JP2024518435A5 - - Google Patents

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Publication number
JP2024518435A5
JP2024518435A5 JP2023568507A JP2023568507A JP2024518435A5 JP 2024518435 A5 JP2024518435 A5 JP 2024518435A5 JP 2023568507 A JP2023568507 A JP 2023568507A JP 2023568507 A JP2023568507 A JP 2023568507A JP 2024518435 A5 JP2024518435 A5 JP 2024518435A5
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JP
Japan
Prior art keywords
human animal
human
domain
animal according
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023568507A
Other languages
English (en)
Japanese (ja)
Other versions
JP7799706B2 (ja
JP2024518435A (ja
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Priority claimed from PCT/US2022/027946 external-priority patent/WO2022235988A1/en
Publication of JP2024518435A publication Critical patent/JP2024518435A/ja
Publication of JP2024518435A5 publication Critical patent/JP2024518435A5/ja
Priority to JP2025283504A priority Critical patent/JP2026062865A/ja
Application granted granted Critical
Publication of JP7799706B2 publication Critical patent/JP7799706B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023568507A 2021-05-05 2022-05-05 抗体を産生するための組換え非ヒト動物 Active JP7799706B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025283504A JP2026062865A (ja) 2021-05-05 2025-12-26 抗体を産生するための組換え非ヒト動物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163184384P 2021-05-05 2021-05-05
US202163184385P 2021-05-05 2021-05-05
US63/184,385 2021-05-05
US63/184,384 2021-05-05
PCT/US2022/027946 WO2022235988A1 (en) 2021-05-05 2022-05-05 Engineered non-human animals for producing antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025283504A Division JP2026062865A (ja) 2021-05-05 2025-12-26 抗体を産生するための組換え非ヒト動物

Publications (3)

Publication Number Publication Date
JP2024518435A JP2024518435A (ja) 2024-05-01
JP2024518435A5 true JP2024518435A5 (enExample) 2024-05-30
JP7799706B2 JP7799706B2 (ja) 2026-01-15

Family

ID=83932298

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023568507A Active JP7799706B2 (ja) 2021-05-05 2022-05-05 抗体を産生するための組換え非ヒト動物
JP2025283504A Pending JP2026062865A (ja) 2021-05-05 2025-12-26 抗体を産生するための組換え非ヒト動物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025283504A Pending JP2026062865A (ja) 2021-05-05 2025-12-26 抗体を産生するための組換え非ヒト動物

Country Status (5)

Country Link
US (1) US20240251767A1 (enExample)
EP (1) EP4333614A4 (enExample)
JP (2) JP7799706B2 (enExample)
CA (1) CA3218564A1 (enExample)
WO (1) WO2022235988A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250108092A (ko) * 2024-01-02 2025-07-15 젬파마테크 컴퍼니 리미티드 인간화 항체를 생성하는 동물 모델 및 그 제작 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066718A (en) * 1992-09-25 2000-05-23 Novartis Corporation Reshaped monoclonal antibodies against an immunoglobulin isotype
US7132282B2 (en) * 2004-01-30 2006-11-07 Ingenious Targeting Inc. Genetic modification of C57 mice
KR101151957B1 (ko) * 2004-07-22 2012-06-01 로저 킹돈 크레이그 결합 분자
WO2006090385A2 (en) * 2005-02-22 2006-08-31 Ramot At Tel-Aviv University Ltd. Protease inhibitors and method of screening thereof
EP2277916A3 (en) * 2005-07-28 2011-04-27 Novartis AG Use of antibody to M-CSF
ES2724975T3 (es) * 2009-12-10 2019-09-18 Regeneron Pharma Ratones que producen anticuerpos de cadena pesada
GB2502127A (en) * 2012-05-17 2013-11-20 Kymab Ltd Multivalent antibodies and in vivo methods for their production
CA2884859C (en) * 2012-09-12 2024-06-18 Duke University Hiv-1 antibody evolution immunogens
CA3124228C (en) * 2014-03-21 2024-05-14 Regeneron Pharmaceuticals, Inc. Non-human animals that make single domain binding proteins
CN109906030B (zh) * 2016-11-04 2022-03-18 安健基因公司 用于产生仅重链抗体的经基因修饰的非人动物和方法
GB2561352B (en) * 2017-04-10 2023-01-18 Genome Res Ltd Animal models and therapeutic molecules
CN108486125B (zh) * 2018-03-27 2024-01-05 重庆金迈博生物科技有限公司 一种核酸分子及其在制备人源单域抗体中的应用

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