JP2023529099A5 - - Google Patents
Info
- Publication number
- JP2023529099A5 JP2023529099A5 JP2022573579A JP2022573579A JP2023529099A5 JP 2023529099 A5 JP2023529099 A5 JP 2023529099A5 JP 2022573579 A JP2022573579 A JP 2022573579A JP 2022573579 A JP2022573579 A JP 2022573579A JP 2023529099 A5 JP2023529099 A5 JP 2023529099A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- aryl
- heteroalkyl
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020092941 | 2020-05-28 | ||
| CNPCT/CN2020/092941 | 2020-05-28 | ||
| CNPCT/CN2021/081554 | 2021-03-18 | ||
| CN2021081554 | 2021-03-18 | ||
| PCT/CN2021/096782 WO2021239117A1 (en) | 2020-05-28 | 2021-05-28 | Modified proteins and protein degraders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023529099A JP2023529099A (ja) | 2023-07-07 |
| JP2023529099A5 true JP2023529099A5 (enExample) | 2024-06-04 |
| JP7898388B2 JP7898388B2 (ja) | 2026-07-31 |
Family
ID=78722770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022573579A Active JP7898388B2 (ja) | 2020-05-28 | 2021-05-28 | 修飾タンパク質およびタンパク質分解誘導薬 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20230057177A1 (enExample) |
| EP (1) | EP4157888A4 (enExample) |
| JP (1) | JP7898388B2 (enExample) |
| CN (1) | CN116472292A (enExample) |
| WO (1) | WO2021239117A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12022551379A1 (en) | 2019-12-06 | 2023-05-03 | Vertex Pharma | Substituted tetrahydrofurans as modulators of sodium channels |
| WO2022218239A1 (zh) * | 2021-04-12 | 2022-10-20 | 杜心赟 | 新型噻唑类化合物及其制备方法和用途 |
| SI4347031T1 (sl) | 2021-06-04 | 2026-01-30 | Vertex Pharmaceuticals Incorporated | N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov |
| AU2022362494A1 (en) * | 2021-10-14 | 2024-05-23 | Cullgen (Shanghai), Inc. | Modified proteins and protein degraders |
| US20260209211A1 (en) * | 2022-12-16 | 2026-07-23 | Adlai Nortye Biopharma Co., Ltd. | Cyclin k degrader and use thereof |
| CN121358732A (zh) * | 2023-03-07 | 2026-01-16 | 睿跃生物科技有限公司 | 治疗癌症的化合物和方法 |
| WO2025054361A1 (en) * | 2023-09-05 | 2025-03-13 | Apellis Pharmaceuticals, Inc. | Complement inhibition |
| WO2026128761A1 (en) | 2024-12-11 | 2026-06-18 | Nexo Therapeutics, Inc. | Covalent p300 inhibitor compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11008372B2 (en) * | 2015-11-07 | 2021-05-18 | Board Of Regents, The University Of Texas System | Targeting proteins for degradation |
| GB201520583D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| WO2018144832A1 (en) * | 2017-02-03 | 2018-08-09 | Celgene Corporation | Methods for measuring small molecule affinity to cereblon |
| CA3073125A1 (en) * | 2017-08-18 | 2019-02-21 | Cambridge Enterprise Limited | Modular binding proteins |
| EP3864030A4 (en) * | 2018-10-12 | 2022-09-21 | The Scripps Research Institute | Compounds and methods for dcaf-mediated protein degradation |
-
2021
- 2021-05-28 WO PCT/CN2021/096782 patent/WO2021239117A1/en not_active Ceased
- 2021-05-28 JP JP2022573579A patent/JP7898388B2/ja active Active
- 2021-05-28 EP EP21812627.4A patent/EP4157888A4/en active Pending
- 2021-05-28 CN CN202180058377.0A patent/CN116472292A/zh active Pending
- 2021-10-07 US US17/496,628 patent/US20230057177A1/en not_active Abandoned
-
2023
- 2023-07-28 US US18/361,422 patent/US20240066136A1/en active Pending