JP2023521147A5 - - Google Patents
Info
- Publication number
- JP2023521147A5 JP2023521147A5 JP2022561637A JP2022561637A JP2023521147A5 JP 2023521147 A5 JP2023521147 A5 JP 2023521147A5 JP 2022561637 A JP2022561637 A JP 2022561637A JP 2022561637 A JP2022561637 A JP 2022561637A JP 2023521147 A5 JP2023521147 A5 JP 2023521147A5
- Authority
- JP
- Japan
- Prior art keywords
- chimeric polypeptide
- domain
- polypeptide according
- cell
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063007807P | 2020-04-09 | 2020-04-09 | |
| US63/007,807 | 2020-04-09 | ||
| US202163165588P | 2021-03-24 | 2021-03-24 | |
| US63/165,588 | 2021-03-24 | ||
| PCT/US2021/026430 WO2021207526A1 (en) | 2020-04-09 | 2021-04-08 | Humanized notch receptors with hinge domain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023521147A JP2023521147A (ja) | 2023-05-23 |
| JP2023521147A5 true JP2023521147A5 (enExample) | 2024-04-17 |
| JP7863331B2 JP7863331B2 (ja) | 2026-05-21 |
Family
ID=78023652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022561637A Active JP7863331B2 (ja) | 2020-04-09 | 2021-04-08 | ヒンジドメインを有するヒト化ｎｏｔｃｈ受容体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12662675B2 (enExample) |
| EP (1) | EP4132659A4 (enExample) |
| JP (1) | JP7863331B2 (enExample) |
| KR (1) | KR20220166833A (enExample) |
| CN (1) | CN115666726A (enExample) |
| AU (1) | AU2021251212A1 (enExample) |
| BR (1) | BR112022020415A2 (enExample) |
| CA (1) | CA3179954A1 (enExample) |
| IL (1) | IL297092A (enExample) |
| WO (1) | WO2021207526A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2024003887A (es) | 2021-10-14 | 2024-07-09 | Arsenal Biosciences Inc | Células inmunitarias que tienen arnch coespresados y sistemas de compuerta lógica. |
| TW202442689A (zh) | 2023-03-03 | 2024-11-01 | 美商亞森諾生物科學公司 | 靶向ｐｓｍａ及ｃａ９之系統 |
| EP4680748A1 (en) | 2023-03-13 | 2026-01-21 | Arsenal Biosciences, Inc. | Synthetic pathway activators |
| EP4701654A2 (en) * | 2023-04-25 | 2026-03-04 | Arsenal Biosciences, Inc. | Novel receptors for transcription regulation |
| WO2026055533A1 (en) * | 2024-09-06 | 2026-03-12 | The Regents Of The University Of California | Synthetic receptors for engineered ligands |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6333167B1 (en) * | 2000-03-10 | 2001-12-25 | American Home Products Corp. | Methods and reagents for identifying inhibitors of proteolysis of membrane-associated proteins |
| CN103502466A (zh) * | 2010-09-07 | 2014-01-08 | 斯隆－凯特林纪念癌症中心 | 用于γ-分泌酶测定的方法和组合物 |
| ES2769574T3 (es) * | 2013-03-15 | 2020-06-26 | Michael C Milone | Reconocimiento de células citotóxicas con receptores quiméricos para inmunoterapia adoptiva |
| SG10201808811QA (en) | 2014-04-10 | 2018-11-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Method and compositions for cellular immunotherapy |
| EP3262166A4 (en) * | 2015-02-24 | 2018-08-15 | The Regents of The University of California | Binding-triggered transcriptional switches and methods of use thereof |
| CN115094062A (zh) | 2015-04-16 | 2022-09-23 | 埃默里大学 | 用于肝脏中蛋白质表达的重组启动子和载体及其用途 |
| CA3034093A1 (en) * | 2016-08-23 | 2018-03-01 | The Regents Of The University Of California | Proteolytically cleavable chimeric polypeptides and methods of use thereof |
| US11325957B2 (en) | 2017-06-19 | 2022-05-10 | Cell Design Labs, Inc. | Methods and compositions for reducing the immunogenicity of chimeric notch receptors |
| JP2020532987A (ja) | 2017-09-08 | 2020-11-19 | ポセイダ セラピューティクス，インコーポレイティド | キメラリガンド受容体（ｃｌｒ）介在性の条件遺伝子発現のための組成物および方法 |
| KR102742741B1 (ko) | 2017-10-18 | 2024-12-16 | 프레시전 인코포레이티드 | 스페이서를 포함하는 폴리펩타이드 조성물 |
| WO2019217913A1 (en) | 2018-05-10 | 2019-11-14 | Sensei Biotherapeutics, Inc. | Aspartate beta-hydroxylase chimeric antigen receptors and uses thereof |
| GB201818816D0 (en) | 2018-11-19 | 2019-01-02 | Synpromics Ltd | Regulatory nucleic acid sequences |
| CA3120014A1 (en) | 2018-11-19 | 2020-05-28 | Uniqure Ip B.V. | Liver-specific viral promoters and methods of using the same |
| WO2021061791A1 (en) | 2019-09-24 | 2021-04-01 | The Regents Of The University Of California | Notch receptors with zinc finger-containing transcriptional effector |
| US20220372101A1 (en) | 2019-09-24 | 2022-11-24 | The Regents Of The University Of California | Novel receptors having a heterologous stop transfer sequence for ligand-dependent transcriptional regulation |
| US20220340637A1 (en) | 2019-09-24 | 2022-10-27 | The Regents Of The University Of California | Notch receptors with minimal linker |
| WO2021061862A1 (en) * | 2019-09-24 | 2021-04-01 | The Regents Of The University Of California | Notch receptors with hinge domain |
| CN114728174A (zh) | 2019-09-24 | 2022-07-08 | 加利福尼亚大学董事会 | 具有异源跨膜结构域的受体 |
| AU2021256845A1 (en) | 2020-04-14 | 2022-11-24 | Eidgenössische Technische Hochschule Zürich | Cell classifier circuits and methods of use thereof |
| WO2022117686A1 (en) | 2020-12-01 | 2022-06-09 | ETH Zürich | Dna constructs comprising alternative promoters |
| WO2022140159A1 (en) | 2020-12-24 | 2022-06-30 | Kite Pharma, Inc. | Prostate cancer chimeric antigen receptors |
-
2021
- 2021-04-08 WO PCT/US2021/026430 patent/WO2021207526A1/en not_active Ceased
- 2021-04-08 CA CA3179954A patent/CA3179954A1/en active Pending
- 2021-04-08 KR KR1020227038985A patent/KR20220166833A/ko active Pending
- 2021-04-08 EP EP21785532.9A patent/EP4132659A4/en active Pending
- 2021-04-08 CN CN202180039079.7A patent/CN115666726A/zh active Pending
- 2021-04-08 JP JP2022561637A patent/JP7863331B2/ja active Active
- 2021-04-08 BR BR112022020415A patent/BR112022020415A2/pt unknown
- 2021-04-08 US US17/995,751 patent/US12662675B2/en active Active
- 2021-04-08 IL IL297092A patent/IL297092A/en unknown
- 2021-04-08 AU AU2021251212A patent/AU2021251212A1/en active Pending
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