JP2022119852A5 - - Google Patents

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Publication number
JP2022119852A5
JP2022119852A5 JP2022081736A JP2022081736A JP2022119852A5 JP 2022119852 A5 JP2022119852 A5 JP 2022119852A5 JP 2022081736 A JP2022081736 A JP 2022081736A JP 2022081736 A JP2022081736 A JP 2022081736A JP 2022119852 A5 JP2022119852 A5 JP 2022119852A5
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JP
Japan
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alkyl
pharmaceutically acceptable
tautomer
stereoisomer
geometric isomer
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JP2022081736A
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English (en)
Japanese (ja)
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JP2022119852A (ja
JP7384535B2 (ja
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Priority claimed from CN201611204309.8A external-priority patent/CN108239074B/zh
Priority claimed from CN201611211589.5A external-priority patent/CN108239075B/zh
Priority claimed from CN201611214102.9A external-priority patent/CN108239076B/zh
Priority claimed from JP2019534817A external-priority patent/JP7077323B2/ja
Application filed filed Critical
Publication of JP2022119852A publication Critical patent/JP2022119852A/ja
Publication of JP2022119852A5 publication Critical patent/JP2022119852A5/ja
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Publication of JP7384535B2 publication Critical patent/JP7384535B2/ja
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JP2022081736A 2016-12-26 2022-05-18 キナゾリン化合物並びにその調製方法、使用及び医薬組成物 Active JP7384535B2 (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CN201611204309.8A CN108239074B (zh) 2016-12-26 2016-12-26 喹唑啉类化合物及其制备方法、用途和药物组合物
CN201611214102.9 2016-12-26
CN201611211589.5A CN108239075B (zh) 2016-12-26 2016-12-26 喹唑啉类化合物及其制备方法、用途和药物组合物
CN201611204309.8 2016-12-26
CN201611211589.5 2016-12-26
CN201611214102.9A CN108239076B (zh) 2016-12-26 2016-12-26 喹唑啉类化合物及其制备方法、用途和药物组合物
JP2019534817A JP7077323B2 (ja) 2016-12-26 2017-12-26 キナゾリン化合物並びにその調製方法、使用及び医薬組成物
PCT/CN2017/118771 WO2018121550A1 (zh) 2016-12-26 2017-12-26 喹唑啉类化合物及其制备方法、用途和药物组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019534817A Division JP7077323B2 (ja) 2016-12-26 2017-12-26 キナゾリン化合物並びにその調製方法、使用及び医薬組成物

Publications (3)

Publication Number Publication Date
JP2022119852A JP2022119852A (ja) 2022-08-17
JP2022119852A5 true JP2022119852A5 (https=) 2022-11-09
JP7384535B2 JP7384535B2 (ja) 2023-11-21

Family

ID=62707834

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019534817A Active JP7077323B2 (ja) 2016-12-26 2017-12-26 キナゾリン化合物並びにその調製方法、使用及び医薬組成物
JP2022081738A Active JP7384536B2 (ja) 2016-12-26 2022-05-18 キナゾリン化合物並びにその調製方法、使用及び医薬組成物
JP2022081736A Active JP7384535B2 (ja) 2016-12-26 2022-05-18 キナゾリン化合物並びにその調製方法、使用及び医薬組成物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2019534817A Active JP7077323B2 (ja) 2016-12-26 2017-12-26 キナゾリン化合物並びにその調製方法、使用及び医薬組成物
JP2022081738A Active JP7384536B2 (ja) 2016-12-26 2022-05-18 キナゾリン化合物並びにその調製方法、使用及び医薬組成物

Country Status (7)

Country Link
US (3) US11534443B2 (https=)
EP (3) EP4169917B1 (https=)
JP (3) JP7077323B2 (https=)
CN (1) CN110382490A (https=)
AU (3) AU2017389818B2 (https=)
CA (3) CA3174865A1 (https=)
WO (1) WO2018121550A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11534443B2 (en) * 2016-12-26 2022-12-27 Institute Of Materia Medica, Chinese Academy Of Medical Sciences Quinazoline compounds, preparation method, use, and pharmaceutical composition thereof
WO2021088787A1 (zh) * 2019-11-07 2021-05-14 南京正大天晴制药有限公司 作为axl抑制剂的喹唑啉类化合物
CN113620976B (zh) * 2020-05-09 2023-09-26 中国医学科学院药物研究所 噻唑并嘧啶类化合物及其制备方法、用途和药物组合物
MX2023005747A (es) 2020-11-18 2023-07-28 Deciphera Pharmaceuticals Llc Inhibidores de gcn2 y perk quinasas y metodos de uso de los mismos.
KR20240113496A (ko) 2021-12-03 2024-07-22 데시페라 파마슈티칼스, 엘엘씨. Gcn2 및 perk 키나아제 억제제로서의 헤테로고리 화합물
CN119630431A (zh) * 2022-08-26 2025-03-14 卫材R&D管理有限公司 抗体药物缀合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960008781B1 (ko) * 1993-08-05 1996-07-03 김하운 연소효율 증강장치
ES2788383T3 (es) 2000-04-25 2020-10-21 Icos Corp Inhibidores de delta fosfatidilo-inositol 3-quinasa humana
PE20090288A1 (es) 2007-05-10 2009-04-03 Smithkline Beecham Corp Derivados de quinoxalina como inhibidores de la pi3 quinasa
PE20090717A1 (es) 2007-05-18 2009-07-18 Smithkline Beecham Corp Derivados de quinolina como inhibidores de la pi3 quinasa
UY31137A1 (es) 2007-06-14 2009-01-05 Smithkline Beecham Corp Derivados de quinazolina como inhibidores de la pi3 quinasa
US20100311736A1 (en) 2007-10-22 2010-12-09 Glaxosmithkline Llc Pyridosulfonamide derivatives as p13 kinase inhibitors
EP2984088B1 (en) * 2013-04-12 2019-03-20 Asana BioSciences, LLC Quinazolines and azaquinazolines as dual inhibitors of ras/raf/mek/erk and pi3k/akt/pten/mtor pathways
US11534443B2 (en) * 2016-12-26 2022-12-27 Institute Of Materia Medica, Chinese Academy Of Medical Sciences Quinazoline compounds, preparation method, use, and pharmaceutical composition thereof
CN108239074B (zh) 2016-12-26 2021-07-06 中国医学科学院药物研究所 喹唑啉类化合物及其制备方法、用途和药物组合物
CN108239075B (zh) 2016-12-26 2021-07-02 中国医学科学院药物研究所 喹唑啉类化合物及其制备方法、用途和药物组合物
CN108239076B (zh) 2016-12-26 2021-07-06 中国医学科学院药物研究所 喹唑啉类化合物及其制备方法、用途和药物组合物

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