JP2023540490A5 - - Google Patents

Info

Publication number
JP2023540490A5
JP2023540490A5 JP2023514117A JP2023514117A JP2023540490A5 JP 2023540490 A5 JP2023540490 A5 JP 2023540490A5 JP 2023514117 A JP2023514117 A JP 2023514117A JP 2023514117 A JP2023514117 A JP 2023514117A JP 2023540490 A5 JP2023540490 A5 JP 2023540490A5
Authority
JP
Japan
Prior art keywords
antagonist
heavy chain
light chain
olimbacimab
pembrolizumab
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023514117A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023540490A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/058043 external-priority patent/WO2022049526A1/en
Publication of JP2023540490A publication Critical patent/JP2023540490A/ja
Publication of JP2023540490A5 publication Critical patent/JP2023540490A5/ja
Pending legal-status Critical Current

Links

JP2023514117A 2020-09-02 2021-09-02 がん患者を治療するためのpd-1拮抗薬及びvegfr-2拮抗薬の併用療法 Pending JP2023540490A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063073512P 2020-09-02 2020-09-02
US63/073,512 2020-09-02
US202063122321P 2020-12-07 2020-12-07
US63/122,321 2020-12-07
PCT/IB2021/058043 WO2022049526A1 (en) 2020-09-02 2021-09-02 Combination therapy of a pd-1 antagonist and an antagonist for vegfr-2 for treating patients with cancer

Publications (2)

Publication Number Publication Date
JP2023540490A JP2023540490A (ja) 2023-09-25
JP2023540490A5 true JP2023540490A5 (enExample) 2024-08-21

Family

ID=77914405

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023514117A Pending JP2023540490A (ja) 2020-09-02 2021-09-02 がん患者を治療するためのpd-1拮抗薬及びvegfr-2拮抗薬の併用療法

Country Status (8)

Country Link
US (1) US20230265196A1 (enExample)
EP (1) EP4208482A1 (enExample)
JP (1) JP2023540490A (enExample)
KR (1) KR20230087451A (enExample)
AU (1) AU2021337223A1 (enExample)
CA (1) CA3189987A1 (enExample)
MX (1) MX2023002570A (enExample)
WO (1) WO2022049526A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20260116273A (ko) 2024-09-20 2026-07-28 파라곤 테라퓨틱스, 인크. Pd-1 결합 단백질, vegf 및 pd-1 이중특이적 결합 단백질, 조성물 및 사용 방법

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
WO2000032634A1 (en) 1998-12-01 2000-06-08 Protein Design Labs, Inc. Humanized antibodies to gamma-interferon
PT1916001E (pt) 2002-03-04 2011-07-18 Imclone Llc Anticorpos humanos específicos para kdr e suas utilizações
DE60334303D1 (de) 2002-07-03 2010-11-04 Tasuku Honjo Immunpotenzierende zusammensetzungen
ES2367430T3 (es) 2002-12-23 2011-11-03 Wyeth Llc Anticuerpos contra pd-1 y sus usos.
US7563869B2 (en) 2003-01-23 2009-07-21 Ono Pharmaceutical Co., Ltd. Substance specific to human PD-1
EP3530736A3 (en) 2005-05-09 2019-11-06 ONO Pharmaceutical Co., Ltd. Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
KR101704734B1 (ko) 2005-07-01 2017-02-09 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
PT2170959E (pt) 2007-06-18 2014-01-07 Merck Sharp & Dohme Anticorpos para o receptor humano de morte programada pd-1
US8168757B2 (en) 2008-03-12 2012-05-01 Merck Sharp & Dohme Corp. PD-1 binding proteins
WO2010098788A2 (en) 2008-08-25 2010-09-02 Amplimmune, Inc. Pd-i antagonists and methods for treating infectious disease
EA201500417A1 (ru) 2008-08-25 2015-11-30 Эмплиммьюн, Инк. Композиции антагонистов pd-1 и способы применения
WO2010036959A2 (en) 2008-09-26 2010-04-01 Dana-Farber Cancer Institute Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
EP2504028A4 (en) 2009-11-24 2014-04-09 Amplimmune Inc SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2
WO2012135408A1 (en) 2011-03-31 2012-10-04 Merck Sharp & Dohme Corp. Stable formulations of antibodies to human programmed death receptor pd-1 and related treatments
BR112014002353B1 (pt) 2011-08-01 2022-09-27 Genentech, Inc Usos de antagonistas de ligação do eixo pd-1 e inibidores de mek, composições farmacêuticas, e kit
RS61400B1 (sr) 2013-05-02 2021-02-26 Anaptysbio Inc Antitela usmerena protiv programirane smrti-1 (pd-1)
CA3175360C (en) 2013-05-31 2024-05-28 Sorrento Therapeutics, Inc. Antigen binding proteins that bind pd-1
SMT202300039T1 (it) 2013-09-13 2023-03-17 Beigene Switzerland Gmbh Anticorpi anti-pd1 e loro uso come terapia e per diagnostica
CR20160319A (es) 2013-12-12 2016-11-08 Jiangsu Hengrui Medicine Co Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este
TWI681969B (zh) 2014-01-23 2020-01-11 美商再生元醫藥公司 針對pd-1的人類抗體
UA122479C2 (uk) 2014-01-24 2020-11-25 Дана-Фарбер Кенсер Інстітьют, Інк. Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
EP3463456A1 (en) * 2016-06-03 2019-04-10 ImClone LLC Combination of ramucirumab and pembrolizumab for the treatment of certain cancers

Similar Documents

Publication Publication Date Title
JP2022512851A5 (enExample)
JP2025016606A5 (enExample)
JP2017501167A5 (enExample)
HRP20231156T1 (hr) Kombinacija anti-pd-1 antitijela i bispecifičnih anti-cd20/anti-cd3 antitijela za liječenje raka
JP2017501157A5 (enExample)
JP2021501162A5 (enExample)
JP2017514795A5 (enExample)
JP2020503260A5 (enExample)
JP2019515008A5 (enExample)
JP2021513540A5 (enExample)
JP2017533912A5 (enExample)
JP2017514461A5 (enExample)
JP2017507652A5 (enExample)
JP2019502676A5 (enExample)
JP2014533279A5 (enExample)
JP2015534579A5 (enExample)
JP2013520442A5 (enExample)
JP2018508483A5 (enExample)
JP2017507900A5 (enExample)
JP2018505177A5 (enExample)
JP2023524149A5 (enExample)
RU2018111529A (ru) Комбинированная терапия для лечения рака
JP2018536632A5 (ja) B7‐h3に特異的に結合する分子及びpd‐1に特異的に結合する分子
JP2024541680A5 (enExample)
JP2015517529A5 (enExample)