JP2022548796A5 - - Google Patents
Info
- Publication number
- JP2022548796A5 JP2022548796A5 JP2022518818A JP2022518818A JP2022548796A5 JP 2022548796 A5 JP2022548796 A5 JP 2022548796A5 JP 2022518818 A JP2022518818 A JP 2022518818A JP 2022518818 A JP2022518818 A JP 2022518818A JP 2022548796 A5 JP2022548796 A5 JP 2022548796A5
- Authority
- JP
- Japan
- Prior art keywords
- chimeric polypeptide
- cell
- polypeptide according
- sequence
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025171960A JP2026047360A (ja) | 2019-09-24 | 2025-10-10 | ヒンジドメインを有するノッチ受容体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962905263P | 2019-09-24 | 2019-09-24 | |
| US201962905251P | 2019-09-24 | 2019-09-24 | |
| US62/905,263 | 2019-09-24 | ||
| US62/905,251 | 2019-09-24 | ||
| PCT/US2020/052327 WO2021061862A1 (en) | 2019-09-24 | 2020-09-23 | Notch receptors with hinge domain |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025171960A Division JP2026047360A (ja) | 2019-09-24 | 2025-10-10 | ヒンジドメインを有するノッチ受容体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022548796A JP2022548796A (ja) | 2022-11-21 |
| JP2022548796A5 true JP2022548796A5 (enExample) | 2023-10-03 |
Family
ID=75167117
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022518818A Pending JP2022548796A (ja) | 2019-09-24 | 2020-09-23 | ヒンジドメインを有するノッチ受容体 |
| JP2025171960A Pending JP2026047360A (ja) | 2019-09-24 | 2025-10-10 | ヒンジドメインを有するノッチ受容体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025171960A Pending JP2026047360A (ja) | 2019-09-24 | 2025-10-10 | ヒンジドメインを有するノッチ受容体 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11202801B2 (enExample) |
| EP (2) | EP4034252B1 (enExample) |
| JP (2) | JP2022548796A (enExample) |
| KR (1) | KR20220087454A (enExample) |
| CN (2) | CN114761084B (enExample) |
| AU (1) | AU2020355031B2 (enExample) |
| BR (1) | BR112022005283A2 (enExample) |
| CA (1) | CA3155661A1 (enExample) |
| DK (1) | DK4034252T3 (enExample) |
| ES (1) | ES3008682T3 (enExample) |
| FI (1) | FI4034252T3 (enExample) |
| HR (1) | HRP20250135T1 (enExample) |
| HU (1) | HUE069963T2 (enExample) |
| IL (2) | IL291558B2 (enExample) |
| LT (1) | LT4034252T (enExample) |
| PL (1) | PL4034252T3 (enExample) |
| PT (1) | PT4034252T (enExample) |
| RS (1) | RS66476B1 (enExample) |
| SI (1) | SI4034252T1 (enExample) |
| SM (1) | SMT202500031T1 (enExample) |
| WO (1) | WO2021061862A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021061862A1 (en) | 2019-09-24 | 2021-04-01 | The Regents Of The University Of California | Notch receptors with hinge domain |
| WO2021207526A1 (en) * | 2020-04-09 | 2021-10-14 | The Regents Of The University Of California | Humanized notch receptors with hinge domain |
| CA3213044A1 (en) * | 2021-03-23 | 2022-09-29 | Kole T. ROYBAL | Synthetic intermembrane proteolysis receptors for custom antigen-induced transcriptional regulation |
| MX2024003887A (es) | 2021-10-14 | 2024-07-09 | Arsenal Biosciences Inc | Células inmunitarias que tienen arnch coespresados y sistemas de compuerta lógica. |
| US20250017963A1 (en) * | 2021-12-07 | 2025-01-16 | The Regents Of The University Of California | Synthetic cytokine circuits to promote infiltration and clearance of immune excluded solid tumors by engineered immune cells |
| CN114349840B (zh) * | 2021-12-13 | 2024-07-12 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 一种融合蛋白及其制备方法与应用 |
| CN114621929B (zh) * | 2021-12-21 | 2023-05-30 | 河南省肿瘤医院 | 一种抗肿瘤树突状细胞及其制备方法、表达载体及应用 |
| AU2023273025A1 (en) * | 2022-05-16 | 2024-11-28 | The Regents Of The University Of California | T cell activation responsive constructs for enhanced car-t cell therapy |
| TW202442689A (zh) | 2023-03-03 | 2024-11-01 | 美商亞森諾生物科學公司 | 靶向ｐｓｍａ及ｃａ９之系統 |
