JP2023534528A5 - - Google Patents
Info
- Publication number
- JP2023534528A5 JP2023534528A5 JP2023503463A JP2023503463A JP2023534528A5 JP 2023534528 A5 JP2023534528 A5 JP 2023534528A5 JP 2023503463 A JP2023503463 A JP 2023503463A JP 2023503463 A JP2023503463 A JP 2023503463A JP 2023534528 A5 JP2023534528 A5 JP 2023534528A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- group
- cancer
- general formula
- meso
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010696995 | 2020-07-20 | ||
| CN202010696995.5 | 2020-07-20 | ||
| CN202010783483.2 | 2020-08-06 | ||
| CN202010783483 | 2020-08-06 | ||
| CN202011223930 | 2020-11-05 | ||
| CN202011223930.5 | 2020-11-05 | ||
| CN202110410441.9 | 2021-04-16 | ||
| CN202110410441 | 2021-04-16 | ||
| PCT/CN2021/107297 WO2022017365A1 (zh) | 2020-07-20 | 2021-07-20 | 含硫异吲哚啉类衍生物、其制备方法及其在医药上的应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023534528A JP2023534528A (ja) | 2023-08-09 |
| JP2023534528A5 true JP2023534528A5 (https=) | 2024-07-11 |
Family
ID=79728998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023503463A Pending JP2023534528A (ja) | 2020-07-20 | 2021-07-20 | 硫黄含有イソインドリン系誘導体、その調製方法及びその医薬的応用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230257366A1 (https=) |
| EP (1) | EP4183781A4 (https=) |
| JP (1) | JP2023534528A (https=) |
| KR (1) | KR20230042057A (https=) |
| CN (3) | CN120004859A (https=) |
| AU (1) | AU2021314401A1 (https=) |
| BR (1) | BR112023000817A2 (https=) |
| CA (1) | CA3184711A1 (https=) |
| MX (1) | MX2023000868A (https=) |
| WO (1) | WO2022017365A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023210002A1 (en) * | 2022-01-19 | 2024-08-22 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Crystalline form of sulfur-containing isoindoline derivative |
| CN116462660A (zh) * | 2022-01-19 | 2023-07-21 | 江苏恒瑞医药股份有限公司 | 一种异喹啉酮类化合物的盐及其晶型 |
| EP4584259A1 (en) | 2022-09-09 | 2025-07-16 | Innovo Therapeutics, Inc. | Ck1alpha and dual ck1alpha / gspt1 degrading compounds |
| WO2025063888A1 (en) | 2023-09-19 | 2025-03-27 | Kancure Pte. Ltd. | Survivin-targeted compounds |
| WO2025179161A1 (en) | 2024-02-21 | 2025-08-28 | Innovo Therapeutics, Inc. | Protein degrading compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050143344A1 (en) | 2003-12-30 | 2005-06-30 | Zeldis Jerome B. | Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases |
| ZA200704890B (en) | 2004-11-23 | 2008-09-25 | Celgene Corp | Methods and compositions using immunomodulatory compounds for treatment and management of central nervous system injury |
| MX2009010082A (es) * | 2007-03-20 | 2009-10-19 | Celgene Corp | Derivados y composiciones que comprenden isoindolina 4'-o-sustituida y metodos para utilizar la misma. |
| PL3202460T3 (pl) * | 2010-02-11 | 2019-12-31 | Celgene Corporation | Pochodne arylometoksyizoindoliny i zawierające je kompozycje oraz sposoby ich zastosowania |
| SG11201808728QA (en) * | 2016-04-06 | 2018-11-29 | Univ Michigan Regents | Mdm2 protein degraders |
| EP3381474A1 (en) * | 2017-03-27 | 2018-10-03 | Alfasigma S.p.A. | Histone deacetylase inhibitors-based antibody drug conjugates (adcs) and use in therapy |
| EP4467143B1 (en) * | 2017-07-10 | 2026-03-11 | Celgene Corporation | Method for preparing 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-l-yl)-3-fluorobenzonitrile |
| US10513515B2 (en) | 2017-08-25 | 2019-12-24 | Biotheryx, Inc. | Ether compounds and uses thereof |
| KR102718800B1 (ko) * | 2018-05-23 | 2024-10-18 | 셀진 코포레이션 | 다발성 골수종의 치료 및 4-(4-(4-(((2-(2,6-디옥소피페리딘-3-일)-1-옥소이소인돌린-4-일)옥시)메틸)벤질)피페라진-1-일)-3-플루오로벤조니트릴에 대한 바이오마커의 용도 |
| AU2019348094B2 (en) | 2018-09-30 | 2022-12-22 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Isoindoline compound, preparation method, pharmaceutical composition and use thereof |
| SG11202107439XA (en) * | 2019-01-09 | 2021-08-30 | Celgene Corp | Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same |
| WO2021055756A1 (en) * | 2019-09-19 | 2021-03-25 | The Regents Of The University Of Michigan | Spirocyclic androgen receptor protein degraders |
| DK4178548T3 (da) * | 2020-07-07 | 2024-08-19 | Celgene Corp | Farmaceutiske sammensætninger omfattende (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-1-YL)-3-FLUORBENZONITRIL |
-
2021
- 2021-07-20 BR BR112023000817A patent/BR112023000817A2/pt unknown
- 2021-07-20 EP EP21847148.0A patent/EP4183781A4/en active Pending
- 2021-07-20 CN CN202510100913.9A patent/CN120004859A/zh active Pending
- 2021-07-20 JP JP2023503463A patent/JP2023534528A/ja active Pending
- 2021-07-20 CN CN202510102009.1A patent/CN120004860A/zh active Pending
- 2021-07-20 MX MX2023000868A patent/MX2023000868A/es unknown
- 2021-07-20 KR KR1020237005618A patent/KR20230042057A/ko active Pending
- 2021-07-20 WO PCT/CN2021/107297 patent/WO2022017365A1/zh not_active Ceased
- 2021-07-20 CN CN202180041057.4A patent/CN115916768B/zh active Active
- 2021-07-20 AU AU2021314401A patent/AU2021314401A1/en active Pending
- 2021-07-20 CA CA3184711A patent/CA3184711A1/en active Pending
- 2021-07-20 US US18/017,388 patent/US20230257366A1/en active Pending
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