JP2023521564A - コロナウイルス科ウイルス感染症を処置又は予防する為の化合物及びコロナウイルス科ウイルス感染症の発生を評価する方法及び使用方法 - Google Patents
コロナウイルス科ウイルス感染症を処置又は予防する為の化合物及びコロナウイルス科ウイルス感染症の発生を評価する方法及び使用方法 Download PDFInfo
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
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- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
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- Pathology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20305299.8A EP3881844A1 (en) | 2020-03-20 | 2020-03-20 | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| EP20305299.8 | 2020-03-20 | ||
| EP20305327.7A EP3884946A1 (en) | 2020-03-25 | 2020-03-25 | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| EP20305327.7 | 2020-03-25 | ||
| EP20305482 | 2020-05-12 | ||
| EP20305482.0 | 2020-05-12 | ||
| EP20306483.7 | 2020-12-03 | ||
| EP20306483 | 2020-12-03 | ||
| PCT/EP2021/057123 WO2021186053A1 (en) | 2020-03-20 | 2021-03-19 | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023521564A true JP2023521564A (ja) | 2023-05-25 |
| JP2023521564A5 JP2023521564A5 (https=) | 2024-03-29 |
| JPWO2021186053A5 JPWO2021186053A5 (https=) | 2024-03-29 |
Family
ID=74884979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556017A Pending JP2023521564A (ja) | 2020-03-20 | 2021-03-19 | コロナウイルス科ウイルス感染症を処置又は予防する為の化合物及びコロナウイルス科ウイルス感染症の発生を評価する方法及び使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230142547A1 (https=) |
| EP (1) | EP4121053A1 (https=) |
| JP (1) | JP2023521564A (https=) |
| KR (1) | KR20220152292A (https=) |
| CN (1) | CN115605205A (https=) |
| AU (1) | AU2021238792A1 (https=) |
| BR (1) | BR112022018793A2 (https=) |
| CA (1) | CA3172179A1 (https=) |
| IL (1) | IL296522A (https=) |
| MX (1) | MX2022011596A (https=) |
| WO (1) | WO2021186053A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023126951A1 (en) * | 2022-01-03 | 2023-07-06 | Yeda Research And Development Co. Ltd. | Inhibitors of autophagy-related protein-protein interactions |
| CN118373771A (zh) * | 2023-01-20 | 2024-07-23 | 江苏柯菲平医药股份有限公司 | 一种喹啉衍生化合物或其可药用的盐及其制备方法和应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018505909A (ja) * | 2015-02-23 | 2018-03-01 | アビバックス | ウィルス感染の処置又は予防において使用する為のキノリン誘導体 |
| JP2018507215A (ja) * | 2015-02-23 | 2018-03-15 | アビバックス | ウィルス感染の処置及び予防において使用する為の新規なキノリン誘導体 |
| JP2023519035A (ja) * | 2020-04-05 | 2023-05-10 | ファイザー・インク | Covid-19を処置するための化合物および方法 |
| JP2023522811A (ja) * | 2020-01-31 | 2023-06-01 | アビバックス | 8-クロロ-n-(4-(トリフルオロメトキシ)フェニル)キノリン-2-アミンの共結晶及びその塩 |
| JP2023532163A (ja) * | 2020-01-31 | 2023-07-27 | アビバックス | 8-クロロ-n-(4-(トリフルオロメトキシ)フェニル)キノリン-2-アミンの非晶質固体分散物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070225363A1 (en) | 2003-11-21 | 2007-09-27 | The University Of Newcastle Research Associates Ltd. | Methods and Agents for Inhibiting Dynamin-Dependent Endocytosis |
| SI2440547T1 (sl) | 2009-06-12 | 2023-05-31 | Abivax | Nove kemične molekule, ki zavirajo mehanizem spajanja za zdravljenje bolezni, ki so posledica napak pri spajanju |
| EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
| EP2862928A1 (en) | 2013-10-18 | 2015-04-22 | Université de Strasbourg | Dynamin 2 inhibitor for the treatment of centronuclear myopathies |
| EP3594206A1 (en) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-quinoline derivatives for treating a rna virus infection |
-
2021
- 2021-03-19 US US17/913,063 patent/US20230142547A1/en active Pending
- 2021-03-19 JP JP2022556017A patent/JP2023521564A/ja active Pending
- 2021-03-19 BR BR112022018793A patent/BR112022018793A2/pt unknown
- 2021-03-19 MX MX2022011596A patent/MX2022011596A/es unknown
- 2021-03-19 CN CN202180034076.4A patent/CN115605205A/zh active Pending
- 2021-03-19 CA CA3172179A patent/CA3172179A1/en active Pending
- 2021-03-19 AU AU2021238792A patent/AU2021238792A1/en not_active Abandoned
- 2021-03-19 IL IL296522A patent/IL296522A/en unknown
- 2021-03-19 KR KR1020227035066A patent/KR20220152292A/ko not_active Ceased
- 2021-03-19 EP EP21712534.3A patent/EP4121053A1/en active Pending
- 2021-03-19 WO PCT/EP2021/057123 patent/WO2021186053A1/en not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018505909A (ja) * | 2015-02-23 | 2018-03-01 | アビバックス | ウィルス感染の処置又は予防において使用する為のキノリン誘導体 |
| JP2018507215A (ja) * | 2015-02-23 | 2018-03-15 | アビバックス | ウィルス感染の処置及び予防において使用する為の新規なキノリン誘導体 |
| JP2023522811A (ja) * | 2020-01-31 | 2023-06-01 | アビバックス | 8-クロロ-n-(4-(トリフルオロメトキシ)フェニル)キノリン-2-アミンの共結晶及びその塩 |
| JP2023532163A (ja) * | 2020-01-31 | 2023-07-27 | アビバックス | 8-クロロ-n-(4-(トリフルオロメトキシ)フェニル)キノリン-2-アミンの非晶質固体分散物 |
| JP2023519035A (ja) * | 2020-04-05 | 2023-05-10 | ファイザー・インク | Covid-19を処置するための化合物および方法 |
Non-Patent Citations (4)
| Title |
|---|
| CALLAWAY E. ET AL., NATURE, vol. 577, JPN6025011664, 30 January 2020 (2020-01-30), pages 605 - 607, ISSN: 0005692671 * |
| CAMPOS N. ET AL., RETROVIROLOGY, vol. 12:30, JPN6025011669, 2015, ISSN: 0005692673 * |
| CLINICALTRIALS.GOV ID NCT04393038: ""ABX464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19", CLINICALTRIALS.GOV [ONLINE], JPN6025011670, 18 May 2020 (2020-05-18), ISSN: 0005557899 * |
| VAUTRIN A. ET AL., SCIENTIFIC REPORTS, vol. 9:792, JPN6025011667, 2019, ISSN: 0005692672 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4121053A1 (en) | 2023-01-25 |
| AU2021238792A1 (en) | 2022-10-13 |
| BR112022018793A2 (pt) | 2022-11-29 |
| WO2021186053A1 (en) | 2021-09-23 |
| CA3172179A1 (en) | 2021-09-23 |
| KR20220152292A (ko) | 2022-11-15 |
| MX2022011596A (es) | 2022-10-18 |
| CN115605205A (zh) | 2023-01-13 |
| US20230142547A1 (en) | 2023-05-11 |
| IL296522A (en) | 2022-11-01 |
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