JP2023538090A5 - - Google Patents
Info
- Publication number
- JP2023538090A5 JP2023538090A5 JP2023512197A JP2023512197A JP2023538090A5 JP 2023538090 A5 JP2023538090 A5 JP 2023538090A5 JP 2023512197 A JP2023512197 A JP 2023512197A JP 2023512197 A JP2023512197 A JP 2023512197A JP 2023538090 A5 JP2023538090 A5 JP 2023538090A5
- Authority
- JP
- Japan
- Prior art keywords
- lymphoma
- disease
- pharmaceutically acceptable
- stereoisomer
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010836243.4 | 2020-08-20 | ||
| CN202010836243.4A CN114075190A (zh) | 2020-08-20 | 2020-08-20 | 杂环类btk抑制剂 |
| PCT/CN2021/113538 WO2022037650A1 (en) | 2020-08-20 | 2021-08-19 | Bridged bicyclic compounds as btk inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023538090A JP2023538090A (ja) | 2023-09-06 |
| JP2023538090A5 true JP2023538090A5 (enExample) | 2024-08-26 |
| JP7669063B2 JP7669063B2 (ja) | 2025-04-28 |
Family
ID=80282666
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512198A Pending JP2023538091A (ja) | 2020-08-20 | 2021-08-19 | Ｂｔｋ阻害剤としての複素環式化合物 |
| JP2023512197A Active JP7669063B2 (ja) | 2020-08-20 | 2021-08-19 | Ｂｔｋ阻害剤としての架橋二環式化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512198A Pending JP2023538091A (ja) | 2020-08-20 | 2021-08-19 | Ｂｔｋ阻害剤としての複素環式化合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US12617788B2 (enExample) |
| EP (1) | EP4200283A4 (enExample) |
| JP (2) | JP2023538091A (enExample) |
| CN (2) | CN114075190A (enExample) |
| WO (2) | WO2022037650A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021180107A1 (en) * | 2020-03-12 | 2021-09-16 | Fochon Pharmaceuticals, Ltd. | Compounds useful as kinase inhibitors |
| CN114075190A (zh) | 2020-08-20 | 2022-02-22 | 北京诺诚健华医药科技有限公司 | 杂环类btk抑制剂 |
| CN114573586B (zh) * | 2020-11-28 | 2023-11-03 | 杭州和正医药有限公司 | 一种抑制布鲁顿酪氨酸激酶活性的多环化合物、药物组合物及其应用 |
| CN114634512B (zh) * | 2020-12-16 | 2023-11-14 | 江苏恒瑞医药股份有限公司 | 作为布鲁顿酪氨酸激酶抑制剂的化合物、其制备方法和医药应用 |
| EP4474377A4 (en) * | 2022-03-03 | 2025-07-30 | Shenzhen Targetrx Inc | Cycloalkyl or heterocyclyl substituted heteroaryl compound, and composition and use thereof |
| CN119241532A (zh) * | 2023-07-03 | 2025-01-03 | 深圳市塔吉瑞生物医药有限公司 | 1H-吡唑并[4,3-c]吡啶化合物及其组合物及用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2548877A1 (en) * | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| SG11201605417QA (en) * | 2014-02-03 | 2016-08-30 | Cadila Healthcare Ltd | Heterocyclic compounds |
| GB201410430D0 (en) * | 2014-06-11 | 2014-07-23 | Redx Pharma Ltd | Compounds |
| WO2016019237A2 (en) * | 2014-07-31 | 2016-02-04 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
| WO2016106624A1 (en) * | 2014-12-31 | 2016-07-07 | Merck Sharp & Dohme Corp. | Tertiary alcohol imidazopyrazine btk inhibitors |
| WO2016106623A1 (en) | 2014-12-31 | 2016-07-07 | Merck Sharp & Dohme Corp. | Benzamide imidazopyrazine btk inhibitors |
| WO2016106652A1 (en) * | 2014-12-31 | 2016-07-07 | Merck Sharp & Dohme Corp. | Biarylether imidazopyrazine btk inhibitors |
| US10611766B2 (en) * | 2015-09-16 | 2020-04-07 | Loxo Oncology Inc. | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer |
| ES2856248T3 (es) * | 2016-12-21 | 2021-09-27 | Acerta Pharma Bv | Inhibidores de imidazopirazina de la tirosina quinasa de Bruton |
| WO2020015735A1 (zh) * | 2018-07-20 | 2020-01-23 | 正大天晴药业集团股份有限公司 | 布鲁顿酪氨酸激酶抑制剂 |
| CN110964016B (zh) * | 2018-09-29 | 2021-05-28 | 南京药捷安康生物科技有限公司 | 氨基降茨烷衍生物及其制备方法与应用 |
| CA3126940A1 (en) * | 2019-01-18 | 2020-07-23 | Xibin Liao | Bruton's tyrosine kinase inhibitors |
| WO2021180107A1 (en) * | 2020-03-12 | 2021-09-16 | Fochon Pharmaceuticals, Ltd. | Compounds useful as kinase inhibitors |
| AU2020436612A1 (en) | 2020-03-16 | 2022-09-01 | Flash Therapeutics, Llc | Compounds for treating or inhibiting recurrence of acute myeloid leukemia |
| CN114075190A (zh) * | 2020-08-20 | 2022-02-22 | 北京诺诚健华医药科技有限公司 | 杂环类btk抑制剂 |
-
2020
- 2020-08-20 CN CN202010836243.4A patent/CN114075190A/zh active Pending
-
2021
- 2021-08-19 JP JP2023512198A patent/JP2023538091A/ja active Pending
- 2021-08-19 WO PCT/CN2021/113538 patent/WO2022037650A1/en not_active Ceased
- 2021-08-19 CN CN202180050894.3A patent/CN116670119B/zh active Active
- 2021-08-19 EP EP21857742.7A patent/EP4200283A4/en not_active Withdrawn
- 2021-08-19 JP JP2023512197A patent/JP7669063B2/ja active Active
- 2021-08-19 WO PCT/CN2021/113535 patent/WO2022037649A1/en not_active Ceased
-
2023
- 2023-02-15 US US18/169,408 patent/US12617788B2/en active Active
- 2023-02-15 US US18/169,423 patent/US20230192691A1/en not_active Abandoned
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