JP2023522234A5 - - Google Patents
Info
- Publication number
- JP2023522234A5 JP2023522234A5 JP2022563942A JP2022563942A JP2023522234A5 JP 2023522234 A5 JP2023522234 A5 JP 2023522234A5 JP 2022563942 A JP2022563942 A JP 2022563942A JP 2022563942 A JP2022563942 A JP 2022563942A JP 2023522234 A5 JP2023522234 A5 JP 2023522234A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- substituted
- sequence number
- acid position
- arginine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20170405 | 2020-04-20 | ||
| EP20170405.3 | 2020-04-20 | ||
| PCT/EP2021/059861 WO2021213903A1 (en) | 2020-04-20 | 2021-04-16 | Terminal deoxynucleotidyl transferase variants and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023522234A JP2023522234A (ja) | 2023-05-29 |
| JP2023522234A5 true JP2023522234A5 (https=) | 2024-04-25 |
Family
ID=70390759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022563942A Withdrawn JP2023522234A (ja) | 2020-04-20 | 2021-04-16 | 末端デオキシヌクレオチジルトランスフェラーゼ変異体およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230159903A1 (https=) |
| EP (1) | EP4139446A1 (https=) |
| JP (1) | JP2023522234A (https=) |
| KR (1) | KR20230002825A (https=) |
| CN (1) | CN115427559A (https=) |
| AU (1) | AU2021260014A1 (https=) |
| CA (1) | CA3175780A1 (https=) |
| IL (1) | IL297425A (https=) |
| WO (1) | WO2021213903A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021058438A1 (en) | 2019-09-23 | 2021-04-01 | Dna Script | Increasing long-sequence yields in template-free enzymatic synthesis of polynucleotides |
| CA3234383A1 (en) | 2021-10-15 | 2023-04-27 | Codexis, Inc. | Engineered terminal deoxynucleotidyl transferase variants |
| WO2023187214A1 (en) | 2022-03-31 | 2023-10-05 | Ribbon Biolabs Gmbh | Biopolymer synthesis |
| EP4735621A1 (en) | 2023-06-30 | 2026-05-06 | DNA Script | Nucleic acid synthesis on reusable support |
| GB2635104A (en) * | 2023-09-08 | 2025-05-07 | Evonetix Ltd | Enzymes and methods |
| WO2025088024A1 (en) * | 2023-10-24 | 2025-05-01 | Dna Script | Novel terminal deoxynucleotidyl transferase (tdt) variants and uses thereof |
| US20250313876A1 (en) | 2024-04-06 | 2025-10-09 | Ribbon Bio GmbH | Isolation of dna fragments |
| WO2026008711A2 (en) | 2024-07-02 | 2026-01-08 | Dna Script | Filtering device and method for polynucleotide enzymatic synthesis |
| WO2026008717A2 (en) | 2024-07-02 | 2026-01-08 | Dna Script | Method for enzymatic synthesis of polynucleotides |
| WO2026017834A1 (en) | 2024-07-19 | 2026-01-22 | Dna Script | Inkjet-assisted enzymatic nucleic acid synthesis and cleavage |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5367066A (en) | 1984-10-16 | 1994-11-22 | Chiron Corporation | Oligonucleotides with selectably cleavable and/or abasic sites |
| WO1991006678A1 (en) | 1989-10-26 | 1991-05-16 | Sri International | Dna sequencing |
| US5436143A (en) | 1992-12-23 | 1995-07-25 | Hyman; Edward D. | Method for enzymatic synthesis of oligonucleotides |
| AU1436995A (en) | 1993-12-30 | 1995-07-17 | Chemgenes Corporation | Synthesis of propargyl modified nucleosides and phosphoramidites and their incorporation into defined sequence oligonucleotides |
| EP0776330B1 (en) | 1994-06-23 | 2003-08-20 | Affymax Technologies N.V. | Photolabile compounds and methods for their use |
| US5808045A (en) | 1994-09-02 | 1998-09-15 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
| US5763594A (en) | 1994-09-02 | 1998-06-09 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| US5830655A (en) | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
