JP2023526234A5 - - Google Patents

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Publication number
JP2023526234A5
JP2023526234A5 JP2022568746A JP2022568746A JP2023526234A5 JP 2023526234 A5 JP2023526234 A5 JP 2023526234A5 JP 2022568746 A JP2022568746 A JP 2022568746A JP 2022568746 A JP2022568746 A JP 2022568746A JP 2023526234 A5 JP2023526234 A5 JP 2023526234A5
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JP
Japan
Prior art keywords
approximately
spacer
acid sequence
amino acid
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022568746A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023526234A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/032098 external-priority patent/WO2021231655A1/en
Publication of JP2023526234A publication Critical patent/JP2023526234A/ja
Publication of JP2023526234A5 publication Critical patent/JP2023526234A5/ja
Pending legal-status Critical Current

Links

JP2022568746A 2020-05-12 2021-05-12 キメラ抗原受容体スペーサー Pending JP2023526234A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063023751P 2020-05-12 2020-05-12
US63/023,751 2020-05-12
PCT/US2021/032098 WO2021231655A1 (en) 2020-05-12 2021-05-12 Chimeric antigen receptor spacers

Publications (2)

Publication Number Publication Date
JP2023526234A JP2023526234A (ja) 2023-06-21
JP2023526234A5 true JP2023526234A5 (enExample) 2024-07-31

Family

ID=76250478

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022568746A Pending JP2023526234A (ja) 2020-05-12 2021-05-12 キメラ抗原受容体スペーサー

Country Status (11)

Country Link
US (2) US20210380658A1 (enExample)
EP (1) EP4149968A1 (enExample)
JP (1) JP2023526234A (enExample)
KR (1) KR20230022411A (enExample)
CN (1) CN116096739A (enExample)
AU (1) AU2021270299A1 (enExample)
BR (1) BR112022022953A2 (enExample)
CA (2) CA3157427A1 (enExample)
IL (1) IL298114A (enExample)
MX (1) MX2022014203A (enExample)
WO (1) WO2021231655A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4121447A1 (en) 2020-03-20 2023-01-25 Lyell Immunopharma, Inc. Novel recombinant cell surface markers
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
US20250011399A1 (en) * 2021-11-10 2025-01-09 Outpace Bio, Inc. Chimeric antigen receptors
CN115724986B (zh) * 2022-07-11 2024-07-19 惠和生物技术(上海)有限公司 三特异性抗体及其用途

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
JP3614866B2 (ja) 1997-06-12 2005-01-26 リサーチ コーポレイション テクノロジーズ,インコーポレイティド 人工抗体ポリペプチド
CN1294148C (zh) 2001-04-11 2007-01-10 中国科学院遗传与发育生物学研究所 环状单链三特异抗体
CA2531118C (en) 2003-07-01 2013-01-08 Immunomedics, Inc. Multivalent carriers of bi-specific antibodies
EP1786918A4 (en) 2004-07-17 2009-02-11 Imclone Systems Inc NEW BISPECIFIC ANTIBODY TETRAVALENT
KR20140053410A (ko) 2005-08-19 2014-05-07 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
US20100047171A1 (en) * 2006-01-24 2010-02-25 Roland Beckmann Fusion Proteins That Contain Natural Junctions
US9316646B2 (en) 2009-04-23 2016-04-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-human ROR1 antibodies
EP2646469B1 (en) 2010-12-01 2017-11-01 The United States of America, as represented by The Secretary, Department of Health and Human Services Chimeric rabbit/human ror1 antibodies
GB201203071D0 (en) * 2012-02-22 2012-04-04 Ucb Pharma Sa Biological products
LT2884999T (lt) * 2012-08-20 2021-04-12 Fred Hutchinson Cancer Research Center Ląstelinės imunoterapijos būdas ir kompozicijos
CN107074957B (zh) * 2014-01-13 2021-05-07 希望之城公司 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法
US10752684B2 (en) * 2014-07-29 2020-08-25 Cellectis ROR1 (NTRKR1) specific chimeric antigen receptors for cancer immunotherapy
US20160208018A1 (en) * 2015-01-16 2016-07-21 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for ror1
GB201803079D0 (en) * 2018-02-26 2018-04-11 Autolus Ltd Cell
JP7438123B2 (ja) * 2018-03-14 2024-02-26 シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) 腫瘍特異的T細胞免疫療法用のIL-13受容体α2(IL13Rα2)標的キメラ抗原受容体
EP3774866A1 (en) * 2018-04-13 2021-02-17 Ludwig Institute for Cancer Research Ltd Heterodimeric inactivatable chimeric antigen receptors
BR112020022185A2 (pt) * 2018-05-03 2021-02-02 Juno Therapeutics Inc terapia de combinação de uma terapia de células t do receptor de antígeno quimérico (car) e um inibidor de quinase
EP3807317A4 (en) * 2018-06-15 2022-03-30 The Regents of University of California CHIMERIC FUSION FRAGMENT ANTIGEN RECEPTORS AND USES THEREOF
WO2020167957A1 (en) * 2019-02-12 2020-08-20 Board Of Regents, The University Of Texas System High affinity engineered t-cell receptors targeting cmv infected cells
AU2020295715A1 (en) * 2019-06-19 2022-02-17 Julius-Maximilians-Universität Würzburg Ultramodular IgG3-based spacer domain and multi-function site for implementation in chimeric antigen receptor design

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