JP2023542212A5 - - Google Patents

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Publication number
JP2023542212A5
JP2023542212A5 JP2023518392A JP2023518392A JP2023542212A5 JP 2023542212 A5 JP2023542212 A5 JP 2023542212A5 JP 2023518392 A JP2023518392 A JP 2023518392A JP 2023518392 A JP2023518392 A JP 2023518392A JP 2023542212 A5 JP2023542212 A5 JP 2023542212A5
Authority
JP
Japan
Prior art keywords
seq
cell
bispecific antibody
variable region
chain variable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023518392A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023542212A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/075995 external-priority patent/WO2022063803A1/en
Publication of JP2023542212A publication Critical patent/JP2023542212A/ja
Publication of JP2023542212A5 publication Critical patent/JP2023542212A5/ja
Pending legal-status Critical Current

Links

JP2023518392A 2020-09-24 2021-09-22 T細胞二重特異性抗体に関連する有害作用の予防又は緩和 Pending JP2023542212A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP20198050 2020-09-24
EP20198050.5 2020-09-24
EP20201583.0 2020-10-13
EP20201583 2020-10-13
EP21172627 2021-05-07
EP21172627.8 2021-05-07
PCT/EP2021/075995 WO2022063803A1 (en) 2020-09-24 2021-09-22 Prevention or mitigation of t-cell bispecific antibody-related adverse effects

Publications (2)

Publication Number Publication Date
JP2023542212A JP2023542212A (ja) 2023-10-05
JP2023542212A5 true JP2023542212A5 (https=) 2024-09-30

Family

ID=78000677

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023518392A Pending JP2023542212A (ja) 2020-09-24 2021-09-22 T細胞二重特異性抗体に関連する有害作用の予防又は緩和

Country Status (12)

Country Link
US (1) US20220088195A1 (https=)
EP (1) EP4216998A1 (https=)
JP (1) JP2023542212A (https=)
KR (1) KR20230074146A (https=)
CN (1) CN116322691A (https=)
AU (1) AU2021350075A1 (https=)
BR (1) BR112023005399A2 (https=)
CA (1) CA3193478A1 (https=)
IL (1) IL300543A (https=)
MX (1) MX2023003133A (https=)
TW (1) TW202228773A (https=)
WO (1) WO2022063803A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
EP4619428A1 (en) * 2022-11-15 2025-09-24 F. Hoffmann-La Roche AG Antigen binding molecules

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
GB9114948D0 (en) 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
FI941572A7 (fi) 1991-10-07 1994-05-27 Oncologix Inc Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
CA2372813A1 (en) 1992-02-06 1993-08-19 L.L. Houston Biosynthetic binding protein for cancer marker
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
LT2961771T (lt) 2013-02-26 2020-03-10 Roche Glycart Ag Bispecifinės t ląstelę aktyvinančios antigeną surišančios molekulės, specifinės cd3 ir cea antigenams
EP3066130B1 (en) * 2013-11-07 2019-05-15 Memorial Sloan-Kettering Cancer Center Anti-wt1/hla bi-specific antibody
EP3177643B1 (en) 2014-08-04 2019-05-08 F.Hoffmann-La Roche Ag Bispecific t cell activating antigen binding molecules
KR20230148844A (ko) * 2016-03-29 2023-10-25 유니버시티 오브 써던 캘리포니아 암을 표적하는 키메라 항원 수용체
US20200101108A1 (en) * 2017-03-31 2020-04-02 The Board Of Trustees Of The Le-Land Standford Junior University Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
CN111699001A (zh) * 2017-12-07 2020-09-22 尤利乌斯·马克西米利安维尔茨堡大学 达沙替尼和其他酪氨酸激酶抑制剂对基因修饰的嵌合抗原受体t细胞的功能的控制和调节
MX2020006119A (es) * 2017-12-21 2020-08-24 Hoffmann La Roche Anticuerpos de union a hla-a2/wt1.
WO2020077258A1 (en) * 2018-10-12 2020-04-16 Jeanmarie Guenot Cd33×cd3 binding proteins for treating inflammatory conditions and diseases

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