JP2023528280A5 - - Google Patents

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Publication number
JP2023528280A5
JP2023528280A5 JP2022570530A JP2022570530A JP2023528280A5 JP 2023528280 A5 JP2023528280 A5 JP 2023528280A5 JP 2022570530 A JP2022570530 A JP 2022570530A JP 2022570530 A JP2022570530 A JP 2022570530A JP 2023528280 A5 JP2023528280 A5 JP 2023528280A5
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JP
Japan
Prior art keywords
methyl
pyrazole
imidazole
dihydro
ethyl
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Granted
Application number
JP2022570530A
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English (en)
Japanese (ja)
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JP7734152B2 (ja
JP2023528280A (ja
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Priority claimed from JP2020090110A external-priority patent/JP2021183586A/ja
Application filed filed Critical
Publication of JP2023528280A publication Critical patent/JP2023528280A/ja
Publication of JP2023528280A5 publication Critical patent/JP2023528280A5/ja
Priority to JP2025139598A priority Critical patent/JP2025168429A/ja
Application granted granted Critical
Publication of JP7734152B2 publication Critical patent/JP7734152B2/ja
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JP2022570530A 2020-05-22 2021-05-20 例えば、うつ病を治療するための、gpr139拮抗薬としての1-((1h-ピラゾール-4-イル)メチル)-3-(フェニル)-1,3-ジヒドロ-2h-イミダゾール-2-オン誘導体および関連化合物 Active JP7734152B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025139598A JP2025168429A (ja) 2020-05-22 2025-08-25 例えば、うつ病を治療するための、gpr139拮抗薬としての1-((1h-ピラゾール-4-イル)メチル)-3-(フェニル)-1,3-ジヒドロ-2h-イミダゾール-2-オン誘導体および関連化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020090110 2020-05-22
JP2020090110A JP2021183586A (ja) 2020-05-22 2020-05-22 複素環化合物
PCT/IB2021/000336 WO2021234450A1 (en) 2020-05-22 2021-05-20 1-((1h-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2h-imidazol-2-one derivatives and related compounds as gpr139 antagonists for the treatment of e.g. depression

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025139598A Division JP2025168429A (ja) 2020-05-22 2025-08-25 例えば、うつ病を治療するための、gpr139拮抗薬としての1-((1h-ピラゾール-4-イル)メチル)-3-(フェニル)-1,3-ジヒドロ-2h-イミダゾール-2-オン誘導体および関連化合物

Publications (3)

Publication Number Publication Date
JP2023528280A JP2023528280A (ja) 2023-07-04
JP2023528280A5 true JP2023528280A5 (https=) 2024-05-23
JP7734152B2 JP7734152B2 (ja) 2025-09-04

Family

ID=76797025

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020090110A Pending JP2021183586A (ja) 2020-05-22 2020-05-22 複素環化合物
JP2022570530A Active JP7734152B2 (ja) 2020-05-22 2021-05-20 例えば、うつ病を治療するための、gpr139拮抗薬としての1-((1h-ピラゾール-4-イル)メチル)-3-(フェニル)-1,3-ジヒドロ-2h-イミダゾール-2-オン誘導体および関連化合物
JP2025139598A Pending JP2025168429A (ja) 2020-05-22 2025-08-25 例えば、うつ病を治療するための、gpr139拮抗薬としての1-((1h-ピラゾール-4-イル)メチル)-3-(フェニル)-1,3-ジヒドロ-2h-イミダゾール-2-オン誘導体および関連化合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020090110A Pending JP2021183586A (ja) 2020-05-22 2020-05-22 複素環化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025139598A Pending JP2025168429A (ja) 2020-05-22 2025-08-25 例えば、うつ病を治療するための、gpr139拮抗薬としての1-((1h-ピラゾール-4-イル)メチル)-3-(フェニル)-1,3-ジヒドロ-2h-イミダゾール-2-オン誘導体および関連化合物

Country Status (7)

Country Link
US (1) US20230348435A1 (https=)
EP (1) EP4153583B1 (https=)
JP (3) JP2021183586A (https=)
AR (1) AR122142A1 (https=)
ES (1) ES3001126T3 (https=)
TW (1) TW202208349A (https=)
WO (1) WO2021234450A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021183587A (ja) 2020-05-22 2021-12-02 武田薬品工業株式会社 複素環化合物
TW202400588A (zh) * 2022-02-28 2024-01-01 香港商維泰瑞隆(香港)生物科技有限公司 Rip1調製劑、其製備及用途
CN121159462A (zh) * 2025-11-19 2025-12-19 杭州市第七人民医院(杭州市心理危机研究与干预中心) 喹唑啉酮类化合物及其在制备神经系统疾病药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2374610A1 (en) 1999-06-28 2001-01-04 Jordan J. N. Tang Catalytically active recombinant memapsin and methods of use thereof
AR052342A1 (es) * 2004-12-21 2007-03-14 Janssen Pharmaceutica Nv Derivados sustituidos de triazolona,tetrazolona e imidazolona con actividad selectiva antagonista de alfa2c-adenoreceptores
US8148367B2 (en) 2007-01-12 2012-04-03 Takeda Pharmaceutical Company Limited Renin inhibitors
WO2008094556A2 (en) 2007-01-30 2008-08-07 Biogen Idec Ma Inc. Imidazolone compounds as tgf-beta family type i receptors, alk5 and/or alk4 antagonists
WO2011145735A1 (ja) * 2010-05-21 2011-11-24 武田薬品工業株式会社 チアゾール誘導体
AR103990A1 (es) * 2015-01-09 2017-06-21 Bristol Myers Squibb Co Ureas cíclicas como inhibidoras de rock
WO2020097609A1 (en) * 2018-11-09 2020-05-14 Blackthorn Therapeutics, Inc. Gpr139 receptor modulators
JP7199940B2 (ja) 2018-12-03 2023-01-06 川崎重工業株式会社 複合材料製航空機用部品およびその製造方法

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