JP2023539154A - エトポシドトニリベート製剤 - Google Patents

エトポシドトニリベート製剤 Download PDF

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Publication number
JP2023539154A
JP2023539154A JP2023512354A JP2023512354A JP2023539154A JP 2023539154 A JP2023539154 A JP 2023539154A JP 2023512354 A JP2023512354 A JP 2023512354A JP 2023512354 A JP2023512354 A JP 2023512354A JP 2023539154 A JP2023539154 A JP 2023539154A
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JP
Japan
Prior art keywords
pharmaceutical formulation
liquid pharmaceutical
infusion
etoposide
tonilibate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023512354A
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English (en)
Japanese (ja)
Other versions
JP2023539154A5 (https=
Inventor
グッヂ，ダビデ
バスケス，アンナ モンテス
ルビオ，ハビエル マルティネス
トーマ，ルディ
Original Assignee
セラクト ファーマ ジーエムビーエイチ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2012956.5A external-priority patent/GB202012956D0/en
Priority claimed from GBGB2012954.0A external-priority patent/GB202012954D0/en
Application filed by セラクト ファーマ ジーエムビーエイチ filed Critical セラクト ファーマ ジーエムビーエイチ
Publication of JP2023539154A publication Critical patent/JP2023539154A/ja
Publication of JP2023539154A5 publication Critical patent/JP2023539154A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023512354A 2020-08-19 2021-08-19 エトポシドトニリベート製剤 Pending JP2023539154A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2012954.0 2020-08-19
GBGB2012956.5A GB202012956D0 (en) 2020-08-19 2020-08-19 Etoposide toniribate formulation
GB2012956.5 2020-08-19
GBGB2012954.0A GB202012954D0 (en) 2020-08-19 2020-08-19 Etoposide toniribate formulation
PCT/EP2021/073034 WO2022038226A1 (en) 2020-08-19 2021-08-19 Etoposide toniribate formulation

Publications (2)

Publication Number Publication Date
JP2023539154A true JP2023539154A (ja) 2023-09-13
JP2023539154A5 JP2023539154A5 (https=) 2024-08-27

Family

ID=80322580

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023512354A Pending JP2023539154A (ja) 2020-08-19 2021-08-19 エトポシドトニリベート製剤

Country Status (7)

Country Link
US (1) US20230398069A1 (https=)
EP (1) EP4199933A1 (https=)
JP (1) JP2023539154A (https=)
KR (1) KR20230131815A (https=)
AU (1) AU2021327164A1 (https=)
CA (1) CA3189720A1 (https=)
WO (1) WO2022038226A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4233837A1 (en) * 2022-02-24 2023-08-30 CellAct Pharma GmbH Solid and oral etoposide toniribate compositions
CN116983259A (zh) * 2023-09-27 2023-11-03 成都瑞尔医药科技有限公司 一种依托泊苷注射液的制备方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09507233A (ja) * 1993-12-29 1997-07-22 マトリクス ファーマスーティカル，インコーポレイティド 細胞増殖性疾患に罹る宿主の治療方法及び治療のための組成物
JP2003509385A (ja) * 1999-09-13 2003-03-11 ノベックス・コーポレイション 両親媒性プロドラッグ
JP2004346023A (ja) * 2003-05-23 2004-12-09 Nippon Kayaku Co Ltd 前立腺癌の局所治療剤
JP2008543789A (ja) * 2005-06-17 2008-12-04 ホスピラ オーストラリア ピーティーワイ エルティーディー ドセタキセルの液体薬学的処方物
JP2010120943A (ja) * 2001-12-03 2010-06-03 Universitaetsklinikum Charite Der Humboldt-Univ Zu Berlin Technologie Transferstelle ポドフィロトキシン
WO2011128115A1 (en) * 2010-04-16 2011-10-20 Cellact Pharma Gmbh Analogues of etoposide for the treatment of tumours
JP2014512402A (ja) * 2011-04-28 2014-05-22 オンコペプティデス エービー 細胞毒性ジペプチドの凍結乾燥調製物
WO2014140072A1 (en) * 2013-03-12 2014-09-18 Cellact Pharma Gmbh Etoposide and prodrugs thereof for use in targeting cancer stem cells

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102122429B1 (ko) * 2011-04-28 2020-06-12 온코펩타이드즈 아베 세포독성 디펩티드의 동결건조 제제

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09507233A (ja) * 1993-12-29 1997-07-22 マトリクス ファーマスーティカル，インコーポレイティド 細胞増殖性疾患に罹る宿主の治療方法及び治療のための組成物
JP2003509385A (ja) * 1999-09-13 2003-03-11 ノベックス・コーポレイション 両親媒性プロドラッグ
JP2010120943A (ja) * 2001-12-03 2010-06-03 Universitaetsklinikum Charite Der Humboldt-Univ Zu Berlin Technologie Transferstelle ポドフィロトキシン
JP2004346023A (ja) * 2003-05-23 2004-12-09 Nippon Kayaku Co Ltd 前立腺癌の局所治療剤
JP2008543789A (ja) * 2005-06-17 2008-12-04 ホスピラ オーストラリア ピーティーワイ エルティーディー ドセタキセルの液体薬学的処方物
WO2011128115A1 (en) * 2010-04-16 2011-10-20 Cellact Pharma Gmbh Analogues of etoposide for the treatment of tumours
JP2013525287A (ja) * 2010-04-16 2013-06-20 ツェルアクト ファーマ ゲーエムベーハー 腫瘍の処置のためのエポトシドのアナログ
JP2014512402A (ja) * 2011-04-28 2014-05-22 オンコペプティデス エービー 細胞毒性ジペプチドの凍結乾燥調製物
WO2014140072A1 (en) * 2013-03-12 2014-09-18 Cellact Pharma Gmbh Etoposide and prodrugs thereof for use in targeting cancer stem cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"ベプシド注１００ｍｇ", 添付文書, vol. 第18版, JPN6025036508, ISSN: 0005819942 *

Also Published As

Publication number Publication date
KR20230131815A (ko) 2023-09-14
US20230398069A1 (en) 2023-12-14
WO2022038226A1 (en) 2022-02-24
EP4199933A1 (en) 2023-06-28
AU2021327164A1 (en) 2023-03-16
CA3189720A1 (en) 2022-02-24

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