JP2023512455A5 - - Google Patents
Info
- Publication number
- JP2023512455A5 JP2023512455A5 JP2022542684A JP2022542684A JP2023512455A5 JP 2023512455 A5 JP2023512455 A5 JP 2023512455A5 JP 2022542684 A JP2022542684 A JP 2022542684A JP 2022542684 A JP2022542684 A JP 2022542684A JP 2023512455 A5 JP2023512455 A5 JP 2023512455A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- optionally substituted
- conjugate
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062959882P | 2020-01-10 | 2020-01-10 | |
| US202062959877P | 2020-01-10 | 2020-01-10 | |
| US202062959862P | 2020-01-10 | 2020-01-10 | |
| US62/959,882 | 2020-01-10 | ||
| US62/959,862 | 2020-01-10 | ||
| US62/959,877 | 2020-01-10 | ||
| US202063043754P | 2020-06-24 | 2020-06-24 | |
| US202063043752P | 2020-06-24 | 2020-06-24 | |
| US202063043749P | 2020-06-24 | 2020-06-24 | |
| US63/043,752 | 2020-06-24 | ||
| US63/043,749 | 2020-06-24 | ||
| US63/043,754 | 2020-06-24 | ||
| PCT/US2021/012846 WO2021142377A2 (en) | 2020-01-10 | 2021-01-08 | Cell surface receptor binding compounds and conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023512455A JP2023512455A (ja) | 2023-03-27 |
| JP2023512455A5 true JP2023512455A5 (https=) | 2024-01-16 |
Family
ID=76788318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022542684A Withdrawn JP2023512455A (ja) | 2020-01-10 | 2021-01-08 | 細胞表面受容体結合化合物およびコンジュゲート |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230158155A1 (https=) |
| EP (1) | EP4087584A4 (https=) |
| JP (1) | JP2023512455A (https=) |
| KR (1) | KR20220144893A (https=) |
| CN (1) | CN115315263A (https=) |
| AU (1) | AU2021206280A1 (https=) |
| CA (1) | CA3167272A1 (https=) |
| IL (1) | IL294564A (https=) |
| WO (1) | WO2021142377A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12485178B2 (en) | 2018-04-09 | 2025-12-02 | Yale University | Bifunctional small molecules to target the selective degradation of circulating proteins |
| EP3773727A4 (en) | 2018-04-09 | 2022-05-04 | Yale University | BIFUNCTIONAL SMALL MOLECULES TO TARGETING THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS |
| US20230097887A1 (en) | 2018-04-09 | 2023-03-30 | Yale University | Bi-functional Molecules to Degrade Circulating Proteins |
| KR20220099963A (ko) * | 2019-10-10 | 2022-07-14 | 예일 유니버시티 | 세포 수용체를 통한 분자 분해제로서의 조작된 항체 |
| WO2021155317A1 (en) | 2020-01-31 | 2021-08-05 | Avilar Therapeutics, Inc. | Asgpr-binding compounds for the degradation of extracellular proteins |
| KR20240017423A (ko) | 2021-05-03 | 2024-02-07 | 아빌라 테라퓨틱스, 인크. | 이뮤노글로불린 및 다른 단백질의 분해를 위한 강력한 asgpr-결합 화합물 |
| EP4370157A1 (en) | 2021-07-14 | 2024-05-22 | Lycia Therapeutics, Inc. | Asgpr cell surface receptor binding compounds and conjugates |
| AU2022310346A1 (en) | 2021-07-14 | 2024-01-25 | Lycia Therapeutics, Inc. | M6pr cell surface receptor binding compounds and conjugates |
| WO2023028590A1 (en) * | 2021-08-27 | 2023-03-02 | Yale University | Molecular degraders of extracellular proteins |
| EP4293785B1 (en) | 2021-11-12 | 2026-03-25 | LG Energy Solution, Ltd. | Non-aqueous electrolyte solution for lithium secondary battery, and lithium secondary battery comprising same |
| FR3132634B1 (fr) * | 2022-02-15 | 2025-04-25 | Nanomedsyn | Composés bifonctionnels ciblant le récepteur du mannose 6-phosphate cation-indépendant |
| JP2026503462A (ja) * | 2023-01-18 | 2026-01-29 | ライシア セラピューティクス， インコーポレイテッド | 自己抗体の分解のためのリソソーム標的化二官能性分子 |
| EP4651902A2 (en) * | 2023-01-18 | 2025-11-26 | Lycia Therapeutics, Inc. | Asgpr binding compounds and conjugates |
| CN120835794A (zh) | 2023-01-18 | 2025-10-24 | 利西亚治疗公司 | M6pr结合化合物和缀合物 |
| FR3146400B1 (fr) * | 2023-03-07 | 2026-01-30 | Nanomedsyn | Conjugués ciblant le récepteur du mannose 6-phosphate cation-indépendant et le tissu osseux |
| CN116023273A (zh) * | 2023-03-29 | 2023-04-28 | 思合基因(北京)生物科技有限公司 | 一种新型碳糖苷及其制备方法 |
| CN116854754B (zh) | 2023-09-01 | 2023-12-12 | 北京悦康科创医药科技股份有限公司 | 一种含有核糖环或其衍生结构的GalNAc化合物及其寡核苷酸缀合物 |
| CN117924386B (zh) * | 2023-12-22 | 2024-07-12 | 合肥综合性国家科学中心大健康研究院 | Hpa1降解剂及其制备方法和用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002950217A0 (en) * | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| US20080057072A1 (en) * | 2006-08-31 | 2008-03-06 | Alcon Manufacturing, Ltd. | Antagonists of ci-m6p/igf2r for prevention and treatment of ctgf-mediated ocular disorders |
| US8962573B2 (en) * | 2009-07-03 | 2015-02-24 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Compounds targeting the cation-independent mannose 6-phosphate receptor |
-
2021
- 2021-01-08 US US17/792,027 patent/US20230158155A1/en active Pending
- 2021-01-08 CN CN202180020578.1A patent/CN115315263A/zh active Pending
- 2021-01-08 EP EP21738146.6A patent/EP4087584A4/en active Pending
- 2021-01-08 CA CA3167272A patent/CA3167272A1/en active Pending
- 2021-01-08 WO PCT/US2021/012846 patent/WO2021142377A2/en not_active Ceased
- 2021-01-08 AU AU2021206280A patent/AU2021206280A1/en active Pending
- 2021-01-08 KR KR1020227027658A patent/KR20220144893A/ko active Pending
- 2021-01-08 IL IL294564A patent/IL294564A/en unknown
- 2021-01-08 JP JP2022542684A patent/JP2023512455A/ja not_active Withdrawn
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