JP2023544387A5 - - Google Patents
Info
- Publication number
- JP2023544387A5 JP2023544387A5 JP2023520305A JP2023520305A JP2023544387A5 JP 2023544387 A5 JP2023544387 A5 JP 2023544387A5 JP 2023520305 A JP2023520305 A JP 2023520305A JP 2023520305 A JP2023520305 A JP 2023520305A JP 2023544387 A5 JP2023544387 A5 JP 2023544387A5
- Authority
- JP
- Japan
- Prior art keywords
- gdf3
- level
- patient
- risk
- cardiac remodeling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20306156 | 2020-10-05 | ||
| EP20306156.9 | 2020-10-05 | ||
| PCT/EP2021/077267 WO2022073915A1 (en) | 2020-10-05 | 2021-10-04 | Gdf3 as biomarker and biotarget in post-ischemic cardiac remodeling |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023544387A JP2023544387A (ja) | 2023-10-23 |
| JP2023544387A5 true JP2023544387A5 (https=) | 2024-08-14 |
| JP7823034B2 JP7823034B2 (ja) | 2026-03-03 |
Family
ID=72944085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023520305A Active JP7823034B2 (ja) | 2020-10-05 | 2021-10-04 | 虚血後の心臓リモデリングにおけるバイオマーカー及びバイオターゲットとしてのgdf3 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20230375571A1 (https=) |
| EP (1) | EP4226160A1 (https=) |
| JP (1) | JP7823034B2 (https=) |
| WO (1) | WO2022073915A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114859061B (zh) * | 2022-05-06 | 2024-10-18 | 华中科技大学同济医学院附属协和医院 | 预测心梗患者有害心室重塑和免疫治疗疗效的标志物及其应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5808007A (en) * | 1993-01-12 | 1998-09-15 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-3 |
| EP0690452A3 (en) | 1994-06-28 | 1999-01-07 | Advanced Micro Devices, Inc. | Electrically erasable memory and method of erasure |
| US6566131B1 (en) | 2000-10-04 | 2003-05-20 | Isis Pharmaceuticals, Inc. | Antisense modulation of Smad6 expression |
| US6410323B1 (en) | 1999-08-31 | 2002-06-25 | Isis Pharmaceuticals, Inc. | Antisense modulation of human Rho family gene expression |
| US6107091A (en) | 1998-12-03 | 2000-08-22 | Isis Pharmaceuticals Inc. | Antisense inhibition of G-alpha-16 expression |
| US5981732A (en) | 1998-12-04 | 1999-11-09 | Isis Pharmaceuticals Inc. | Antisense modulation of G-alpha-13 expression |
| US6046321A (en) | 1999-04-09 | 2000-04-04 | Isis Pharmaceuticals Inc. | Antisense modulation of G-alpha-i1 expression |
| US6365354B1 (en) | 2000-07-31 | 2002-04-02 | Isis Pharmaceuticals, Inc. | Antisense modulation of lysophospholipase I expression |
| US6566135B1 (en) | 2000-10-04 | 2003-05-20 | Isis Pharmaceuticals, Inc. | Antisense modulation of caspase 6 expression |
| EP1771557B1 (en) * | 2004-06-24 | 2014-12-31 | Acceleron Pharma Inc. | GDF3 Propeptides and Related Methods |
| US7611834B2 (en) | 2005-09-30 | 2009-11-03 | Sandia Corporation | Methods and devices for protein assays |
| US20090082552A1 (en) | 2007-09-26 | 2009-03-26 | Magdalena Bynum | Microfluidic protein assay |
| EP2632950B1 (en) * | 2010-10-26 | 2018-08-22 | UMC Utrecht Holding B.V. | Antibody binding to fibronectin-eda for preventing myocardial infarction-related complications |
| WO2013137715A1 (en) * | 2012-03-16 | 2013-09-19 | Umc Utrecht Holding B.V. | Biomarkers for adverse cardiac remodeling |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| WO2017189605A1 (en) * | 2016-04-25 | 2017-11-02 | Siemens Healthcare Diagnostics Inc. | Diagnostic method(s) for detecting and treating post-infarct myocardium remodeling and diffuse myocardial fibrosis |
| CA3052625A1 (en) * | 2017-02-06 | 2018-08-09 | Acceleron Pharma Inc. | Compositions and methods for treating heart failure |
| EP3409778A1 (en) * | 2017-05-31 | 2018-12-05 | Medizinische Hochschule Hannover | Lncrnas gadlor 1 and 2 for use in treating and preventing cardiac remodelling |
| JP2022512648A (ja) * | 2018-10-09 | 2022-02-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 心筋線維化の処置のためのαV-インテグリン(CD51)阻害剤の使用 |
-
2021
- 2021-10-04 WO PCT/EP2021/077267 patent/WO2022073915A1/en not_active Ceased
- 2021-10-04 EP EP21805839.4A patent/EP4226160A1/en active Pending
- 2021-10-04 JP JP2023520305A patent/JP7823034B2/ja active Active
- 2021-10-04 US US18/247,945 patent/US20230375571A1/en active Pending
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