| EP0967217B1 (en) | 1998-06-22 | 2005-12-21 | Affymetrix, Inc. (a California Corporation) | Reagents and methods for solid phase synthesis and display |
| ATE296310T1 (de) | 1999-03-08 | 2005-06-15 | Metrigen Inc | Syntheseverfahren zum ökonomischen aufbau langer dna-sequenzen und zusammensetzungen hierfür |
| US6664097B2 (en) | 2000-05-23 | 2003-12-16 | North Carolina State University | Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US20060086538A1 (en) | 2002-07-08 | 2006-04-27 | Shell Oil Company | Choke for controlling the flow of drilling mud |
| US7947817B2 (en) | 2003-06-30 | 2011-05-24 | Roche Molecular Systems, Inc. | Synthesis and compositions of 2'-terminator nucleotides |
| US8212020B2 (en) | 2005-03-11 | 2012-07-03 | Steven Albert Benner | Reagents for reversibly terminating primer extension |
| US7544794B1 (en) | 2005-03-11 | 2009-06-09 | Steven Albert Benner | Method for sequencing DNA and RNA by synthesis |
| WO2008042067A2 (en) | 2006-09-28 | 2008-04-10 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
| US8034923B1 (en) | 2009-03-27 | 2011-10-11 | Steven Albert Benner | Reagents for reversibly terminating primer extension |
| EP2876166B1 (en) | 2013-11-20 | 2016-12-14 | Roche Diagnostics GmbH | New compound for sequencing by synthesis |
| FR3020071B1 (fr) * | 2014-04-17 | 2017-12-22 | Dna Script | Procede de synthese d'acides nucleiques, notamment d'acides nucleiques de grande longueur, utilisation du procede et kit pour la mise en œuvre du procede |
| GB201502152D0 (en) * | 2015-02-10 | 2015-03-25 | Nuclera Nucleics Ltd | Novel use |
| FR3052462A1 (fr) | 2016-06-14 | 2017-12-15 | Dna Script | Variants d'une adn polymerase de la famille polx |
| US10472383B2 (en) | 2017-03-16 | 2019-11-12 | Steven A Benner | Nucleoside triphosphates with stable aminoxy groups |
| AU2018272302A1 (en) * | 2017-05-26 | 2019-12-19 | Nuclera Nucleics Ltd | Use of terminal transferase enzyme in nucleic acid synthesis |
| US20190078065A1 (en) | 2017-09-08 | 2019-03-14 | Sigma-Aldrich Co. Llc | Modified dna polymerases |
| US10435676B2 (en) * | 2018-01-08 | 2019-10-08 | Dna Script | Variants of terminal deoxynucleotidyl transferase and uses thereof |
| US10752887B2 (en) * | 2018-01-08 | 2020-08-25 | Dna Script | Variants of terminal deoxynucleotidyl transferase and uses thereof |
| CA3119845A1 (en) * | 2018-11-14 | 2020-05-22 | Dna Script | Terminal deoxynucleotidyl transferase variants and uses thereof |
| SG11202105441WA (en) * | 2018-12-13 | 2021-06-29 | Dna Script | Direct oligonucleotide synthesis on cells and biomolecules |
| WO2020165137A1 (en) * | 2019-02-12 | 2020-08-20 | Dna Script | Efficient product cleavage in template-free enzymatic synthesis of polynucleotides. |
-
2021
- 2021-04-16 US US17/919,649 patent/US20230159903A1/en active Pending
- 2021-04-16 AU AU2021260014A patent/AU2021260014A1/en not_active Abandoned
- 2021-04-16 WO PCT/EP2021/059861 patent/WO2021213903A1/en not_active Ceased
- 2021-04-16 EP EP21717925.8A patent/EP4139446A1/en active Pending
- 2021-04-16 JP JP2022563942A patent/JP2023522234A/ja not_active Withdrawn
- 2021-04-16 KR KR1020227040201A patent/KR20230002825A/ko not_active Withdrawn
- 2021-04-16 CN CN202180029834.3A patent/CN115427559A/zh active Pending
- 2021-04-16 CA CA3175780A patent/CA3175780A1/en active Pending
-
2022
- 2022-10-19 IL IL297425A patent/IL297425A/en unknown
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