JP2023524146A - 低酸素血症の治療に使用されるメチルチオニニウム化合物 - Google Patents

低酸素血症の治療に使用されるメチルチオニニウム化合物 Download PDF

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Publication number
JP2023524146A
JP2023524146A JP2022567338A JP2022567338A JP2023524146A JP 2023524146 A JP2023524146 A JP 2023524146A JP 2022567338 A JP2022567338 A JP 2022567338A JP 2022567338 A JP2022567338 A JP 2022567338A JP 2023524146 A JP2023524146 A JP 2023524146A
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Japan
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subject
acid
containing compound
daily dose
hypoxia
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JP2022567338A
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English (en)
Japanese (ja)
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JP2023524146A5 (https=
Inventor
ミシェル ウィスチク，クロード
アラスト，モハマド
フィリップ マザネッツ，マイケル
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ウィスタ ラボラトリーズ リミテッド
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Priority claimed from GBGB2006659.3A external-priority patent/GB202006659D0/en
Priority claimed from GBGB2016957.9A external-priority patent/GB202016957D0/en
Application filed by ウィスタ ラボラトリーズ リミテッド filed Critical ウィスタ ラボラトリーズ リミテッド
Publication of JP2023524146A publication Critical patent/JP2023524146A/ja
Publication of JP2023524146A5 publication Critical patent/JP2023524146A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022567338A 2020-05-05 2021-04-30 低酸素血症の治療に使用されるメチルチオニニウム化合物 Pending JP2023524146A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2006659.3 2020-05-05
GBGB2006659.3A GB202006659D0 (en) 2020-05-05 2020-05-05 Therapeutic treatments
GB2016957.9 2020-10-26
GBGB2016957.9A GB202016957D0 (en) 2020-10-26 2020-10-26 Beneficial treatment
PCT/EP2021/061485 WO2021224146A1 (en) 2020-05-05 2021-04-30 Methylthioninium compounds for use in the treatment of hypoxemia

Publications (2)

Publication Number Publication Date
JP2023524146A true JP2023524146A (ja) 2023-06-08
JP2023524146A5 JP2023524146A5 (https=) 2024-05-13

Family

ID=75887990

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567338A Pending JP2023524146A (ja) 2020-05-05 2021-04-30 低酸素血症の治療に使用されるメチルチオニニウム化合物

Country Status (12)

Country Link
US (1) US20230158040A1 (https=)
EP (1) EP4146225B1 (https=)
JP (1) JP2023524146A (https=)
KR (1) KR20230012515A (https=)
CN (1) CN115916211A (https=)
AU (1) AU2021268465A1 (https=)
CA (1) CA3181388A1 (https=)
ES (1) ES2992641T3 (https=)
MX (1) MX2022013884A (https=)
PL (1) PL4146225T3 (https=)
TW (1) TWI907424B (https=)
WO (1) WO2021224146A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202204185D0 (en) 2022-03-24 2022-05-11 Wista Lab Ltd Oral treatment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009531403A (ja) * 2006-03-29 2009-09-03 ウイスタ・ラボラトリーズ・リミテッド ３，７−ジアミノ−１０ｈ−フェノチアジン塩およびその使用
JP2014505095A (ja) * 2011-02-11 2014-02-27 ウィスタ ラボラトリーズ リミテッド フェノチアジンジアミニウム塩およびそれらの使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0017060D0 (en) * 2000-07-11 2000-08-30 Hunter Fleming Ltd Production, stabilisation and use of reduced forms of pharmaceutical compounds
US20060264423A1 (en) 2005-05-20 2006-11-23 Bioenvision, Inc. Methylene Blue Therapy of Viral Disease
JP7073330B2 (ja) * 2016-07-25 2022-05-23 ウィスタ ラボラトリーズ リミテッド ジアミノフェノチアジンの投与及び投与量
GB201614834D0 (en) * 2016-09-01 2016-10-19 Wista Lab Ltd Treatment of dementia
FI4385512T3 (fi) * 2018-07-26 2026-01-12 Taurx Therapeutics Man Ltd Diaminofenotiatsiinien optimoitu annostus populaatioille
EP3982974A4 (en) * 2019-06-12 2023-06-21 Achal Narendrakumar Agrawal NOVEL IMPROVED PROCESS FOR THE SYNTHESIS OF DIAMINOPHENOTHIAZINE COMPOUNDS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009531403A (ja) * 2006-03-29 2009-09-03 ウイスタ・ラボラトリーズ・リミテッド ３，７−ジアミノ−１０ｈ−フェノチアジン塩およびその使用
JP2014505095A (ja) * 2011-02-11 2014-02-27 ウィスタ ラボラトリーズ リミテッド フェノチアジンジアミニウム塩およびそれらの使用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ARCHIVES OF BONE AND JOINT SURGERY, vol. 8, JPN6025018474, April 2020 (2020-04-01), pages 1, ISSN: 0005705316 *
MEDICINE, vol. 44, no. 2, JPN6025018473, 2016, pages 91 - 92, ISSN: 0005705315 *
SOUTHERN MEDICAL JOURNAL, vol. 104, no. 11, JPN6025018475, 2011, pages 757 - 761, ISSN: 0005705317 *

Also Published As

Publication number Publication date
EP4146225B1 (en) 2024-10-09
TW202200149A (zh) 2022-01-01
BR112022022322A2 (pt) 2022-12-13
ES2992641T3 (en) 2024-12-16
TWI907424B (zh) 2025-12-11
CN115916211A (zh) 2023-04-04
MX2022013884A (es) 2022-11-30
WO2021224146A1 (en) 2021-11-11
US20230158040A1 (en) 2023-05-25
PL4146225T3 (pl) 2025-03-10
AU2021268465A1 (en) 2022-12-08
EP4146225C0 (en) 2024-10-09
EP4146225A1 (en) 2023-03-15
KR20230012515A (ko) 2023-01-26
CA3181388A1 (en) 2021-11-11

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