JP2023536466A5 - - Google Patents

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Publication number
JP2023536466A5
JP2023536466A5 JP2023505927A JP2023505927A JP2023536466A5 JP 2023536466 A5 JP2023536466 A5 JP 2023536466A5 JP 2023505927 A JP2023505927 A JP 2023505927A JP 2023505927 A JP2023505927 A JP 2023505927A JP 2023536466 A5 JP2023536466 A5 JP 2023536466A5
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JP
Japan
Prior art keywords
peptide
sequence number
seq
composition according
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023505927A
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English (en)
Japanese (ja)
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JP2023536466A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/043373 external-priority patent/WO2022026496A2/en
Publication of JP2023536466A publication Critical patent/JP2023536466A/ja
Publication of JP2023536466A5 publication Critical patent/JP2023536466A5/ja
Pending legal-status Critical Current

Links

JP2023505927A 2020-07-31 2021-07-28 Lag3結合ペプチド Pending JP2023536466A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063059225P 2020-07-31 2020-07-31
US63/059,225 2020-07-31
PCT/US2021/043373 WO2022026496A2 (en) 2020-07-31 2021-07-28 Lag3 binding peptides

Publications (2)

Publication Number Publication Date
JP2023536466A JP2023536466A (ja) 2023-08-25
JP2023536466A5 true JP2023536466A5 (enExample) 2024-08-05

Family

ID=77726513

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023505927A Pending JP2023536466A (ja) 2020-07-31 2021-07-28 Lag3結合ペプチド

Country Status (6)

Country Link
US (1) US11578102B2 (enExample)
EP (1) EP4188947A2 (enExample)
JP (1) JP2023536466A (enExample)
AU (1) AU2021316230A1 (enExample)
CA (1) CA3189692A1 (enExample)
WO (1) WO2022026496A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025193569A1 (en) * 2024-03-11 2025-09-18 Bristol-Myers Squibb Company Macrocyclic peptides useful as immunomodulators
WO2025193571A1 (en) * 2024-03-11 2025-09-18 Bristol-Myers Squibb Company Macrocyclic peptides useful as immunomodulators
WO2025193573A1 (en) * 2024-03-11 2025-09-18 Bristol-Myers Squibb Company Macrocyclic peptides useful as immunomodulators

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002513811A (ja) 1998-05-06 2002-05-14 ファルマシア・アンド・アップジョン・カンパニー 非−ヒト脊椎動物への、非−ヒト脊椎動物のペプチドホルモンまたはサイトカインをコードする裸のdnaまたは裸のrnaの導入
CA2541006C (en) 2003-10-03 2015-02-17 Brigham And Women's Hospital Tim-3 polypeptides
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
US20090074976A1 (en) 2007-09-14 2009-03-19 Freking Anthony J Method of reducing mottle and streak defects in coatings
EP2201120B1 (en) 2007-09-21 2013-12-25 Cadila Healthcare Limited Gcsf fusion protein systems suitable for high expression of peptides
MX374075B (es) 2010-03-26 2025-03-05 Dartmouth College Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos.
WO2011125015A2 (en) * 2010-04-05 2011-10-13 Bar-Ilan University Protease-activatable pore-forming polypeptides
US9845362B2 (en) 2010-10-08 2017-12-19 The University Of North Carolina At Charlotte Compositions comprising chimeric antigen receptors, T cells comprising the same, and methods of using the same
US20130267515A1 (en) 2010-10-26 2013-10-10 Alberta Health Services Combination comprising an atp analog and an adenosine receptor antagonist or a nucleobase/nucleoside analog for the treatment of cancer
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
WO2012116714A1 (en) 2011-03-02 2012-09-07 Curevac Gmbh Vaccination in elderly patients
EP2583975A1 (en) 2011-10-21 2013-04-24 Heinrich-Heine-Universität Düsseldorf Agents and methods for the expression and secretion of peptides and proteins
US9381244B2 (en) 2012-09-07 2016-07-05 King's College London VISTA modulators for diagnosis and treatment of cancer
US20150250837A1 (en) 2012-09-20 2015-09-10 Morningside Technology Ventures Ltd. Oncolytic virus encoding pd-1 binding agents and uses of the same
PL2904011T3 (pl) 2012-10-02 2018-01-31 Bristol Myers Squibb Co Połączenie przeciwciał anty-kir i przeciwciał anty-pd-1 w leczeniu raka
US9974845B2 (en) 2013-02-22 2018-05-22 Curevac Ag Combination of vaccination and inhibition of the PD-1 pathway
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
EP2792686A1 (en) 2013-04-17 2014-10-22 Heinrich-Heine-Universität Düsseldorf Methods for the expression of peptides and proteins
CN104072615B (zh) 2014-01-26 2016-08-24 中国人民解放军军事医学科学院基础医学研究所 一种能阻断Tim-3信号通路的人Tim-3融合蛋白
HUE045065T2 (hu) 2014-01-31 2019-12-30 Novartis Ag TIM-3 antitest molekulák és felhasználásaik
SG11201606428UA (en) 2014-02-04 2016-09-29 Incyte Corp Combination of a pd-1 antagonist and an ido1 inhibitor for treating cancer
US10899840B2 (en) 2014-02-04 2021-01-26 Pfizer Inc. Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
BR102014014502B1 (pt) 2014-06-13 2020-09-15 Ouro Fino Saúde Animal Ltda Vetor de expressão
RU2696312C2 (ru) 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
ES2833425T3 (es) 2014-07-16 2021-06-15 Roussy Inst Gustave Combinación de virus oncolítico con moduladores de punto de control inmunitario
JO3663B1 (ar) * 2014-08-19 2020-08-27 Merck Sharp & Dohme الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
US10695426B2 (en) 2014-08-25 2020-06-30 Pfizer Inc. Combination of a PD-1 antagonist and an ALK inhibitor for treating cancer
US9710278B2 (en) 2014-09-30 2017-07-18 International Business Machines Corporation Optimizing grouping of instructions
BR112017007765B1 (pt) 2014-10-14 2023-10-03 Halozyme, Inc Composições de adenosina deaminase-2 (ada2), variantes do mesmo e métodos de usar o mesmo
GB201504502D0 (en) 2015-03-17 2015-04-29 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
TWI756187B (zh) 2015-10-09 2022-03-01 美商再生元醫藥公司 抗lag3抗體及其用途
US9957325B2 (en) 2015-10-13 2018-05-01 Formurex, Inc. Synthetic antibody mimic peptides
CN105504018B (zh) 2016-01-13 2019-01-04 郑州大学 Lag-3亲和肽n13、制备方法及其应用
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
AU2017290828A1 (en) 2016-06-30 2019-01-24 Virogin Biotech Canada Ltd Pseudotyped oncolytic viral delivery of therapeutic polypeptides
WO2018039147A1 (en) * 2016-08-23 2018-03-01 The Johns Hopkins University THERAPEUTIC USES OF LAG3 THE α-SYNUCLEIN TRANSMISSION RECEPTOR
LT4445958T (lt) * 2018-10-19 2025-12-10 Bristol-Myers Squibb Company Kompleksinė terapija, skirta melanomai gydyti
WO2020237050A1 (en) 2019-05-22 2020-11-26 Leidos, Inc. Lag3 binding peptides
CA3185657A1 (en) 2020-06-04 2021-12-09 Leidos, Inc. Immunomodulatory compounds

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