | 2022-11-08 | 2024-05-16 | The Scripps Research Institute | N-arylpyrazole nod2 agonists as promoters of immune checkpoint inhibitor therapy |
| WO2025040743A1 (en) * | 2023-08-22 | 2025-02-27 | Univerza V Ljubljani | Conjugated tlr7 and rig-i agonists |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA200702235A1 (ru) | 2005-05-04 | 2008-04-28 | Пфайзер Лимитед | Производные 2-амидо-6-амино-8-оксопурина в качестве модуляторов toll-подобных рецепторов для лечения рака и вирусных инфекций, таких как гепатит с |
| CA2620182A1 (en) | 2005-08-22 | 2007-03-01 | Dennis A. Carson | Tlr agonists |
| JP2009542645A (ja) | 2006-07-05 | 2009-12-03 | アストラゼネカ・アクチエボラーグ | Ｔｌｒ７のモジュレーターとして作用する８−オキソアデニン誘導体 |
| EP2510946B1 (en) * | 2007-02-07 | 2015-08-05 | The Regents of The University of California | Conjugates of synthetic tlr agonists and uses therefor |
| CN102176911B (zh) | 2008-08-11 | 2014-12-10 | 葛兰素史密丝克莱恩有限责任公司 | 新的腺嘌呤衍生物 |
| KR20110117705A (ko) | 2009-02-11 | 2011-10-27 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 톨-유사 수용체 조정제 및 질병의 치료 |
| EP2563404B1 (en) | 2010-04-30 | 2016-09-21 | Urogen Pharma Ltd. | Phospholipid drug analogs |
| WO2012038058A1 (en) | 2010-09-21 | 2012-03-29 | Telormedix Sa | Treatment of conditions by toll-like receptor modulators |
| US10471139B2 (en) * | 2013-08-15 | 2019-11-12 | The University Of Kansas | Toll-like receptor agonists |
| SI3507276T1 (sl) * | 2016-09-02 | 2022-01-31 | Gilead Sciences, Inc. | Spojine modulatorja toličnih receptorjev |
| US10508115B2 (en) | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
| US10457681B2 (en) | 2017-08-16 | 2019-10-29 | Bristol_Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor |
| US10472361B2 (en) | 2017-08-16 | 2019-11-12 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor |
| WO2019197598A1 (en) | 2018-04-13 | 2019-10-17 | Glaxosmithkline Biologicals Sa | Tlr7 and / or tlr8 agonists |
| WO2019209811A1 (en) | 2018-04-24 | 2019-10-31 | Bristol-Myers Squibb Company | Macrocyclic toll-like receptor 7 (tlr7) agonists |
-
2021
- 2021-10-20 EP EP21791419.1A patent/EP4232094A1/en active Pending
- 2021-10-20 WO PCT/EP2021/079141 patent/WO2022084417A1/en not_active Ceased
- 2021-10-20 CA CA3196221A patent/CA3196221A1/en active Pending
- 2021-10-20 CN CN202180085916.XA patent/CN116600830A/zh active Pending
- 2021-10-20 AU AU2021363606A patent/AU2021363606A1/en active Pending
- 2021-10-20 US US18/032,612 patent/US20230382886A1/en active Pending
- 2021-10-20 JP JP2023524121A patent/JP2023546205A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5779592B2 (ja) | ラコサミドの合成のための方法 | |
| JP2020169171A5 (enExample) | ||
| EP3077404B1 (en) | Purification of tenofovir alafenamide and its intermediates | |
| JP2024504932A5 (enExample) | ||
| JP2022551185A5 (enExample) | ||
| JP2024522174A5 (enExample) | ||
| JP2010530881A5 (enExample) | ||
| JP2009507011A5 (enExample) | ||
| JP2021523200A5 (enExample) | ||
| CN109563133A (zh) | 多酰胺化合物及其用途 | |
| RU2006125630A (ru) | Дифенилаэетидиноновые производные, обладающие активностью, ингибирующей всасывание холестерина | |
| JP2010511626A5 (enExample) | ||
| JP2024545787A5 (enExample) | ||
| RU2007147344A (ru) | Новые производные 2-азетидинона для лечения гиперлипидемических заболеваний | |
| JP2005536503A5 (enExample) | ||
| JP2022529321A5 (enExample) | ||
| JP2014505017A5 (enExample) | ||
| RU2007147340A (ru) | Новые производные 2-азетидинона в качестве ингибиторов всасывания холестерина для лечения гиперлипидемических состояний | |
| JP2017518363A5 (enExample) | ||
| JP2004529172A5 (enExample) | ||
| JP2023503898A5 (enExample) | ||
| JP2009536188A5 (enExample) | ||
| IL274283B1 (en) | Method for the synthesis of cyclic depsipeptides | |
| RU2009132657A (ru) | Новые индольные производные, способ их получения и их применение в качестве антибактериальных средств | |
| JP2023511152A5 (enExample) |