JP2023540558A5 - - Google Patents
Info
- Publication number
- JP2023540558A5 JP2023540558A5 JP2023515088A JP2023515088A JP2023540558A5 JP 2023540558 A5 JP2023540558 A5 JP 2023540558A5 JP 2023515088 A JP2023515088 A JP 2023515088A JP 2023515088 A JP2023515088 A JP 2023515088A JP 2023540558 A5 JP2023540558 A5 JP 2023540558A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- independently selected
- ring
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020113758 | 2020-09-07 | ||
| CNPCT/CN2020/113758 | 2020-09-07 | ||
| PCT/CN2021/116684 WO2022048665A1 (en) | 2020-09-07 | 2021-09-06 | Heterocyclic glp-1 agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023540558A JP2023540558A (ja) | 2023-09-25 |
| JP2023540558A5 true JP2023540558A5 (https=) | 2024-09-12 |
| JP7821785B2 JP7821785B2 (ja) | 2026-02-27 |
Family
ID=80491636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023515088A Active JP7821785B2 (ja) | 2020-09-07 | 2021-09-06 | ヘテロ環ｇｌｐ－１アゴニスト |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230322771A1 (https=) |
| EP (1) | EP4211133A4 (https=) |
| JP (1) | JP7821785B2 (https=) |
| CN (1) | CN116615430A (https=) |
| WO (1) | WO2022048665A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202206429A (zh) | 2020-04-29 | 2022-02-16 | 美商迦舒布魯姆生物有限公司 | 雜環ｇｌｐ—１促效劑 |
| JP2023537501A (ja) | 2020-08-06 | 2023-09-01 | ガシャーブラム・バイオ・インコーポレイテッド | ヘテロ環ｇｌｐ－１アゴニスト |
| CN116368140A (zh) | 2020-09-10 | 2023-06-30 | 加舒布鲁姆生物公司 | 杂环glp-1激动剂 |
| WO2023029380A1 (zh) | 2021-08-30 | 2023-03-09 | 杭州德睿智药科技有限公司 | 作为glp1r激动剂的新型芳醚取代杂环类化合物 |
| PT4408840T (pt) | 2021-09-27 | 2025-10-07 | Terns Pharmaceuticals Inc | Ácidos benzimidazolocarboxílicos como agonistas de glp-1r |
| CN118401519A (zh) | 2021-10-25 | 2024-07-26 | 拓臻制药公司 | 作为glp-1r激动剂的化合物 |
| CN119095843A (zh) | 2022-02-23 | 2024-12-06 | 拓臻制药公司 | 作为glp-1r激动剂的化合物 |
| US20250206757A1 (en) * | 2022-03-21 | 2025-06-26 | Gasherbrum Bio, Inc. | 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes |
| EP4522131A1 (en) * | 2022-05-11 | 2025-03-19 | Eli Lilly and Company | Glp1 tablet compositions |
| EP4652167A1 (en) * | 2023-01-17 | 2025-11-26 | Fochon Biosciences, Ltd. | Glp-1r agonists and uses thereof |
| CN120957993A (zh) | 2023-02-16 | 2025-11-14 | 加舒布鲁姆生物公司 | 杂环glp-1激动剂 |
| EP4568664B1 (en) | 2023-04-07 | 2026-04-01 | Terns Pharmaceuticals, Inc. | Combination comprising a thr-beta agonist and a glp-1r agonist for use in treating obesity |
| WO2025002250A1 (zh) * | 2023-06-29 | 2025-01-02 | 韦恩生物科技有限公司 | 一种glp-1受体激动剂及其制备方法和用途 |
| IL325536A (en) * | 2023-06-30 | 2026-02-01 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | A compound containing a multi-fused ring structure |
| TW202508571A (zh) * | 2023-07-28 | 2025-03-01 | 大陸商上海翰森生物醫藥科技有限公司 | 一種苯并含氮雜環類衍生物調節劑、其製備方法和應用 |
| WO2025026436A1 (zh) * | 2023-08-02 | 2025-02-06 | 韦恩生物科技有限公司 | 一种含氮并环化合物及其制备方法和用途 |
| WO2025045208A1 (en) * | 2023-08-31 | 2025-03-06 | Gasherbrum Bio, Inc. | Heteroaryl-heterocycloalkyl-based glp-1 agonists |
| CN120981457A (zh) * | 2023-09-14 | 2025-11-18 | 歌礼制药(中国)有限公司 | Glp-1r激动剂及其治疗方法 |
| CN121941685A (zh) | 2023-11-10 | 2026-04-28 | 重庆药友制药有限责任公司 | 一种glp-1r激动剂化合物及其应用 |
| TW202521534A (zh) | 2023-11-24 | 2025-06-01 | 香港商歌禮製藥(中國)有限公司 | Glp-1r 激動劑及其治療方法 |
| TW202542146A (zh) * | 2023-12-05 | 2025-11-01 | 大陸商信達生物科技有限公司 | 靶向ｇｌｐ－１受體的化合物以及其用途 |
| WO2025158275A1 (en) | 2024-01-24 | 2025-07-31 | Pfizer Inc. | Combination therapy using glucose-dependent insulinotropic polypeptide receptor antagonist compounds and glp-1 receptor agonist compounds |
| TW202600132A (zh) | 2024-03-08 | 2026-01-01 | 美商安尼波那生物公司 | 用於治療肥胖症及提高減重之方法 |
| WO2025209515A1 (zh) * | 2024-04-03 | 2025-10-09 | 广州市联瑞制药有限公司 | 一种glp-1受体激动剂及其制备方法和应用 |
| WO2025264023A1 (en) * | 2024-06-19 | 2025-12-26 | Chong Kun Dang Pharmaceutical Corp. | Glp-1 receptor agonist, and uses thereof |
| WO2026031819A1 (en) * | 2024-08-06 | 2026-02-12 | Insilico Medicine Ip Limited | Novel compounds as glp-1r agonists and uses thereof |
| CN119176808B (zh) * | 2024-11-25 | 2025-12-26 | 山东法恩新材料科技有限公司 | 一种glp-1激动剂及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6927214B1 (en) * | 1999-01-15 | 2005-08-09 | Novo Nordisk A/S | Non-peptide GLP-1 agonists |
| JOP20190060A1 (ar) * | 2016-09-26 | 2019-03-26 | Chugai Pharmaceutical Co Ltd | مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1 |
| JP7461104B2 (ja) * | 2017-11-29 | 2024-04-03 | 中外製薬株式会社 | Ｇｌｐ－１受容体アゴニスト作用を持つピラゾロピリジン誘導体を含有する医薬組成物 |
-
2021
- 2021-09-06 EP EP21863727.0A patent/EP4211133A4/en active Pending
- 2021-09-06 US US18/044,196 patent/US20230322771A1/en active Pending
- 2021-09-06 WO PCT/CN2021/116684 patent/WO2022048665A1/en not_active Ceased
- 2021-09-06 CN CN202180073815.0A patent/CN116615430A/zh active Pending
- 2021-09-06 JP JP2023515088A patent/JP7821785B2/ja active Active
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