JP2023526156A5 - - Google Patents
Info
- Publication number
- JP2023526156A5 JP2023526156A5 JP2022556459A JP2022556459A JP2023526156A5 JP 2023526156 A5 JP2023526156 A5 JP 2023526156A5 JP 2022556459 A JP2022556459 A JP 2022556459A JP 2022556459 A JP2022556459 A JP 2022556459A JP 2023526156 A5 JP2023526156 A5 JP 2023526156A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- gene expression
- cells
- expression profile
- hla
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062992701P | 2020-03-20 | 2020-03-20 | |
| US62/992,701 | 2020-03-20 | ||
| PCT/US2021/023240 WO2021188954A1 (en) | 2020-03-20 | 2021-03-19 | Methods of isolating t-cells and t-cell receptors from tumor by single-cell analysis for immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023526156A JP2023526156A (ja) | 2023-06-21 |
| JP2023526156A5 true JP2023526156A5 (https=) | 2024-04-03 |
Family
ID=75498029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556459A Pending JP2023526156A (ja) | 2020-03-20 | 2021-03-19 | 免疫療法のためのｔ細胞及びｔ細胞受容体を単一細胞解析により腫瘍から単離する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230138309A1 (https=) |
| EP (1) | EP4121515A1 (https=) |
| JP (1) | JP2023526156A (https=) |
| KR (1) | KR20220157435A (https=) |
| CN (1) | CN115485370A (https=) |
| AU (1) | AU2021237717A1 (https=) |
| CA (1) | CA3171559A1 (https=) |
| IL (1) | IL296629A (https=) |
| WO (1) | WO2021188954A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220257656A1 (en) * | 2019-07-10 | 2022-08-18 | National Cancer Center | Specific marker for identifying t cells specifically attacking cancer cells |
| MX2023011151A (es) | 2021-03-23 | 2024-01-18 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Receptores de celulas t reactivas a antigenos. |
| WO2025032194A1 (en) * | 2023-08-08 | 2025-02-13 | Ospedale San Raffaele S.R.L. | T-cell receptors |
| EP4603599A1 (en) | 2024-02-13 | 2025-08-20 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Identification of reactive t cell receptors |
| EP4603598A1 (en) | 2024-02-13 | 2025-08-20 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Identification of reactive t cells |
| WO2025184104A1 (en) * | 2024-02-26 | 2025-09-04 | The Medical College Of Wisconsin, Inc. | Methods of detecting neoantigen-specific t cells and t cell receptor sequences |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8034334B2 (en) | 2002-09-06 | 2011-10-11 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy |
| US8383099B2 (en) | 2009-08-28 | 2013-02-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adoptive cell therapy with young T cells |
| US20120244133A1 (en) | 2011-03-22 | 2012-09-27 | The United States of America, as represented by the Secretary, Department of Health and | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| JP6599450B2 (ja) | 2014-10-02 | 2019-10-30 | アメリカ合衆国 | がん特異的突然変異に対し抗原特異性を有するｔ細胞を単離する方法 |
| AU2014407539B2 (en) | 2014-10-02 | 2020-10-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating T cell receptors having antigenic specificity for a cancer-specific mutation |
| EP3234130B1 (en) * | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| WO2016179006A1 (en) * | 2015-05-01 | 2016-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating t cells and t cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
| WO2017048614A1 (en) * | 2015-09-15 | 2017-03-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating tumor-reactive t cell receptors from tumor or peripheral blood |
| WO2017191274A2 (en) * | 2016-05-04 | 2017-11-09 | Curevac Ag | Rna encoding a therapeutic protein |
| JP2019532997A (ja) * | 2016-11-03 | 2019-11-14 | ジュノー セラピューティクス インコーポレイテッド | Ｔ細胞療法とｂｔｋ阻害剤との併用療法 |
| KR20190098747A (ko) * | 2016-12-05 | 2019-08-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 치료법을 위한 조작된 세포의 제조방법 |
| WO2018106972A1 (en) * | 2016-12-07 | 2018-06-14 | La Jolla Institute For Allergy And Immunology | Compositions for cancer treatment and methods and uses for cancer treatment and prognosis |
| CN110612446B (zh) | 2017-03-31 | 2023-07-04 | 美国卫生和人力服务部 | 分离新抗原-特异性t细胞受体序列的方法 |
| EP3622092A4 (en) * | 2017-05-11 | 2021-06-23 | The Broad Institute, Inc. | METHODS AND COMPOSITIONS OF USE OF CD8 + TUMOR-INFILTRATING LYMPHOCYTE SUBTYPES AND GENE SIGNATURES THEREOF |
| ES3000510T3 (en) * | 2017-06-09 | 2025-02-28 | Providence Health & Services Oregon | Tumor-infiltrating t-cells for use in the treatment of cancer |
| US20210263012A1 (en) * | 2017-11-17 | 2021-08-26 | The Broad Institute, Inc. | Methods and compositions for modulating immune responses and lymphocyte activity |
| US20220033774A1 (en) * | 2018-04-16 | 2022-02-03 | The Regents Of The University Of California | Compositions and methods for cytotoxic cd4+ t cells |
-
2021
- 2021-03-19 CA CA3171559A patent/CA3171559A1/en active Pending
- 2021-03-19 KR KR1020227036214A patent/KR20220157435A/ko active Pending
- 2021-03-19 EP EP21718712.9A patent/EP4121515A1/en active Pending
- 2021-03-19 AU AU2021237717A patent/AU2021237717A1/en active Pending
- 2021-03-19 WO PCT/US2021/023240 patent/WO2021188954A1/en not_active Ceased
- 2021-03-19 IL IL296629A patent/IL296629A/en unknown
- 2021-03-19 US US17/912,315 patent/US20230138309A1/en active Pending
- 2021-03-19 CN CN202180022592.5A patent/CN115485370A/zh active Pending
- 2021-03-19 JP JP2022556459A patent/JP2023526156A/ja active Pending
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