JP2023526421A5 - - Google Patents

Info

Publication number
JP2023526421A5
JP2023526421A5 JP2022570510A JP2022570510A JP2023526421A5 JP 2023526421 A5 JP2023526421 A5 JP 2023526421A5 JP 2022570510 A JP2022570510 A JP 2022570510A JP 2022570510 A JP2022570510 A JP 2022570510A JP 2023526421 A5 JP2023526421 A5 JP 2023526421A5
Authority
JP
Japan
Prior art keywords
hsigg
reaction mixture
enzymatically active
bis
branching
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022570510A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023526421A (ja
JP7835691B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/033150 external-priority patent/WO2021236765A1/en
Publication of JP2023526421A publication Critical patent/JP2023526421A/ja
Publication of JP2023526421A5 publication Critical patent/JP2023526421A5/ja
Application granted granted Critical
Publication of JP7835691B2 publication Critical patent/JP7835691B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022570510A 2020-05-19 2021-05-19 高シアル化免疫グロブリン Active JP7835691B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063026826P 2020-05-19 2020-05-19
US63/026,826 2020-05-19
US202063108741P 2020-11-02 2020-11-02
US63/108,741 2020-11-02
PCT/US2021/033150 WO2021236765A1 (en) 2020-05-19 2021-05-19 Hyper-sialylated immunoglobulin

Publications (3)

Publication Number Publication Date
JP2023526421A JP2023526421A (ja) 2023-06-21
JP2023526421A5 true JP2023526421A5 (https=) 2025-04-11
JP7835691B2 JP7835691B2 (ja) 2026-03-25

Family

ID=78708031

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022570510A Active JP7835691B2 (ja) 2020-05-19 2021-05-19 高シアル化免疫グロブリン

Country Status (11)

Country Link
US (1) US20230192814A1 (https=)
EP (1) EP4153622A4 (https=)
JP (1) JP7835691B2 (https=)
KR (1) KR20230012576A (https=)
CN (1) CN115867571A (https=)
AU (1) AU2021275115A1 (https=)
BR (1) BR112022023334A2 (https=)
CA (1) CA3182136A1 (https=)
CO (1) CO2022016670A2 (https=)
MX (1) MX2022014525A (https=)
WO (1) WO2021236765A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2877589B1 (en) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glycoproteins with anti-inflammatory properties
WO2014186310A1 (en) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
CA3174533A1 (en) * 2020-03-05 2021-09-10 Momenta Pharmaceuticals, Inc. Methods of making hyper-sialylated immunoglobulin
WO2026014960A1 (ko) * 2024-07-11 2026-01-15 건국대학교 산학협력단 인간으로부터 분리한 형질세포들을 이용한 α-2,6-시알산화 면역글로불린의 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101613705A (zh) * 2002-03-19 2009-12-30 国际植物研究所 在植物中优化聚糖生成
ES2805964T3 (es) * 2008-10-29 2021-02-16 Janssen Biotech Inc Composiciones de galactosa alfa (1-3) galactosa
ES2802274T3 (es) 2013-05-02 2021-01-18 Momenta Pharmaceuticals Inc Glicoproteínas sialiladas
EP2821482A1 (en) * 2013-07-05 2015-01-07 Roche Diagniostics GmbH N-terminally truncated glycosyltransferases
JP6931058B2 (ja) * 2016-12-21 2021-09-01 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 抗体のインビトロ糖鎖工学における酵素の再使用
US20210353752A1 (en) * 2018-10-11 2021-11-18 Momenta Pharmaceuticals, Inc. Treatment with highly silylated igg compositions
JP7398002B2 (ja) 2020-02-14 2023-12-13 北京小米移動軟件有限公司 フィードバック方式の指示及び決定方法、装置、記憶媒体
KR20230012560A (ko) 2020-05-19 2023-01-26 모멘타 파머슈티컬스 인코포레이티드 과시알화된 IgG의 제조 및 정제
JP2023538400A (ja) * 2020-08-21 2023-09-07 モメンタ ファーマシューティカルズ インコーポレイテッド 高シアル化免疫グロブリン

Similar Documents

Publication Publication Date Title
JP2023526421A5 (https=)
Gilbert et al. The synthesis of sialylated oligosaccharides using a CMP-Neu5Ac synthetase/sialyltransferase fusion
JP3158106B2 (ja) モノクローナル抗体及びその製造法
US9987373B2 (en) Modified glycoprotein, protein-conjugate and process for the preparation thereof
Lin et al. Sequential glycosylation of proteins with substrate-specific N-glycosyltransferases
TW201602353A (zh) 寡醣之大規模酵素合成
Renkonen et al. Synthesis of a new nanomolar saccharide inhibitor of lymphocyte adhesion: different polylactosamine backbones present multiple sialyl Lewis x determinants to L-selectin in high-affinity mode
JP2023509476A5 (https=)
RU2010101024A (ru) Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях
TW201247873A (en) Method for producing sialic-acid-containing sugar chain
US5156965A (en) Catalytic antibodies
JP7835691B2 (ja) 高シアル化免疫グロブリン
Yamamoto Recent advances in glycotechnology for glycoconjugate synthesis using microbial endoglycosidases
JP5687271B2 (ja) 酵素による抗体処理方法
WO2019196697A1 (zh) 一种降低抗体核心岩藻糖基化的方法和组合物
JP6718561B2 (ja) 活性型ＧｃＭＡＦの製造方法
CA3173252A1 (en) Enzymes for sialylation of glycans
CN103146773A (zh) 一种增强大肠杆菌l-苯丙氨酸胞外分泌的方法
JP2021145548A (ja) ＥＮＧａｓｅまたはその変異体を用いた４本鎖糖鎖を有するＩｇＧ抗体の調製方法
US9365881B2 (en) Process for antibody G1 glycoform production
EP4458961A1 (en) Isolated polypeptide and use thereof
CA3062238A1 (en) Glycosylation of variable immunoglobulin domains
JP2023526527A5 (https=)
WO2006043305A1 (ja) 糖転移酵素の酵素活性を向上させる方法
KR20200100588A (ko) 재조합 폴리펩티드에서의 조작된 o-당화 및 이의 용도