JP2023519100A5 - - Google Patents

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Publication number
JP2023519100A5
JP2023519100A5 JP2022548596A JP2022548596A JP2023519100A5 JP 2023519100 A5 JP2023519100 A5 JP 2023519100A5 JP 2022548596 A JP2022548596 A JP 2022548596A JP 2022548596 A JP2022548596 A JP 2022548596A JP 2023519100 A5 JP2023519100 A5 JP 2023519100A5
Authority
JP
Japan
Prior art keywords
antibody
seq
group
antigen
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022548596A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023519100A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/017427 external-priority patent/WO2021163170A1/en
Publication of JP2023519100A publication Critical patent/JP2023519100A/ja
Publication of JP2023519100A5 publication Critical patent/JP2023519100A5/ja
Pending legal-status Critical Current

Links

JP2022548596A 2020-02-11 2021-02-10 抗acvr1抗体およびその使用 Pending JP2023519100A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062975047P 2020-02-11 2020-02-11
US62/975,047 2020-02-11
US202063030131P 2020-05-26 2020-05-26
US63/030,131 2020-05-26
PCT/US2021/017427 WO2021163170A1 (en) 2020-02-11 2021-02-10 Anti-acvr1 antibodies and uses thereof

Publications (2)

Publication Number Publication Date
JP2023519100A JP2023519100A (ja) 2023-05-10
JP2023519100A5 true JP2023519100A5 (enExample) 2024-02-22

Family

ID=74860418

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548596A Pending JP2023519100A (ja) 2020-02-11 2021-02-10 抗acvr1抗体およびその使用

Country Status (11)

Country Link
US (2) US11945872B2 (enExample)
EP (1) EP4103617A1 (enExample)
JP (1) JP2023519100A (enExample)
KR (1) KR20220140802A (enExample)
CN (1) CN115362175A (enExample)
AU (1) AU2021218675A1 (enExample)
CA (1) CA3167441A1 (enExample)
IL (1) IL295419A (enExample)
MX (1) MX2022009769A (enExample)
WO (1) WO2021163170A1 (enExample)
ZA (1) ZA202208222B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113366019B (zh) 2018-10-23 2024-08-27 科乐斯疗法公司 Alk2抗体及其使用方法
US12508262B2 (en) 2020-04-30 2025-12-30 Keros Therapeutics, Inc. Methods of using ALK2 inhibitors
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
TW202328190A (zh) * 2021-09-03 2023-07-16 大陸商來凱醫藥科技(上海)有限公司 抗acvr2a抗體及其用途
WO2024092133A1 (en) 2022-10-27 2024-05-02 Regeneron Pharmaceuticals, Inc. Anti-acvr1 antibodies and their use in the treatment of trauma-induced heterotopic ossification

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
US20040101920A1 (en) 2002-11-01 2004-05-27 Czeslaw Radziejewski Modification assisted profiling (MAP) methodology
US7850962B2 (en) 2004-04-20 2010-12-14 Genmab A/S Human monoclonal antibodies against CD20
US8257740B1 (en) 2011-08-15 2012-09-04 Gp Medical, Inc. Pharmaceutical composition of nanoparticles
US8246995B2 (en) 2005-05-10 2012-08-21 The Board Of Trustees Of The Leland Stanford Junior University Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells
CA2649770C (en) 2006-04-18 2017-08-15 The Trustees Of The University Of Pennsylvania Mutated acvr1 for diagnosis and treatment of fibrodysplasia ossificans progressiva (fop)
US8859752B2 (en) 2006-04-18 2014-10-14 The Trustees Of The University Of Pennsylvania SIRNA-based therapy of Fibrodyplasia Ossificans Progressiva (FOP)
JP5307708B2 (ja) 2006-06-02 2013-10-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド ヒトil−6受容体に対する高親和性抗体
JP5642972B2 (ja) * 2007-02-21 2014-12-17 ユニバーシティー オブ マサチューセッツUniversity of Massachusetts C型肝炎ウイルス(hcv)に対するヒト抗体およびその使用
MY192182A (en) 2009-06-26 2022-08-04 Regeneron Pharma Readily isolated bispecific antibodies with native immunoglobulin format
SMT202600080T1 (it) 2010-02-08 2026-03-09 Regeneron Pharma Topo con catena leggera comune
TWI635098B (zh) 2013-02-01 2018-09-11 再生元醫藥公司 含嵌合恆定區之抗體
TW201920262A (zh) 2013-07-30 2019-06-01 美商再生元醫藥公司 抗活化素a之抗體及其用途
TWI703156B (zh) * 2015-01-30 2020-09-01 學校法人埼玉醫科大學 抗alk2抗體
MX2020008582A (es) 2018-03-05 2020-09-21 Univ Saitama Medical Composicion farmaceutica para tratar o prevenir la osificacion heterotopica.
AU2019310590A1 (en) * 2018-07-26 2021-01-14 Sumitomo Pharma Oncology, Inc. Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
CN113366019B (zh) 2018-10-23 2024-08-27 科乐斯疗法公司 Alk2抗体及其使用方法
WO2020118011A1 (en) 2018-12-06 2020-06-11 Alexion Pharmaceuticals, Inc. Anti-alk2 antibodies and uses thereof
EP4008350A4 (en) 2019-07-26 2023-06-14 Saitama Medical University ANTIBODY RECOGNIZING THE EXTRACELLULAR REGION OF ALK2/ACVR1

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