JP2023516748A5 - - Google Patents

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Publication number
JP2023516748A5
JP2023516748A5 JP2022553196A JP2022553196A JP2023516748A5 JP 2023516748 A5 JP2023516748 A5 JP 2023516748A5 JP 2022553196 A JP2022553196 A JP 2022553196A JP 2022553196 A JP2022553196 A JP 2022553196A JP 2023516748 A5 JP2023516748 A5 JP 2023516748A5
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pharmaceutical composition
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JP2022553196A
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JP7802676B2 (ja
JP2023516748A (ja
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Priority claimed from PCT/US2021/021049 external-priority patent/WO2021178778A1/en
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JP2022553196A 2020-03-06 2021-03-05 トランスサイレチン(ttr)の発現を阻害するための組成物および方法 Active JP7802676B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062985950P 2020-03-06 2020-03-06
US62/985,950 2020-03-06
PCT/US2021/021049 WO2021178778A1 (en) 2020-03-06 2021-03-05 Compositions and methods for inhibiting expression of transthyretin (ttr)

Publications (3)

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JP2023516748A JP2023516748A (ja) 2023-04-20
JP2023516748A5 true JP2023516748A5 (https=) 2024-03-14
JP7802676B2 JP7802676B2 (ja) 2026-01-20

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JP2022553196A Active JP7802676B2 (ja) 2020-03-06 2021-03-05 トランスサイレチン(ttr)の発現を阻害するための組成物および方法

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EP (1) EP4114949A1 (https=)
JP (1) JP7802676B2 (https=)
KR (1) KR20220152270A (https=)
CN (1) CN115461460A (https=)
AU (1) AU2021232029A1 (https=)
CA (1) CA3174473A1 (https=)
IL (1) IL296106A (https=)
WO (1) WO2021178778A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX360460B (es) 2008-10-20 2018-11-05 Alnylam Pharmaceuticals Inc Composiciones y metodos para inhibir la expresion de transtiretina.
PT3329002T (pt) 2015-07-31 2021-01-12 Alnylam Pharmaceuticals Inc Composições de iarn de transtirretina (ttr) e métodos de seu uso para tratamento ou prevenção de doenças associadas à ttr
BR112020005230A2 (pt) 2017-09-19 2020-09-24 Alnylam Pharmaceuticals, Inc. composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr)
CA3227852A1 (en) 2021-08-03 2023-02-09 Alnylam Pharmaceuticals, Inc. Transthyretin (ttr) irna compositions and methods of use thereof
JP2025541245A (ja) * 2022-12-16 2025-12-18 アムジェン インコーポレイテッド Ttr発現を阻害するためのrnaiコンストラクト及びその使用方法
WO2025077916A1 (zh) * 2023-10-13 2025-04-17 北京安龙生物医药有限公司 靶向转甲状腺素蛋白的寡核苷酸及其用途
WO2025098117A1 (zh) * 2023-11-06 2025-05-15 成都倍特药业股份有限公司 一种抑制甲状腺素转运蛋白(TTR)表达的RNAi试剂、组合物及应用

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