CN115996908B - Gpr39蛋白的拮抗剂 - Google Patents

Gpr39蛋白的拮抗剂

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Publication number
CN115996908B
CN115996908B CN202180046666.9A CN202180046666A CN115996908B CN 115996908 B CN115996908 B CN 115996908B CN 202180046666 A CN202180046666 A CN 202180046666A CN 115996908 B CN115996908 B CN 115996908B
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compound
alkyl
phenyl
pharmaceutically acceptable
acceptable salt
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CN115996908A (zh
Inventor
S·考尔
N·埃尔凯德
S·那伽拉詹
A·希安丘利
F·米切利
T·塞梅拉罗
I·M·L·特里斯特
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Oregon Health and Science University
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Oregon Health and Science University
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    • C07D209/54—Spiro-condensed
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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