JP2023513752A5 - - Google Patents

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Publication number
JP2023513752A5
JP2023513752A5 JP2022548955A JP2022548955A JP2023513752A5 JP 2023513752 A5 JP2023513752 A5 JP 2023513752A5 JP 2022548955 A JP2022548955 A JP 2022548955A JP 2022548955 A JP2022548955 A JP 2022548955A JP 2023513752 A5 JP2023513752 A5 JP 2023513752A5
Authority
JP
Japan
Prior art keywords
protein
cancer
fragment
polynucleotide according
pathway
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022548955A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023513752A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2021/001904 external-priority patent/WO2021162521A1/ko
Publication of JP2023513752A publication Critical patent/JP2023513752A/ja
Publication of JP2023513752A5 publication Critical patent/JP2023513752A5/ja
Pending legal-status Critical Current

Links

JP2022548955A 2020-02-14 2021-02-15 外部から導入された細胞シグナル伝達調節因子を過剰発現する免疫細胞及びその使用 Pending JP2023513752A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20200018169 2020-02-14
KR10-2020-0018169 2020-02-14
PCT/KR2021/001904 WO2021162521A1 (ko) 2020-02-14 2021-02-15 외부에서 도입된 세포 신호 조절 인자를 과발현하는 면역 세포 및 이들의 용도

Publications (2)

Publication Number Publication Date
JP2023513752A JP2023513752A (ja) 2023-04-03
JP2023513752A5 true JP2023513752A5 (https=) 2024-02-26

Family

ID=77291621

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548955A Pending JP2023513752A (ja) 2020-02-14 2021-02-15 外部から導入された細胞シグナル伝達調節因子を過剰発現する免疫細胞及びその使用

Country Status (8)

Country Link
US (1) US20230212254A1 (https=)
EP (1) EP4105232A4 (https=)
JP (1) JP2023513752A (https=)
KR (1) KR20210103975A (https=)
CN (1) CN115427451B (https=)
AU (1) AU2021219233A1 (https=)
TW (1) TW202146440A (https=)
WO (1) WO2021162521A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4472742A1 (en) * 2022-02-03 2024-12-11 University College Cardiff Consultants Limited Novel t-cell receptor
CN114774364B (zh) * 2022-04-26 2024-04-26 深圳市体内生物医药科技有限公司 一种嵌合抗原受体t细胞及其制备方法和应用
WO2024121426A1 (en) * 2022-12-09 2024-06-13 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh Method for optimizing t cells for immuno-therapy
IL322949A (en) 2023-03-03 2025-10-01 Arsenal Biosciences Inc Systems targeting PSMA and CA9
CN116376844B (zh) * 2023-05-31 2023-08-11 四川大学华西医院 包含shp2 sh2结构域的靶向her2阳性肿瘤的car-t及制备方法和应用
CN116355859B (zh) * 2023-05-31 2023-08-11 四川大学华西医院 包含shp2 n-sh2结构域的靶向her2阳性肿瘤的car-t及制备方法和应用
CN116814664B (zh) * 2023-08-25 2023-12-12 中国医学科学院肿瘤医院 一种扩展肿瘤识别表位的cea嵌合抗原受体t细胞的制备与应用
WO2025111277A2 (en) * 2023-11-20 2025-05-30 Carisma Therapeutics Inc. Compositions and methods relating to redirected soluble modulators

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002098897A2 (en) 2001-06-01 2002-12-12 Cornell Research Foundation, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
DK2956175T3 (da) * 2013-02-15 2017-11-27 Univ California Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf
SI3597742T1 (sl) * 2014-10-09 2022-11-30 Yamaguchi University CAR ekspresijski vektor in T celice, ki izražajo CAR
CN109863242A (zh) * 2016-08-30 2019-06-07 纪念斯隆-凯特林癌症中心 用于治疗病毒感染和其它感染的免疫细胞组合物和使用方法
MA46862A (fr) * 2016-11-17 2019-09-25 Bluebird Bio Inc Convertisseur de signaux tgf béta
GB201620070D0 (en) * 2016-11-28 2017-01-11 Autolus Ltd Signal transduction modifying protein
SG11201906552WA (en) * 2017-01-25 2019-08-27 Tessa Therapeutics Pte Ltd TGF-ß DECOY RECEPTOR
US20190381171A1 (en) * 2017-02-17 2019-12-19 Unum Therapeutics Inc. Co-use of anti-bcma antibody and antibody-coupled t cell receptor (actr) in cancer therapy and b cell disorders
KR102746901B1 (ko) * 2017-03-03 2024-12-26 옵시디안 테라퓨틱스, 인크. Cd19 조성물 및 면역요법을 위한 방법
CN110831619A (zh) * 2017-03-22 2020-02-21 诺华股份有限公司 具有增强功效的生物标志和car t细胞疗法
CA3287539A1 (en) * 2017-06-21 2026-03-02 Icell Gene Therapeutics Llc CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF
CN108218999B (zh) * 2018-01-02 2021-06-11 广东省人民医院(广东省医学科学院) 分泌il-7的嵌合抗原受体、病毒载体、表达细胞及制备方法与药物
CN109265565B (zh) * 2018-10-10 2021-06-01 苏州大学 一种携带分子开关的抗CD79b嵌合抗原受体及其修饰的免疫细胞和应用
WO2020123947A1 (en) * 2018-12-14 2020-06-18 Bluebird Bio, Inc. Dimerizing agent regulated immunoreceptor complexes

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