JP2023524812A5 - - Google Patents

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Publication number
JP2023524812A5
JP2023524812A5 JP2022567560A JP2022567560A JP2023524812A5 JP 2023524812 A5 JP2023524812 A5 JP 2023524812A5 JP 2022567560 A JP2022567560 A JP 2022567560A JP 2022567560 A JP2022567560 A JP 2022567560A JP 2023524812 A5 JP2023524812 A5 JP 2023524812A5
Authority
JP
Japan
Prior art keywords
linker compound
alkyl
independently
present
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022567560A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023524812A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/031287 external-priority patent/WO2021226454A1/en
Publication of JP2023524812A publication Critical patent/JP2023524812A/ja
Publication of JP2023524812A5 publication Critical patent/JP2023524812A5/ja
Pending legal-status Critical Current

Links

JP2022567560A 2020-05-08 2021-05-07 リンカー化合物 Pending JP2023524812A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063022313P 2020-05-08 2020-05-08
US63/022,313 2020-05-08
PCT/US2021/031287 WO2021226454A1 (en) 2020-05-08 2021-05-07 Linker compounds

Publications (2)

Publication Number Publication Date
JP2023524812A JP2023524812A (ja) 2023-06-13
JP2023524812A5 true JP2023524812A5 (enExample) 2024-05-14

Family

ID=78468445

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567560A Pending JP2023524812A (ja) 2020-05-08 2021-05-07 リンカー化合物

Country Status (4)

Country Link
US (1) US20230201358A1 (enExample)
EP (1) EP4146280A4 (enExample)
JP (1) JP2023524812A (enExample)
WO (1) WO2021226454A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120475995A (zh) * 2022-08-17 2025-08-12 隆萨销售股份有限公司 包含生物活性分子和可裂解接头的细胞外囊泡
US20260055404A1 (en) * 2022-08-17 2026-02-26 Lonza Sales Ag Extracellular vesicle comprising a biologically active molecule and a cell penetrating peptide cleavable linker
WO2024040075A1 (en) * 2022-08-17 2024-02-22 Lonza Sales Ag Extracellular vesicle comprising a biologically active molecule and a dual cleavable linker
WO2025157273A1 (en) * 2024-01-25 2025-07-31 Shanghai Rona Therapeutics Co., Ltd. Two or more nucleic acid molecules connected by a linker

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916750A (en) * 1997-01-08 1999-06-29 Biogenex Laboratories Multifunctional linking reagents for synthesis of branched oligomers
AU2011343664B2 (en) * 2010-12-17 2015-10-08 Arrowhead Pharmaceuticals, Inc. Galactose cluster-pharmacokinetic modulator targeting moiety for siRNA
WO2013173337A2 (en) * 2012-05-15 2013-11-21 Seattle Genetics, Inc. Self-stabilizing linker conjugates
EP3077406B1 (en) * 2013-12-05 2019-07-10 New England Biolabs, Inc. Compositions and methods for capping rna
TWI614264B (zh) * 2015-05-20 2018-02-11 免疫功坊股份有限公司 含胜肽核的多臂接合物及其應用
IL280536B2 (en) * 2018-08-02 2024-12-01 Dyne Therapeutics Inc Complexes targeting transferrin receptor and uses thereof

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