JP2023527961A5 - - Google Patents
Info
- Publication number
- JP2023527961A5 JP2023527961A5 JP2022566301A JP2022566301A JP2023527961A5 JP 2023527961 A5 JP2023527961 A5 JP 2023527961A5 JP 2022566301 A JP2022566301 A JP 2022566301A JP 2022566301 A JP2022566301 A JP 2022566301A JP 2023527961 A5 JP2023527961 A5 JP 2023527961A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- compound
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063018371P | 2020-04-30 | 2020-04-30 | |
| US63/018,371 | 2020-04-30 | ||
| PCT/US2021/030335 WO2021222858A1 (en) | 2020-04-30 | 2021-04-30 | Antagonists of gpr39 protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023527961A JP2023527961A (ja) | 2023-07-03 |
| JP2023527961A5 true JP2023527961A5 (https=) | 2024-04-01 |
Family
ID=76035152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022566301A Pending JP2023527961A (ja) | 2020-04-30 | 2021-04-30 | ｇｐｒ３９タンパク質のアンタゴニスト |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230174484A1 (https=) |
| EP (1) | EP4143163A1 (https=) |
| JP (1) | JP2023527961A (https=) |
| KR (1) | KR20230017787A (https=) |
| CN (1) | CN115996908B (https=) |
| WO (1) | WO2021222858A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4267580A1 (en) * | 2020-12-22 | 2023-11-01 | Pathios Therapeutics Limited | N-(pyridin-2-yl)-6,7,8,9-tetrahydro-5h-5,8-epiminocyclohepta[c]pyridine-10-carboxamide derivatives and similar compounds as gpr65 modulators for the treatment of cancer |
| EP4486722A4 (en) * | 2022-03-02 | 2026-03-25 | Nico Therapeutics Inc | COMPOUNDS, COMPOSITIONS AND PROCESSES |
| CN117224684A (zh) * | 2023-09-27 | 2023-12-15 | 南京医科大学姑苏学院 | Gpr39抑制剂在制备预防或治疗高血压疾病的药物中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL91418A (en) * | 1988-09-01 | 1997-11-20 | Rhone Poulenc Agrochimie | (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them |
| DE10164564B4 (de) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
| US20040071708A1 (en) | 2002-09-26 | 2004-04-15 | Immusol, Inc. | GPR 39 modulators that control cancerous cell growth |
| WO2004099782A2 (en) * | 2003-05-05 | 2004-11-18 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor gpr39 (gpr39) |
| US7459460B2 (en) * | 2003-05-28 | 2008-12-02 | Bristol-Myers Squibb Company | Trisubstituted heteroaromatic compounds as calcium sensing receptor modulators |
| US7767680B2 (en) * | 2004-11-03 | 2010-08-03 | Vertex Pharmaceuticals Incorporated | Ion channel modulators and methods of use |
| CN1850269A (zh) | 2005-04-22 | 2006-10-25 | 中国科学院上海生命科学研究院 | Gpr39基因在哺乳动物中枢神经系统的功能及其应用 |
| MX2008015670A (es) | 2006-06-08 | 2009-01-12 | Janssen Pharmaceutica Nv | Receptor 39 acoplado a proteina g (gpr39). |
| CN106103421B (zh) * | 2014-02-14 | 2019-04-09 | 武田药品工业株式会社 | Gpr6的吡嗪调节剂 |
| KR20190097074A (ko) * | 2016-12-27 | 2019-08-20 | 다이이찌 산쿄 가부시키가이샤 | 피리미딘 유도체 |
-
2021
- 2021-04-30 WO PCT/US2021/030335 patent/WO2021222858A1/en not_active Ceased
- 2021-04-30 CN CN202180046666.9A patent/CN115996908B/zh active Active
- 2021-04-30 KR KR1020227041846A patent/KR20230017787A/ko active Pending
- 2021-04-30 EP EP21727055.2A patent/EP4143163A1/en active Pending
- 2021-04-30 JP JP2022566301A patent/JP2023527961A/ja active Pending
- 2021-04-30 US US17/997,533 patent/US20230174484A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023527961A5 (https=) | ||
| KR102800132B1 (ko) | Sting 작동 화합물 | |
| CN106687450B (zh) | 一种吲哚胺-2,3-双加氧酶抑制剂及其制备方法 | |
| CN101885722B (zh) | 杂环炔苯类化合物及其药用组合物和应用 | |
| JP5865519B2 (ja) | イミダゾピロリジノン化合物 | |
| JP2021523221A5 (https=) | ||
| KR102008635B1 (ko) | 영상화제의 합성 및 사용을 위한 조성물, 방법 및 시스템 | |
| CN105646389B (zh) | 一种作为吲哚胺-2,3-双加氧酶抑制剂的氨基磺酸脂及其制备方法和用途 | |
| CN103012399B (zh) | 7-氧代吡啶并嘧啶类化合物及其药用组合物和应用 | |
| JP2019517487A5 (https=) | ||
| RU2015118647A (ru) | Аминопиримидиновые соединения в качестве ингибиторов содержащих т790м мутантных egfr | |
| JP2007511504A5 (https=) | ||
| KR20160115991A (ko) | Midh1 억제제로서의 벤즈이미다졸-2-아민 | |
| RU2010154172A (ru) | Соединения для лечения рака | |
| JP2018536648A5 (https=) | ||
| JP2011524422A5 (https=) | ||
| JP2016526540A5 (https=) | ||
| JP2017533968A5 (https=) | ||
| WO2016082713A1 (zh) | 2-氨基嘧啶类化合物及其药物组合物和应用 | |
| JP2021509678A5 (https=) | ||
| JP2022119852A5 (https=) | ||
| JP2020504186A5 (https=) | ||
| EP2714703A1 (en) | Tricyclic inhibitors of poly(adp-ribose)polymerase | |
| CN101747330A (zh) | 吡啶基噻唑胺类化合物及其药用组合物和应用 | |
| JP2021514399A5 (https=) |