JP2023535025A5 - - Google Patents

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Publication number
JP2023535025A5
JP2023535025A5 JP2023504286A JP2023504286A JP2023535025A5 JP 2023535025 A5 JP2023535025 A5 JP 2023535025A5 JP 2023504286 A JP2023504286 A JP 2023504286A JP 2023504286 A JP2023504286 A JP 2023504286A JP 2023535025 A5 JP2023535025 A5 JP 2023535025A5
Authority
JP
Japan
Prior art keywords
nucleic acid
recognition helix
transactivator
dna
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023504286A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023535025A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/042949 external-priority patent/WO2022020706A1/en
Publication of JP2023535025A publication Critical patent/JP2023535025A/ja
Publication of JP2023535025A5 publication Critical patent/JP2023535025A5/ja
Pending legal-status Critical Current

Links

JP2023504286A 2020-07-24 2021-07-23 Dna結合ドメイントランス活性化因子およびその使用 Pending JP2023535025A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063056528P 2020-07-24 2020-07-24
US63/056,528 2020-07-24
PCT/US2021/042949 WO2022020706A1 (en) 2020-07-24 2021-07-23 Dna-binding domain transactivators and uses thereof

Publications (2)

Publication Number Publication Date
JP2023535025A JP2023535025A (ja) 2023-08-15
JP2023535025A5 true JP2023535025A5 (https=) 2024-07-31

Family

ID=79728976

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023504286A Pending JP2023535025A (ja) 2020-07-24 2021-07-23 Dna結合ドメイントランス活性化因子およびその使用

Country Status (6)

Country Link
US (1) US20230279405A1 (https=)
EP (1) EP4185303A4 (https=)
JP (1) JP2023535025A (https=)
AR (1) AR123041A1 (https=)
TW (1) TW202221119A (https=)
WO (1) WO2022020706A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7624728B2 (ja) 2019-02-25 2025-01-31 ユニバーシティ オブ マサチューセッツ Dna結合ドメイントランスアクチベーター及びその使用
WO2024238662A2 (en) * 2023-05-17 2024-11-21 University Of Washington Synthetic nuclear localization signals and methods of their use
WO2025250686A1 (en) * 2024-05-28 2025-12-04 The Regents Of The University Of California Methods and systems for parallel spatially resolved single-cell profiling

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007061759A1 (en) * 2005-11-18 2007-05-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Delayed expression vectors
AU2010273220B2 (en) * 2009-07-13 2015-10-15 President And Fellows Of Harvard College Bifunctional stapled polypeptides and uses thereof
JP2018513681A (ja) * 2015-03-31 2018-05-31 エクセリゲン サイエンティフィック, インコーポレイテッドExeligen Scientific, Inc. 細胞または生物のゲノムへのDNA配列の標的化組み込みのためのCas9レトロウイルスインテグラーゼおよびCas9レコンビナーゼ系
US20190127713A1 (en) * 2016-04-13 2019-05-02 Duke University Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
CA3035534A1 (en) * 2016-09-07 2018-03-15 Sangamo Therapeutics, Inc. Modulation of liver genes
JP2018088888A (ja) * 2016-12-06 2018-06-14 国立研究開発法人理化学研究所 Scn1a遺伝子の発現増強法
MX2019011772A (es) * 2017-04-03 2020-01-09 Encoded Therapeutics Inc Expresion transgenica selectiva de tejidos.
WO2018204764A1 (en) * 2017-05-05 2018-11-08 Camp4 Therapeutics Corporation Identification and targeted modulation of gene signaling networks
EP3717505A4 (en) * 2017-12-01 2021-12-01 Encoded Therapeutics, Inc. GENENICALLY MODIFIED DNA-BINDING PROTEINS
CA3096407A1 (en) * 2018-04-09 2019-10-17 Allen Institute Rescuing voltage-gated sodium channel function in inhibitory neurons
WO2020097121A1 (en) * 2018-11-05 2020-05-14 Allen Institute Artificial expression constructs for selectively modulating gene expression in excitatory cortical neurons
JP7624728B2 (ja) * 2019-02-25 2025-01-31 ユニバーシティ オブ マサチューセッツ Dna結合ドメイントランスアクチベーター及びその使用

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