JP2023533932A5 - - Google Patents
Info
- Publication number
- JP2023533932A5 JP2023533932A5 JP2022581707A JP2022581707A JP2023533932A5 JP 2023533932 A5 JP2023533932 A5 JP 2023533932A5 JP 2022581707 A JP2022581707 A JP 2022581707A JP 2022581707 A JP2022581707 A JP 2022581707A JP 2023533932 A5 JP2023533932 A5 JP 2023533932A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- stereoisomer
- carbonnitrile
- fluoropyrrolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20382606.0 | 2020-07-07 | ||
| EP20382606 | 2020-07-07 | ||
| PCT/EP2021/068577 WO2022008477A1 (en) | 2020-07-07 | 2021-07-06 | 1-[1-(4-benzyloxy-3,5-difluoro-benzoyl)-4-fluoro-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023533932A JP2023533932A (ja) | 2023-08-07 |
| JP2023533932A5 true JP2023533932A5 (enExample) | 2024-07-01 |
| JP7628716B2 JP7628716B2 (ja) | 2025-02-12 |
Family
ID=71607883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022581707A Active JP7628716B2 (ja) | 2020-07-07 | 2021-07-06 | １－［１－（４－ベンジルオキシ－３，５－ジフルオロ－ベンゾイル）－４－フルオロ－ピロリジン－２－カルボニル］－ピロリジン－２－カルボニトリル |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US12459891B2 (enExample) |
| EP (1) | EP4178945B1 (enExample) |
| JP (1) | JP7628716B2 (enExample) |
| KR (1) | KR20230035604A (enExample) |
| CN (1) | CN117545738A (enExample) |
| AU (1) | AU2021303440A1 (enExample) |
| BR (1) | BR112023000335A2 (enExample) |
| CA (1) | CA3185064A1 (enExample) |
| ES (1) | ES2997164T3 (enExample) |
| HR (1) | HRP20241527T1 (enExample) |
| HU (1) | HUE068953T2 (enExample) |
| IL (1) | IL299035B1 (enExample) |
| MA (1) | MA60250B1 (enExample) |
| MX (1) | MX2023000261A (enExample) |
| RS (1) | RS66215B1 (enExample) |
| SM (1) | SMT202400460T1 (enExample) |
| TW (1) | TWI893162B (enExample) |
| WO (1) | WO2022008477A1 (enExample) |
| ZA (1) | ZA202213708B (enExample) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6159938A (en) | 1994-11-21 | 2000-12-12 | Cortech, Inc. | Serine protease inhibitors comprising α-keto heterocycles |
| DE19603510A1 (de) | 1996-02-01 | 1997-08-07 | Knoell Hans Forschung Ev | Die Verwendung von Terrecyclolsäure A und Terrecyclolsäure A-Derivate als neue Inhibitoren der humanen Prolyl-Oligopeptidase |
| FI20011466A0 (fi) | 2001-07-04 | 2001-07-04 | Orion Corp | Prolyylioligopeptidaasia inhiboivaa aktiivisuutta omaavia yhdisteitä, niiden valmistusmenetelmiä ja käyttö |
| FI20030014A0 (fi) | 2003-01-03 | 2003-01-03 | Orion Corp | Prolyylioligopeptidaasia inhiboivaa aktiivisuutta omaavia yhdisteitä |
| FI20031018A0 (fi) | 2003-07-04 | 2003-07-04 | Orion Corp | Parannus aivovammasta toipumiseen |
| WO2005027934A1 (ja) | 2003-09-24 | 2005-03-31 | Nippon Kayaku Kabushiki Kaisha | プロリルオリゴペプチダーゼ阻害剤 |
| US7667044B2 (en) | 2003-11-03 | 2010-02-23 | Probiodrug Ag | Compounds for the treatment of neurological disorders |
| ES2302473B1 (es) | 2006-12-22 | 2009-06-12 | Universidad De Barcelona | Agente terapeutico para el tratamiento del desorden afectivo bipolar en mamiferos. |
| EP2730571A1 (en) * | 2012-11-12 | 2014-05-14 | Universitat De Barcelona | 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives |
-
2021
- 2021-07-06 AU AU2021303440A patent/AU2021303440A1/en active Pending
- 2021-07-06 RS RS20241253A patent/RS66215B1/sr unknown
- 2021-07-06 WO PCT/EP2021/068577 patent/WO2022008477A1/en not_active Ceased
- 2021-07-06 HR HRP20241527TT patent/HRP20241527T1/hr unknown
- 2021-07-06 MX MX2023000261A patent/MX2023000261A/es unknown
- 2021-07-06 TW TW110124773A patent/TWI893162B/zh active
- 2021-07-06 EP EP21739678.7A patent/EP4178945B1/en active Active
- 2021-07-06 HU HUE21739678A patent/HUE068953T2/hu unknown
- 2021-07-06 JP JP2022581707A patent/JP7628716B2/ja active Active
- 2021-07-06 CA CA3185064A patent/CA3185064A1/en active Pending
- 2021-07-06 SM SM20240460T patent/SMT202400460T1/it unknown
- 2021-07-06 CN CN202180047448.7A patent/CN117545738A/zh active Pending
- 2021-07-06 US US18/004,658 patent/US12459891B2/en active Active
- 2021-07-06 MA MA60250A patent/MA60250B1/fr unknown
- 2021-07-06 ES ES21739678T patent/ES2997164T3/es active Active
- 2021-07-06 BR BR112023000335A patent/BR112023000335A2/pt unknown
- 2021-07-06 KR KR1020237003988A patent/KR20230035604A/ko active Pending
-
2022
- 2022-12-12 IL IL299035A patent/IL299035B1/en unknown
- 2022-12-19 ZA ZA2022/13708A patent/ZA202213708B/en unknown
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