JP2023547523A5 - - Google Patents

Info

Publication number
JP2023547523A5
JP2023547523A5 JP2023526938A JP2023526938A JP2023547523A5 JP 2023547523 A5 JP2023547523 A5 JP 2023547523A5 JP 2023526938 A JP2023526938 A JP 2023526938A JP 2023526938 A JP2023526938 A JP 2023526938A JP 2023547523 A5 JP2023547523 A5 JP 2023547523A5
Authority
JP
Japan
Prior art keywords
seq
variable region
chain variable
hcdr
lcdr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023526938A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023547523A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/080888 external-priority patent/WO2022101120A1/en
Publication of JP2023547523A publication Critical patent/JP2023547523A/ja
Publication of JP2023547523A5 publication Critical patent/JP2023547523A5/ja
Pending legal-status Critical Current

Links

JP2023526938A 2020-11-10 2021-11-08 T細胞係合剤関連の有害作用の防止又は軽減 Pending JP2023547523A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP20206567 2020-11-10
EP20206567.8 2020-11-10
EP21155823.4 2021-02-08
EP21155823 2021-02-08
EP21172623 2021-05-07
EP21172623.7 2021-05-07
EP21187472.2 2021-07-23
EP21187472 2021-07-23
PCT/EP2021/080888 WO2022101120A1 (en) 2020-11-10 2021-11-08 Prevention or mitigation of t-cell engaging agent-related adverse effects

Publications (2)

Publication Number Publication Date
JP2023547523A JP2023547523A (ja) 2023-11-10
JP2023547523A5 true JP2023547523A5 (https=) 2024-11-14

Family

ID=78528969

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023526938A Pending JP2023547523A (ja) 2020-11-10 2021-11-08 T細胞係合剤関連の有害作用の防止又は軽減

Country Status (10)

Country Link
US (1) US20220168418A1 (https=)
EP (1) EP4243856A1 (https=)
JP (1) JP2023547523A (https=)
KR (1) KR20230107235A (https=)
AU (1) AU2021380807A1 (https=)
CA (1) CA3196810A1 (https=)
IL (1) IL302570A (https=)
MX (1) MX2023005306A (https=)
TW (1) TW202233231A (https=)
WO (1) WO2022101120A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
GB9114948D0 (en) 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
FI941572A7 (fi) 1991-10-07 1994-05-27 Oncologix Inc Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
CA2372813A1 (en) 1992-02-06 1993-08-19 L.L. Houston Biosynthetic binding protein for cancer marker
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
LT2961771T (lt) 2013-02-26 2020-03-10 Roche Glycart Ag Bispecifinės t ląstelę aktyvinančios antigeną surišančios molekulės, specifinės cd3 ir cea antigenams
EP3177643B1 (en) 2014-08-04 2019-05-08 F.Hoffmann-La Roche Ag Bispecific t cell activating antigen binding molecules
EP3233918A1 (en) * 2014-12-19 2017-10-25 Novartis AG Combination therapies
NL2014935B1 (en) * 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
KR20230148844A (ko) * 2016-03-29 2023-10-25 유니버시티 오브 써던 캘리포니아 암을 표적하는 키메라 항원 수용체
WO2018220099A1 (en) * 2017-06-02 2018-12-06 F. Hoffmann-La Roche Ag Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
SG11201900344YA (en) * 2016-07-15 2019-02-27 Novartis Ag Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
WO2020169698A1 (en) * 2019-02-21 2020-08-27 F. Hoffmann-La Roche Ag Sensitization of cancer cells to tnf by bet inhibition

Similar Documents

Publication Publication Date Title
JP2023547523A5 (https=)
KR101092132B1 (ko) 키메라 항-cd20항체를 이용한 순환성 종양세포와 관련된 혈액학적 악성종양의 치료법
JP2024156736A5 (https=)
Remberger et al. Effect on cytokine release and graft-versus-host disease of different anti-T cell antibodies during conditioning for unrelated haematopoietic stem cell transplantation
JP2024514281A5 (https=)
JP2021509009A5 (https=)
JP2018512170A5 (https=)
CN103933573A (zh) 用于治疗免疫病症的联合治疗
JP2023542212A5 (https=)
CN111683677A (zh) 使用抗体-药物缀合物调节免疫应答
CN112351795A (zh) 采用抗癌药剂和以包含非典型hla-i及新抗原复合物为靶点的抗体的联合抗癌疗法
Di Filippo Anti‐IL‐2 receptor antibody vs. polyclonal anti‐lymphocyte antibody as induction therapy in pediatric transplantation
KR20240046170A (ko) B-세포 악성종양의 치료에 사용하기 위한 조성물
JP7492752B2 (ja) 免疫療法のためのアジュバントとしてのグアナベンズ
CN102245205A (zh) 用于减少b-辅助性t细胞以治疗自身免疫疾病的方法
JP2023546657A5 (https=)
Schattner et al. Natural killer cells—toward clinical application
KR20230005142A (ko) 인터루킨 억제제와 조합된 clever-1 억제제를 통한 질환의 치료
CN1527840A (zh) Cd25结合分子在类固醇耐受型患者中的用途
WO2018085775A1 (en) Methods and compositions for treating multiple myeloma and increasing antibody dependent cell cytotoxicity by targeting the aryl hydrocarbon receptor
RU2318537C2 (ru) Применение cd25-связывающих молекул для лечения пациентов, устойчивых к стероидам
Durlik Treatment of antibody-mediated rejection in kidney transplantation
WO2025021587A1 (en) Combination of a mps1 inhibitor and immune checkpoint inhibitors, uses and pharmaceutical compositions thereof
CN121693348A (zh) 肿瘤联合治疗及使用方法
HK1161088A (en) Methods to reduce b-helper t cells to treat autoimmune diseases