JP2023519101A5 - - Google Patents
Info
- Publication number
- JP2023519101A5 JP2023519101A5 JP2022548612A JP2022548612A JP2023519101A5 JP 2023519101 A5 JP2023519101 A5 JP 2023519101A5 JP 2022548612 A JP2022548612 A JP 2022548612A JP 2022548612 A JP2022548612 A JP 2022548612A JP 2023519101 A5 JP2023519101 A5 JP 2023519101A5
- Authority
- JP
- Japan
- Prior art keywords
- grna
- nucleic acid
- sequence
- exon
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062975636P | 2020-02-12 | 2020-02-12 | |
| US62/975,636 | 2020-02-12 | ||
| PCT/US2021/017942 WO2021163550A1 (en) | 2020-02-12 | 2021-02-12 | Haplotype-based treatment of rp1 associated retinal degenerations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023519101A JP2023519101A (ja) | 2023-05-10 |
| JP2023519101A5 true JP2023519101A5 (https=) | 2024-02-21 |
Family
ID=77292955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548612A Pending JP2023519101A (ja) | 2020-02-12 | 2021-02-12 | Ｒｐ１関連網膜変性症のハプロタイプに基づく処置 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12129496B2 (https=) |
| EP (1) | EP4103238A4 (https=) |
| JP (1) | JP2023519101A (https=) |
| CN (1) | CN115427568A (https=) |
| AU (1) | AU2021219795A1 (https=) |
| WO (1) | WO2021163550A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12171813B2 (en) | 2021-02-05 | 2024-12-24 | Christiana Care Gene Editing Institute, Inc. | Methods of and compositions for reducing gene expression and/or activity |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3023787A1 (de) | 1980-06-25 | 1982-01-21 | Studiengesellschaft Kohle mbH, 4330 Mülheim | Verfahren zur erhoehung der inkorporation und der expression von genetischem material in die kerne von intakten zellen mit hilfe von liposomen |
| JPS57124055A (en) | 1981-01-27 | 1982-08-02 | Toyota Motor Corp | Air-fuel ratio control device for engine |
| IL79289A (en) | 1985-07-05 | 1992-01-15 | Whitehead Biomedical Inst | Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus |
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| ATE117375T1 (de) | 1987-09-11 | 1995-02-15 | Whitehead Biomedical Inst | Transduktionsveränderte fibroblasten und ihre anwendung. |
| JP2914692B2 (ja) | 1987-12-11 | 1999-07-05 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 内皮細胞の遺伝子修飾 |
| WO1989007136A2 (en) | 1988-02-05 | 1989-08-10 | Whitehead Institute For Biomedical Research | Modified hepatocytes and uses therefor |
| EP0452457B1 (en) | 1989-11-03 | 1997-08-20 | Vanderbilt University | Method of in vivo delivery of functioning foreign genes |
| ES2096750T3 (es) | 1990-10-31 | 1997-03-16 | Somatix Therapy Corp | Vectores retroviricos utiles para la terapia genica. |
| CN112301024A (zh) | 2013-03-15 | 2021-02-02 | 通用医疗公司 | 使用RNA引导的FokI核酸酶(RFN)提高RNA引导的基因组编辑的特异性 |
| CN106232618A (zh) | 2013-10-11 | 2016-12-14 | 马萨诸塞眼科耳科诊所 | 预测祖先病毒序列的方法及其用途 |
| KR20230156800A (ko) | 2015-03-03 | 2023-11-14 | 더 제너럴 하스피탈 코포레이션 | 변경된 PAM 특이성을 갖는 조작된 CRISPR-Cas9 뉴클레아제 |
| JP6799586B2 (ja) | 2015-08-28 | 2020-12-16 | ザ ジェネラル ホスピタル コーポレイション | 遺伝子操作ＣＲＩＳＰＲ−Ｃａｓ９ヌクレアーゼ |
| BR112019001887A2 (pt) | 2016-08-02 | 2019-07-09 | Editas Medicine Inc | composições e métodos para o tratamento de doença associada a cep290 |
| US20190345501A1 (en) * | 2017-02-07 | 2019-11-14 | Massachusetts Institute Of Technology | Methods and compositions for rna-guided genetic circuits |
| US11591589B2 (en) | 2017-04-21 | 2023-02-28 | The General Hospital Corporation | Variants of Cpf1 (Cas12a) with altered PAM specificity |
| US20210032612A1 (en) * | 2018-02-22 | 2021-02-04 | Avellino Lab Usa, Inc. | CRISPR/Cas9 Systems, and Methods of Use Thereof |
| CN112153990A (zh) * | 2018-03-23 | 2020-12-29 | 纽约市哥伦比亚大学理事会 | 用于常染色体显性疾病的基因编辑 |
| BR112020019079A2 (pt) * | 2018-03-23 | 2020-12-29 | Massachusetts Eye And Ear Infirmary | Abordagem de salto de éxon mediada por crispr/cas9 para síndrome de usher associada a ush2a |
-
2021
- 2021-02-12 CN CN202180027183.4A patent/CN115427568A/zh active Pending
- 2021-02-12 EP EP21753483.3A patent/EP4103238A4/en active Pending
- 2021-02-12 WO PCT/US2021/017942 patent/WO2021163550A1/en not_active Ceased
- 2021-02-12 AU AU2021219795A patent/AU2021219795A1/en active Pending
- 2021-02-12 JP JP2022548612A patent/JP2023519101A/ja active Pending
- 2021-02-12 US US17/175,234 patent/US12129496B2/en active Active
-
2024
- 2024-09-19 US US18/890,708 patent/US20250115887A1/en active Pending
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