JP2023535345A5 - - Google Patents
Info
- Publication number
- JP2023535345A5 JP2023535345A5 JP2023502801A JP2023502801A JP2023535345A5 JP 2023535345 A5 JP2023535345 A5 JP 2023535345A5 JP 2023502801 A JP2023502801 A JP 2023502801A JP 2023502801 A JP2023502801 A JP 2023502801A JP 2023535345 A5 JP2023535345 A5 JP 2023535345A5
- Authority
- JP
- Japan
- Prior art keywords
- camel
- gene
- human
- gene fragments
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063051180P | 2020-07-13 | 2020-07-13 | |
| US63/051,180 | 2020-07-13 | ||
| US202063076096P | 2020-09-09 | 2020-09-09 | |
| US63/076,096 | 2020-09-09 | ||
| PCT/CA2021/050951 WO2022011457A1 (en) | 2020-07-13 | 2021-07-12 | Transgenic animals expressing heavy chain antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023535345A JP2023535345A (ja) | 2023-08-17 |
| JP2023535345A5 true JP2023535345A5 (enExample) | 2024-07-24 |
Family
ID=79555903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023502801A Pending JP2023535345A (ja) | 2020-07-13 | 2021-07-12 | 重鎖抗体を発現するトランスジェニック動物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230270086A1 (enExample) |
| EP (1) | EP4179095A4 (enExample) |
| JP (1) | JP2023535345A (enExample) |
| CN (1) | CN116193985A (enExample) |
| CA (1) | CA3171186A1 (enExample) |
| TW (1) | TWI908828B (enExample) |
| WO (1) | WO2022011457A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025245358A1 (en) * | 2024-05-22 | 2025-11-27 | New York University | Genetically modified non-human animals producing heavy chain-only antibodies and methods of use |
| US20250361309A1 (en) | 2024-05-24 | 2025-11-27 | Regeneron Pharmaceuticals, Inc. | Tumor-targeted split il12 receptor agonists |
| WO2025255480A1 (en) | 2024-06-07 | 2025-12-11 | Regeneron Pharmaceuticals, Inc. | Tetravalent multispecific binding molecules and methods of use thereof |
| WO2025255452A2 (en) | 2024-06-07 | 2025-12-11 | Regeneron Pharmaceuticals, Inc. | Antigen-binding molecules that bind to aav particles and uses thereof |
| WO2026039791A1 (en) | 2024-08-16 | 2026-02-19 | Regeneron Pharmaceuticals, Inc. | Tumor-targeted split il2 receptor agonists |
| WO2026075989A1 (en) | 2024-10-01 | 2026-04-09 | Regeneron Pharmaceuticals, Inc. | Engineered igg molecules and methods of use thereof |
| WO2026076013A1 (en) | 2024-10-01 | 2026-04-09 | Regeneron Pharmaceuticals, Inc. | Tumor-targeted il2 receptor agonists and multispecific t-cell engagers |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0110029D0 (en) * | 2001-04-24 | 2001-06-13 | Grosveld Frank | Transgenic animal |
| KR101151957B1 (ko) * | 2004-07-22 | 2012-06-01 | 로저 킹돈 크레이그 | 결합 분자 |
| AU2007219159B8 (en) * | 2006-01-25 | 2012-06-28 | Roger Kingdon Craig | Generation of heavy-chain only antibodies in transgenic animals |
| ES2724975T3 (es) * | 2009-12-10 | 2019-09-18 | Regeneron Pharma | Ratones que producen anticuerpos de cadena pesada |
| SG10201605675WA (en) * | 2011-12-20 | 2016-09-29 | Regeneron Pharma | Humanized light chain mice |
| CA3124228C (en) * | 2014-03-21 | 2024-05-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
| CN109906030B (zh) * | 2016-11-04 | 2022-03-18 | 安健基因公司 | 用于产生仅重链抗体的经基因修饰的非人动物和方法 |
| EP3332637A1 (en) * | 2016-12-09 | 2018-06-13 | Universitätsklinikum Hamburg-Eppendorf | Vhh-containing heavy chain antibody and production thereof |
| CA3102122A1 (en) * | 2018-06-13 | 2019-12-19 | Crystal Bioscience Inc. | Transgenic chicken with functionally deleted igy ch1 coding sequence |
| JP7822400B2 (ja) * | 2020-12-09 | 2026-03-02 | トリアンニ，インコーポレーテッド | 重鎖のみ抗体 |
-
2021
- 2021-07-12 JP JP2023502801A patent/JP2023535345A/ja active Pending
- 2021-07-12 US US18/015,304 patent/US20230270086A1/en active Pending
- 2021-07-12 EP EP21843204.5A patent/EP4179095A4/en active Pending
- 2021-07-12 CA CA3171186A patent/CA3171186A1/en active Pending
- 2021-07-12 WO PCT/CA2021/050951 patent/WO2022011457A1/en not_active Ceased
- 2021-07-12 CN CN202180060845.8A patent/CN116193985A/zh active Pending
- 2021-07-13 TW TW110125742A patent/TWI908828B/zh active
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