JP2023512501A5 - - Google Patents
Info
- Publication number
- JP2023512501A5 JP2023512501A5 JP2022544188A JP2022544188A JP2023512501A5 JP 2023512501 A5 JP2023512501 A5 JP 2023512501A5 JP 2022544188 A JP2022544188 A JP 2022544188A JP 2022544188 A JP2022544188 A JP 2022544188A JP 2023512501 A5 JP2023512501 A5 JP 2023512501A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- val
- compound according
- cit
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062964180P | 2020-01-22 | 2020-01-22 | |
| US62/964,180 | 2020-01-22 | ||
| US202063085414P | 2020-09-30 | 2020-09-30 | |
| US63/085,414 | 2020-09-30 | ||
| PCT/EP2021/051263 WO2021148501A1 (en) | 2020-01-22 | 2021-01-21 | Compounds and conjugates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023512501A JP2023512501A (ja) | 2023-03-27 |
| JP2023512501A5 true JP2023512501A5 (enExample) | 2024-01-19 |
Family
ID=74418415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022544188A Withdrawn JP2023512501A (ja) | 2020-01-22 | 2021-01-21 | 化合物及びその複合体 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20230111996A1 (enExample) |
| EP (1) | EP4093438A1 (enExample) |
| JP (1) | JP2023512501A (enExample) |
| KR (1) | KR20220130191A (enExample) |
| CN (1) | CN115052633A (enExample) |
| AU (1) | AU2021211892A1 (enExample) |
| BR (1) | BR112022013966A2 (enExample) |
| CA (1) | CA3167373A1 (enExample) |
| CO (1) | CO2022011178A2 (enExample) |
| CR (1) | CR20220393A (enExample) |
| EC (1) | ECSP22064855A (enExample) |
| IL (1) | IL294645A (enExample) |
| MX (1) | MX2022008997A (enExample) |
| TW (1) | TW202140076A (enExample) |
| WO (1) | WO2021148501A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3241157A1 (en) | 2021-12-16 | 2023-06-22 | Wei Zhou | Camptothecin compound and conjugate thereof |
| CN115160403B (zh) * | 2022-07-05 | 2025-06-27 | 博石丰生命科技(南通)有限公司 | 特异性拓扑异构酶抑制剂和可用于抗体药物偶联物及其制备方法 |
| CA3261603A1 (en) | 2022-07-15 | 2024-01-18 | Pheon Therapeutics Ltd | ANTIBODY-DRUG CONJUGATES |
| EP4309676A1 (en) * | 2022-07-22 | 2024-01-24 | Emergence Therapeutics AG | Novel anti-nectin-4 antibody camptothecin derivative conjugates |
| KR20250057869A (ko) * | 2022-09-07 | 2025-04-29 | 잭세라 바이오파마슈티컬 (수조우) 씨오., 엘티디. | 항-trop2/egfr 항체 및 이의 용도 |
| CN119630672B (zh) * | 2023-02-23 | 2026-01-30 | 一线医药（杭州）有限公司 | 喜树碱衍生物及其偶联物以及其制备方法和医药用途 |
| AU2024271903A1 (en) * | 2023-05-12 | 2025-10-09 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Linker compounds and ligand-drug conjugates, preparation methods and uses thereof |
| KR20260020468A (ko) | 2023-06-05 | 2026-02-11 | 장쑤 맵웰 헬스 파마수티컬 알앤디 컴퍼니, 리미티드 | 항-b7-h3 항체 또는 그 단편 및 b7-h3를 표적으로 하는 항체 약물 접합체(anti-b7-h3 antibody or fragment thereof, and antibody drug conjugate targeting b7-h3) |
| WO2025103192A1 (zh) * | 2023-11-16 | 2025-05-22 | 上海齐鲁制药研究中心有限公司 | 一种氘代喜树碱化合物及其制备和应用 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4939255A (en) | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| DK1791565T3 (en) | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
| SI1934174T1 (sl) | 2005-10-07 | 2011-08-31 | Exelixis Inc | Inhibitorji MEK in postopki za njihovo uporabo |
| RS52060B (sr) | 2006-01-25 | 2012-04-30 | Sanofi | Citotoksični agensi koji sadrže nove derivate tomaimicina |
| CL2008001334A1 (es) | 2007-05-08 | 2008-09-22 | Genentech Inc | Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer. |
| NZ584514A (en) | 2007-10-19 | 2012-07-27 | Genentech Inc | Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates |
| GB201506393D0 (en) * | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| MA43354A (fr) * | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| AU2017359155A1 (en) | 2016-11-10 | 2019-06-13 | Medimmune, Llc | Binding molecules specific for ASCT2 and uses thereof |
| MX2021011812A (es) * | 2019-03-29 | 2021-10-22 | Medimmune Ltd | Compuestos y conjugados de estos. |
| BR112023004415A2 (pt) * | 2020-09-11 | 2023-05-09 | Medimmune Ltd | Moléculas terapêuticas de ligação a b7-h4 |
-
2021
- 2021-01-20 TW TW110102103A patent/TW202140076A/zh unknown
- 2021-01-21 MX MX2022008997A patent/MX2022008997A/es unknown
- 2021-01-21 CN CN202180010204.1A patent/CN115052633A/zh active Pending
- 2021-01-21 IL IL294645A patent/IL294645A/en unknown
- 2021-01-21 AU AU2021211892A patent/AU2021211892A1/en not_active Abandoned
- 2021-01-21 BR BR112022013966A patent/BR112022013966A2/pt not_active IP Right Cessation
- 2021-01-21 EP EP21702401.7A patent/EP4093438A1/en not_active Withdrawn
- 2021-01-21 CR CR20220393A patent/CR20220393A/es unknown
- 2021-01-21 JP JP2022544188A patent/JP2023512501A/ja not_active Withdrawn
- 2021-01-21 KR KR1020227028554A patent/KR20220130191A/ko active Pending
- 2021-01-21 WO PCT/EP2021/051263 patent/WO2021148501A1/en not_active Ceased
- 2021-01-21 CA CA3167373A patent/CA3167373A1/en active Pending
- 2021-01-21 US US17/759,078 patent/US20230111996A1/en not_active Abandoned
-
2022
- 2022-08-08 CO CONC2022/0011178A patent/CO2022011178A2/es unknown
- 2022-08-18 EC ECSENADI202264855A patent/ECSP22064855A/es unknown
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