JP2023538807A5 - - Google Patents

Info

Publication number
JP2023538807A5
JP2023538807A5 JP2023502703A JP2023502703A JP2023538807A5 JP 2023538807 A5 JP2023538807 A5 JP 2023538807A5 JP 2023502703 A JP2023502703 A JP 2023502703A JP 2023502703 A JP2023502703 A JP 2023502703A JP 2023538807 A5 JP2023538807 A5 JP 2023538807A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
sar
compstatin analog
acceptable salt
peg3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023502703A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023538807A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/069798 external-priority patent/WO2022013374A1/en
Publication of JP2023538807A publication Critical patent/JP2023538807A/ja
Publication of JP2023538807A5 publication Critical patent/JP2023538807A5/ja
Pending legal-status Critical Current

Links

JP2023502703A 2020-07-16 2021-07-15 補体因子c3の阻害剤及びそれらの医学的使用 Pending JP2023538807A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20186297 2020-07-16
EP20186297.6 2020-07-16
PCT/EP2021/069798 WO2022013374A1 (en) 2020-07-16 2021-07-15 Inhibitors of complement factor c3 and their medical uses

Publications (2)

Publication Number Publication Date
JP2023538807A JP2023538807A (ja) 2023-09-12
JP2023538807A5 true JP2023538807A5 (https=) 2024-07-24

Family

ID=71661768

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023502703A Pending JP2023538807A (ja) 2020-07-16 2021-07-15 補体因子c3の阻害剤及びそれらの医学的使用

Country Status (11)

Country Link
US (1) US20230287051A1 (https=)
EP (1) EP4182023A1 (https=)
JP (1) JP2023538807A (https=)
KR (1) KR20230039718A (https=)
CN (1) CN116209671A (https=)
AU (1) AU2021309548A1 (https=)
CA (1) CA3185730A1 (https=)
CO (1) CO2023001411A2 (https=)
IL (1) IL299870A (https=)
MX (1) MX2023000679A (https=)
WO (1) WO2022013374A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2020128624A (ru) 2018-02-27 2022-03-28 Зп Спв 3 К/С Аналоги компстатина и их медицинское применение
CA3204051A1 (en) 2021-01-20 2022-07-28 Brian Lian Compositions and methods for the treatment of metabolic and liver disorders
JP7642830B2 (ja) 2021-09-15 2025-03-10 バイキング・セラピューティクス・インコーポレイテッド 代謝及び肝臓障害の処置のための組成物及び方法
CN120359233A (zh) * 2022-11-24 2025-07-22 阿麦达斯制药美国有限责任公司 用于基于载体的疗法的坎普他汀类似物
CN118812653A (zh) * 2023-04-18 2024-10-22 成都奥达生物科技有限公司 一种长效坎普他汀化合物
CN119219741A (zh) * 2023-06-29 2024-12-31 刘晓蓉 新型补体抑制剂及其制备、应用和产品

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319897B1 (en) 1996-03-13 2001-11-20 John D. Lambris Peptides which inhibit complement activation
AU723268B2 (en) 1996-09-09 2000-08-24 Zealand Pharma A/S Improved solid-phase peptide synthesis and agent for use in such synthesis
WO1999013899A1 (en) 1997-09-17 1999-03-25 Trustees Of The University Of Pennsylvania Peptides and peptidomimetics for inhibiting complement activation
PT1549333E (pt) 2002-09-20 2012-01-03 Univ Pennsylvania Análogos de compstatina com actividade melhorada
EP2662089A3 (en) 2005-10-08 2014-02-19 Potentia Pharmaceuticals, Inc. Compstatin and analogs thereof for eye disorders
CN102977191B (zh) 2005-11-28 2016-08-10 宾夕法尼亚州大学理事会 有效的c3补体抑制素类似物
WO2008153963A1 (en) 2007-06-08 2008-12-18 The Trustees Of The University Of Pennsylvania Structure of compstatin-c3 complex and use for rational drug design
CA2813049A1 (en) * 2010-09-23 2012-03-29 The Trustees Of The University Of Pennsylvania Modified compstatin with improved stability and binding properties
RU2606120C2 (ru) * 2011-08-31 2017-01-10 Хантсман Эдванст Матириалз (Свитзеленд) Гмбх Способ пропитки реакторов с воздушным сердечником, подвергнутый пропитке реактор с воздушным сердечником и применение системы пропитки
CA2847862C (en) 2011-09-07 2021-01-12 The Trustees Of The University Of Pennsylvania Compstatin analogs with improved pharmacokinetic properties
US9512180B2 (en) 2012-12-19 2016-12-06 The Regents Of The University Of California Compstatin analogs
US10213476B2 (en) * 2014-03-17 2019-02-26 The Trustees Of The University Of Pennsylvania Compstatin analogs with improved potency and pharmacokinetic properties
RU2020128624A (ru) * 2018-02-27 2022-03-28 Зп Спв 3 К/С Аналоги компстатина и их медицинское применение
BR112022003760A2 (pt) * 2019-08-27 2022-05-31 Zp Spv 3 K/S Análogos de compstatina e seus usos médicos

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