| EP4680748A1 (en) | 2023-03-13 | 2026-01-21 | Arsenal Biosciences, Inc. | Synthetic pathway activators |
| WO2024249416A2 (en) * | 2023-06-01 | 2024-12-05 | Vanderbilt University | Engineered cells to detect and respond to amyloid beta peptides |
| CN117304343B (zh) * | 2023-10-11 | 2024-05-07 | 北京景达生物科技有限公司 | Gpc3靶向的car-nk细胞的制备及其应用 |
| CN120248130B (zh) * | 2023-12-28 | 2026-05-26 | 上海恩凯细胞技术有限公司 | 特异性靶向肿瘤的转基因重组免疫细胞及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0781095T3 (da) * | 1994-08-02 | 2003-06-23 | Gen Hospital Corp | Celler der bærer CD4 lokkeduereceptorer og beslægtede molekyler og fremgangsmåder |
| NZ759969A (en) * | 2013-12-20 | 2022-12-23 | Fred Hutchinson Cancer Center | Tagged chimeric effector molecules and receptors thereof |
| EP3262166A4 (en) * | 2015-02-24 | 2018-08-15 | The Regents of The University of California | Binding-triggered transcriptional switches and methods of use thereof |
| WO2017123559A2 (en) * | 2016-01-11 | 2017-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric proteins and methods of regulating gene expression |
| CA3034093A1 (en) * | 2016-08-23 | 2018-03-01 | The Regents Of The University Of California | Proteolytically cleavable chimeric polypeptides and methods of use thereof |
| WO2018132427A1 (en) * | 2017-01-10 | 2018-07-19 | The General Hospital Corporation | Targeted t cells with cytotoxicity toward immunosuppressive cells |
| US11325957B2 (en) * | 2017-06-19 | 2022-05-10 | Cell Design Labs, Inc. | Methods and compositions for reducing the immunogenicity of chimeric notch receptors |
| US10724680B2 (en) * | 2017-07-06 | 2020-07-28 | Robert Anthony Benson, SR. | Personal device holder |
| KR102742741B1 (ko) * | 2017-10-18 | 2024-12-16 | 프레시전 인코포레이티드 | 스페이서를 포함하는 폴리펩타이드 조성물 |
| WO2021061862A1 (en) | 2019-09-24 | 2021-04-01 | The Regents Of The University Of California | Notch receptors with hinge domain |
-
2020
- 2020-09-23 WO PCT/US2020/052327 patent/WO2021061862A1/en not_active Ceased
- 2020-09-23 HR HRP20250135TT patent/HRP20250135T1/hr unknown
- 2020-09-23 RS RS20250107A patent/RS66476B1/sr unknown
- 2020-09-23 JP JP2022518818A patent/JP2022548796A/ja active Pending
- 2020-09-23 SI SI202030570T patent/SI4034252T1/sl unknown
- 2020-09-23 ES ES20869739T patent/ES3008682T3/es active Active
- 2020-09-23 CN CN202080080098.XA patent/CN114761084B/zh active Active
- 2020-09-23 EP EP20869739.1A patent/EP4034252B1/en active Active
- 2020-09-23 SM SM20250031T patent/SMT202500031T1/it unknown
- 2020-09-23 BR BR112022005283A patent/BR112022005283A2/pt unknown
- 2020-09-23 PT PT208697391T patent/PT4034252T/pt unknown
- 2020-09-23 PL PL20869739.1T patent/PL4034252T3/pl unknown
- 2020-09-23 DK DK20869739.1T patent/DK4034252T3/da active
- 2020-09-23 IL IL291558A patent/IL291558B2/en unknown
- 2020-09-23 IL IL307609A patent/IL307609B2/en unknown
- 2020-09-23 CA CA3155661A patent/CA3155661A1/en active Pending
- 2020-09-23 FI FIEP20869739.1T patent/FI4034252T3/fi active
- 2020-09-23 AU AU2020355031A patent/AU2020355031B2/en active Active
- 2020-09-23 HU HUE20869739A patent/HUE069963T2/hu unknown
- 2020-09-23 EP EP24200385.3A patent/EP4461748A3/en active Pending
- 2020-09-23 LT LTEPPCT/US2020/052327T patent/LT4034252T/lt unknown
- 2020-09-23 CN CN202311362358.4A patent/CN119569894A/zh active Pending
- 2020-09-23 KR KR1020227013693A patent/KR20220087454A/ko active Pending
-
2021
- 2021-03-30 US US17/217,618 patent/US11202801B2/en active Active
- 2021-11-17 US US17/529,091 patent/US11617766B2/en active Active
-
2023
- 2023-03-03 US US18/178,440 patent/US20240075062A1/en active Pending
-
2025
- 2025-10-10 JP JP2025171960A patent/JP2026047360A/ja active Pending
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