JP2023526157A5 - - Google Patents
Info
- Publication number
- JP2023526157A5 JP2023526157A5 JP2022556460A JP2022556460A JP2023526157A5 JP 2023526157 A5 JP2023526157 A5 JP 2023526157A5 JP 2022556460 A JP2022556460 A JP 2022556460A JP 2022556460 A JP2022556460 A JP 2022556460A JP 2023526157 A5 JP2023526157 A5 JP 2023526157A5
- Authority
- JP
- Japan
- Prior art keywords
- hla
- expression profile
- cells
- gene expression
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062992715P | 2020-03-20 | 2020-03-20 | |
| US62/992,715 | 2020-03-20 | ||
| PCT/US2021/023225 WO2021188941A1 (en) | 2020-03-20 | 2021-03-19 | Methods of isolating t cells and t-cell receptors from peripheral blood by single-cell analysis for immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023526157A JP2023526157A (ja) | 2023-06-21 |
| JP2023526157A5 true JP2023526157A5 (https=) | 2024-04-03 |
Family
ID=75478263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556460A Pending JP2023526157A (ja) | 2020-03-20 | 2021-03-19 | 単一細胞解析により末梢血からｔ細胞及びｔ細胞レセプターを免疫治療のために単離する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230183802A1 (https=) |
| EP (1) | EP4121513A1 (https=) |
| JP (1) | JP2023526157A (https=) |
| KR (1) | KR20220161361A (https=) |
| CN (1) | CN115485368A (https=) |
| AU (1) | AU2021239379A1 (https=) |
| CA (1) | CA3171583A1 (https=) |
| IL (1) | IL296608A (https=) |
| WO (1) | WO2021188941A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4594751A1 (en) | 2022-09-27 | 2025-08-06 | UCL Business Ltd | Detecting cancer |
| GB202302709D0 (en) * | 2023-02-24 | 2023-04-12 | Genome Res Ltd | Method of identifying t cell recpetors of interest |
| WO2024197072A2 (en) * | 2023-03-21 | 2024-09-26 | Alaunos Therapeutics, Inc. | Identification of neoantigen-reactive t cell receptors |
| EP4603598A1 (en) * | 2024-02-13 | 2025-08-20 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Identification of reactive t cells |
| CN121208363B (zh) * | 2025-11-26 | 2026-03-17 | 中国人民解放军总医院第一医学中心 | IgA肾病的致病T细胞亚群的鉴定用试剂盒及鉴定系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8034334B2 (en) | 2002-09-06 | 2011-10-11 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy |
| US8383099B2 (en) | 2009-08-28 | 2013-02-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adoptive cell therapy with young T cells |
| US20120244133A1 (en) | 2011-03-22 | 2012-09-27 | The United States of America, as represented by the Secretary, Department of Health and | Methods of growing tumor infiltrating lymphocytes in gas-permeable containers |
| EP3628322A1 (en) * | 2013-03-01 | 2020-04-01 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Cd8+ t cells that also express pd-1 and/or tim-3 for the treatment of cancer |
| JP6599450B2 (ja) | 2014-10-02 | 2019-10-30 | アメリカ合衆国 | がん特異的突然変異に対し抗原特異性を有するｔ細胞を単離する方法 |
| AU2014407539B2 (en) | 2014-10-02 | 2020-10-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating T cell receptors having antigenic specificity for a cancer-specific mutation |
| EP3234130B1 (en) * | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| WO2016179006A1 (en) * | 2015-05-01 | 2016-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating t cells and t cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
| WO2017048614A1 (en) | 2015-09-15 | 2017-03-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating tumor-reactive t cell receptors from tumor or peripheral blood |
| CN110612446B (zh) | 2017-03-31 | 2023-07-04 | 美国卫生和人力服务部 | 分离新抗原-特异性t细胞受体序列的方法 |
| US20210263012A1 (en) * | 2017-11-17 | 2021-08-26 | The Broad Institute, Inc. | Methods and compositions for modulating immune responses and lymphocyte activity |
| WO2019112932A1 (en) * | 2017-12-04 | 2019-06-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of enriching cell populations for cancer-specific t cells using in vitro stimulation of memory t cells |
| US20220033774A1 (en) * | 2018-04-16 | 2022-02-03 | The Regents Of The University Of California | Compositions and methods for cytotoxic cd4+ t cells |
-
2021
- 2021-03-19 AU AU2021239379A patent/AU2021239379A1/en active Pending
- 2021-03-19 CA CA3171583A patent/CA3171583A1/en active Pending
- 2021-03-19 EP EP21718376.3A patent/EP4121513A1/en active Pending
- 2021-03-19 KR KR1020227036226A patent/KR20220161361A/ko active Pending
- 2021-03-19 WO PCT/US2021/023225 patent/WO2021188941A1/en not_active Ceased
- 2021-03-19 JP JP2022556460A patent/JP2023526157A/ja active Pending
- 2021-03-19 US US17/906,524 patent/US20230183802A1/en active Pending
- 2021-03-19 IL IL296608A patent/IL296608A/en unknown
- 2021-03-19 CN CN202180030252.7A patent/CN115485368A/zh active Pending
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