JP2023512786A5 - - Google Patents
Info
- Publication number
- JP2023512786A5 JP2023512786A5 JP2022547882A JP2022547882A JP2023512786A5 JP 2023512786 A5 JP2023512786 A5 JP 2023512786A5 JP 2022547882 A JP2022547882 A JP 2022547882A JP 2022547882 A JP2022547882 A JP 2022547882A JP 2023512786 A5 JP2023512786 A5 JP 2023512786A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heterocycloalkenyl
- substituents
- independently selected
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025035491A JP2025087835A (ja) | 2020-02-07 | 2025-03-06 | Ｎａｍｐｔモジュレーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062971838P | 2020-02-07 | 2020-02-07 | |
| US62/971,838 | 2020-02-07 | ||
| PCT/US2021/016948 WO2021159015A1 (en) | 2020-02-07 | 2021-02-05 | Nampt modulators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025035491A Division JP2025087835A (ja) | 2020-02-07 | 2025-03-06 | Ｎａｍｐｔモジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023512786A JP2023512786A (ja) | 2023-03-29 |
| JP2023512786A5 true JP2023512786A5 (enExample) | 2024-02-13 |
| JP7681030B2 JP7681030B2 (ja) | 2025-05-21 |
Family
ID=74858766
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022547882A Active JP7681030B2 (ja) | 2020-02-07 | 2021-02-05 | Ｎａｍｐｔモジュレーター |
| JP2025035491A Pending JP2025087835A (ja) | 2020-02-07 | 2025-03-06 | Ｎａｍｐｔモジュレーター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025035491A Pending JP2025087835A (ja) | 2020-02-07 | 2025-03-06 | Ｎａｍｐｔモジュレーター |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20230133132A1 (enExample) |
| EP (1) | EP4100393A1 (enExample) |
| JP (2) | JP7681030B2 (enExample) |
| KR (1) | KR20220152537A (enExample) |
| CN (1) | CN115515934B (enExample) |
| AR (1) | AR121282A1 (enExample) |
| AU (1) | AU2021217402A1 (enExample) |
| BR (1) | BR112022014728A2 (enExample) |
| CA (1) | CA3168838A1 (enExample) |
| CL (1) | CL2022002106A1 (enExample) |
| CO (1) | CO2022012773A2 (enExample) |
| IL (2) | IL321884A (enExample) |
| MX (1) | MX2022009771A (enExample) |
| PH (1) | PH12022552021A1 (enExample) |
| TW (1) | TWI908763B (enExample) |
| WO (1) | WO2021159015A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4263524A1 (en) | 2020-12-21 | 2023-10-25 | Cytokinetics, Inc. | Pyrazole derivatives useful as nampt modulators |
| JP2025542258A (ja) | 2022-12-22 | 2025-12-25 | サイトキネティックス， インコーポレイテッド | Ｎａｍｐｔモジュレーター |
| WO2025243724A1 (ja) * | 2024-05-20 | 2025-11-27 | 国立研究開発法人国立精神・神経医療研究センター | 神経保護剤 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100477070B1 (ko) | 1994-03-25 | 2006-04-21 | 이소테크니카 인코포레이티드 | 중수소화작용에의한의약품의효능강화법 |
| US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| PT1037880E (pt) | 1997-12-11 | 2004-11-30 | Janssen Pharmaceutica Nv | Anilidas mimeticas do acido retinoico |
| DE10208986A1 (de) | 2002-02-28 | 2003-09-11 | Aventis Pharma Gmbh | Verwendung substituierter 3-Phenyl-5-alkoxi-1,3,4-oxdiazol-2-one zur Herstellung von Arzneimitteln mit hemmender Wirkung an der pankreatischen Lipase |
| TW200503994A (en) * | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
| CN101253152A (zh) | 2005-09-02 | 2008-08-27 | 安斯泰来制药株式会社 | 作为rock抑制剂的酰胺衍生物 |
| WO2007084667A2 (en) | 2006-01-19 | 2007-07-26 | Osi Pharmaceutical, Inc. | Fused heterobicyclic kinase inhibitors |
| US20130317027A1 (en) | 2010-03-01 | 2013-11-28 | Myrexis, Inc. | Compounds and therapeutic uses thereof |
| BR112012021806A2 (pt) | 2010-03-01 | 2015-09-08 | Myrexis Inc | compostos e seus usos terapêusticos. |
| US9132136B2 (en) | 2010-08-02 | 2015-09-15 | Hoffmann-La Roche Inc. | Pharmaceutical combination |
| CN106986856A (zh) | 2010-09-03 | 2017-07-28 | 福马Tm有限责任公司 | 作为用于治疗疾病诸如癌症的nampt抑制剂的4‑{[(吡啶‑3‑基‑甲基)氨基羰基]氨基}苯‑砜衍生物 |
| JP6318156B2 (ja) | 2012-09-06 | 2018-04-25 | プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． | キナーゼをモジュレートするための化合物および方法、ならびにその指標 |
| US11452717B2 (en) * | 2017-01-10 | 2022-09-27 | Sanford Burnham Prebys Medical Discovery Institute | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof |
| CN106916101B (zh) | 2017-02-15 | 2020-05-01 | 聚缘（上海）生物科技有限公司 | Nampt/hdac双靶点抑制剂及其制备方法 |
-
2021
- 2021-02-05 CN CN202180021899.3A patent/CN115515934B/zh active Active
- 2021-02-05 PH PH1/2022/552021A patent/PH12022552021A1/en unknown
- 2021-02-05 US US17/798,296 patent/US20230133132A1/en active Pending
- 2021-02-05 MX MX2022009771A patent/MX2022009771A/es unknown
- 2021-02-05 EP EP21710105.4A patent/EP4100393A1/en active Pending
- 2021-02-05 CA CA3168838A patent/CA3168838A1/en active Pending
- 2021-02-05 IL IL321884A patent/IL321884A/en unknown
- 2021-02-05 WO PCT/US2021/016948 patent/WO2021159015A1/en not_active Ceased
- 2021-02-05 KR KR1020227031227A patent/KR20220152537A/ko active Pending
- 2021-02-05 JP JP2022547882A patent/JP7681030B2/ja active Active
- 2021-02-05 BR BR112022014728A patent/BR112022014728A2/pt unknown
- 2021-02-05 AU AU2021217402A patent/AU2021217402A1/en active Pending
- 2021-02-05 AR ARP210100313A patent/AR121282A1/es unknown
- 2021-02-05 IL IL295296A patent/IL295296A/en unknown
- 2021-02-08 TW TW110104511A patent/TWI908763B/zh active
-
2022
- 2022-08-04 CL CL2022002106A patent/CL2022002106A1/es unknown
- 2022-09-07 CO CONC2022/0012773A patent/CO2022012773A2/es unknown
-
2025
- 2025-03-06 JP JP2025035491A patent/JP2025087835A/ja active Pending
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