JP2023526450A5 - - Google Patents
Info
- Publication number
- JP2023526450A5 JP2023526450A5 JP2022570570A JP2022570570A JP2023526450A5 JP 2023526450 A5 JP2023526450 A5 JP 2023526450A5 JP 2022570570 A JP2022570570 A JP 2022570570A JP 2022570570 A JP2022570570 A JP 2022570570A JP 2023526450 A5 JP2023526450 A5 JP 2023526450A5
- Authority
- JP
- Japan
- Prior art keywords
- conjugate
- antibody
- fusion protein
- glycosylated
- ionic strength
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025230733A JP2026052060A (ja) | 2020-05-20 | 2025-12-04 | グリコシル化Ｆｃドメインを含むタンパク質の部位特異的コンジュゲーションのための方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063027400P | 2020-05-20 | 2020-05-20 | |
| US63/027,400 | 2020-05-20 | ||
| PCT/IB2021/054310 WO2021234593A1 (en) | 2020-05-20 | 2021-05-19 | Methods for site specific conjugation of proteins containing glycosylated fc domains |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025230733A Division JP2026052060A (ja) | 2020-05-20 | 2025-12-04 | グリコシル化Ｆｃドメインを含むタンパク質の部位特異的コンジュゲーションのための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023526450A JP2023526450A (ja) | 2023-06-21 |
| JP2023526450A5 true JP2023526450A5 (https=) | 2024-05-24 |
| JP7787101B2 JP7787101B2 (ja) | 2025-12-16 |
Family
ID=76355544
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022570570A Active JP7787101B2 (ja) | 2020-05-20 | 2021-05-19 | グリコシル化Ｆｃドメインを含むタンパク質の部位特異的コンジュゲーションのための方法 |
| JP2025230733A Pending JP2026052060A (ja) | 2020-05-20 | 2025-12-04 | グリコシル化Ｆｃドメインを含むタンパク質の部位特異的コンジュゲーションのための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025230733A Pending JP2026052060A (ja) | 2020-05-20 | 2025-12-04 | グリコシル化Ｆｃドメインを含むタンパク質の部位特異的コンジュゲーションのための方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12084475B2 (https=) |
| EP (1) | EP4153632A1 (https=) |
| JP (2) | JP7787101B2 (https=) |
| KR (1) | KR20230011417A (https=) |
| CN (1) | CN115916832A (https=) |
| AU (1) | AU2021276653A1 (https=) |
| BR (1) | BR112022023557A2 (https=) |
| CA (1) | CA3183906A1 (https=) |
| IL (1) | IL298344A (https=) |
| MX (1) | MX2022014530A (https=) |
| WO (1) | WO2021234593A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026052110A1 (en) * | 2024-09-09 | 2026-03-12 | Genequantum Healthcare (Suzhou) Co., Ltd. | Enzyme-catalyzed site-specific antibody-oligonucleotide conjugates (aocs) conjugation method |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10434197B2 (en) | 2010-07-23 | 2019-10-08 | University Of Delaware | Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes |
| US10556024B2 (en) | 2013-11-13 | 2020-02-11 | Whitehead Institute For Biomedical Research | 18F labeling of proteins using sortases |
| WO2015191883A1 (en) * | 2014-06-12 | 2015-12-17 | Dophen Biomedical | Homogenous antibody drug conjugates via enzymatic methods |
| PL3185908T3 (pl) * | 2014-08-28 | 2020-09-07 | Pfizer Inc. | Łączniki modulujące stabilność do stosowania z koniugatami przeciwciało-lek |
| JP2018531935A (ja) * | 2015-10-02 | 2018-11-01 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | 抗体を結合させるためのトランスグルタミナーゼバリアント |
| EA201891723A1 (ru) * | 2016-02-05 | 2018-12-28 | Милленниум Фармасьютикалз, Инк. | Gcc-направленные конъюгаты антитело-лекарство |
| MY202858A (en) | 2016-06-10 | 2024-05-25 | Eisai R&D Man Co Ltd | Lysine conjugated immunoglobulins |
| WO2018218004A1 (en) * | 2017-05-24 | 2018-11-29 | The Board Of Regents Of The University Of Texas System | Linkers for antibody drug conjugates |
| NZ762376A (en) * | 2017-09-19 | 2022-08-26 | Scherrer Inst Paul | Transglutaminase conjugation method and linker |
| MX2020004381A (es) * | 2017-10-27 | 2020-08-20 | Pfizer | Anticuerpos y conjugados de anticuerpo-farmaco especificos para cd123 y usos de los mismos. |
| BR112020012099A2 (pt) | 2017-12-18 | 2020-11-17 | Janssen Biotech, Inc. | radiomarcação de polipeptídeos |
| PE20211916A1 (es) | 2018-05-24 | 2021-09-28 | Janssen Biotech Inc | Agentes aglutinantes del psma y usos de estos |
-
2021
- 2021-05-19 JP JP2022570570A patent/JP7787101B2/ja active Active
- 2021-05-19 AU AU2021276653A patent/AU2021276653A1/en active Pending
- 2021-05-19 CA CA3183906A patent/CA3183906A1/en active Pending
- 2021-05-19 WO PCT/IB2021/054310 patent/WO2021234593A1/en not_active Ceased
- 2021-05-19 EP EP21731295.8A patent/EP4153632A1/en active Pending
- 2021-05-19 US US17/324,150 patent/US12084475B2/en active Active
- 2021-05-19 CN CN202180036145.5A patent/CN115916832A/zh active Pending
- 2021-05-19 KR KR1020227044511A patent/KR20230011417A/ko active Pending
- 2021-05-19 MX MX2022014530A patent/MX2022014530A/es unknown
- 2021-05-19 BR BR112022023557A patent/BR112022023557A2/pt unknown
- 2021-05-19 IL IL298344A patent/IL298344A/en unknown
-
2024
- 2024-08-02 US US18/792,966 patent/US20240384002A1/en active Pending
-
2025
- 2025-12-04 JP JP2025230733A patent/JP2026052060A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2020022363A5 (https=) | ||
| CA1341124C (en) | Genetic engineering process for the preparation of hirudins, and means for carrying out this process | |
| US7193041B2 (en) | Method for purification of recombinant proteins | |
| JP6357154B2 (ja) | 荷電性非タンパク質性アミノ酸含有ペプチドの製造方法 | |
| JPH06500006A (ja) | ユビキチン特異的プロテアーゼ | |
| JP2008521415A (ja) | カルボキシ末端をアミド化したペプチドの製造方法 | |
| JP2023526450A5 (https=) | ||
| JPS61158793A (ja) | ヒト・リゾチ−ムの合成遺伝子 | |
| WO2002090537A1 (en) | Process for synthesizing protein using cell-free protein synthesis system | |
| JPH044872A (ja) | 細胞質外酵素と少なくとも１つの他のタンパク質とのハイブリッドタンパク質およびその製造方法 | |
| CZ20011523A3 (cs) | Enzymatická amidace peptidů | |
| WO2003060073A3 (en) | An in vivo protein screen based on enzyme-assisted chemically induced dimerization ('cid') | |
| EP0085516B1 (en) | A process for enzymatic replacement of the b-30 amino acid in insulins | |
| WO2003062417A1 (fr) | Produit de ligation arn-adn, et utilisation correspondante | |
| Wang et al. | The diversity of glycosylation of cellobiohydrolase I from Trichoderma reesei determined with mass spectrometry | |
| US6841658B2 (en) | Purification of human Troponin I | |
| Hønberg | Probing barley mutants with a monoclonal antibody to a polypeptide involved in photosynthetic oxygen evolution | |
| JP2887063B2 (ja) | グリセンチンの製造方法 | |
| EP1133566B1 (en) | Dna encoding fusion proteins which are specifically cleavable by copper (ii) ions | |
| WO2025011561A1 (en) | Antibody-drug conjugates and production thereof | |
| EP4709852A1 (en) | New high expression and high activity n-glycosidases, methods of production and applications thereof | |
| CN103275999B (zh) | 一种绿盲蝽膜结合型海藻糖酶、其编码序列、载体、菌株及应用 | |
| JPH0242990A (ja) | 組換え融合タンパク質および組換えベクター | |
| SU1597391A1 (ru) | Способ получени лейциновой т-РНК | |
| WO2023062397A1 (en) | Tagged exoglycosidase enzymes and immobilized glycan sequencing approach |