JP2023509186A5 - - Google Patents

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Publication number
JP2023509186A5
JP2023509186A5 JP2022541984A JP2022541984A JP2023509186A5 JP 2023509186 A5 JP2023509186 A5 JP 2023509186A5 JP 2022541984 A JP2022541984 A JP 2022541984A JP 2022541984 A JP2022541984 A JP 2022541984A JP 2023509186 A5 JP2023509186 A5 JP 2023509186A5
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JP
Japan
Prior art keywords
pharmaceutical product
alkoxy
alkyl
formula
product according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022541984A
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English (en)
Japanese (ja)
Other versions
JP7763761B2 (ja
JP2023509186A (ja
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Application filed filed Critical
Priority claimed from PCT/IB2021/000006 external-priority patent/WO2021140418A1/en
Publication of JP2023509186A publication Critical patent/JP2023509186A/ja
Publication of JP2023509186A5 publication Critical patent/JP2023509186A5/ja
Application granted granted Critical
Publication of JP7763761B2 publication Critical patent/JP7763761B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022541984A 2020-01-08 2021-01-07 Betブロモドメイン阻害剤およびジペプチジルペプチダーゼ4阻害剤の組合せによる主要有害心血管イベント(mace)の治療方法および/または予防方法 Active JP7763761B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062958474P 2020-01-08 2020-01-08
US62/958,474 2020-01-08
PCT/IB2021/000006 WO2021140418A1 (en) 2020-01-08 2021-01-07 Methods of treatment and/or prevention of major adverse cardiovascular events (mace) with a combination of a bet bromodomain inhibitor and a dipeptidyl peptidase 4 inhibitor

Publications (3)

Publication Number Publication Date
JP2023509186A JP2023509186A (ja) 2023-03-07
JP2023509186A5 true JP2023509186A5 (https=) 2024-01-16
JP7763761B2 JP7763761B2 (ja) 2025-11-04

Family

ID=76788523

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022541984A Active JP7763761B2 (ja) 2020-01-08 2021-01-07 Betブロモドメイン阻害剤およびジペプチジルペプチダーゼ4阻害剤の組合せによる主要有害心血管イベント(mace)の治療方法および/または予防方法

Country Status (9)

Country Link
US (1) US20230241064A1 (https=)
EP (1) EP4087575A4 (https=)
JP (1) JP7763761B2 (https=)
KR (1) KR20220124736A (https=)
CN (1) CN115003306A (https=)
CA (1) CA3164933A1 (https=)
IL (1) IL294344B1 (https=)
TW (1) TWI882058B (https=)
WO (1) WO2021140418A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114650824A (zh) 2019-11-05 2022-06-21 雷斯韦洛吉克斯公司 用bet溴结构域抑制剂和钠依赖性葡萄糖转运蛋白2抑制剂的组合治疗和/或预防主要不良心血管事件(mace)的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2118074E (pt) * 2007-02-01 2014-03-20 Resverlogix Corp Compostos para a prevenção e tratamento de doenças cardiovasculares
MX2011009852A (es) * 2009-03-27 2011-09-29 Bristol Myers Squibb Co Metodos para prevenir episodios cardiovasculares adversos mayores con inhibidores de dipeptidil peptidasa iv.
AR083878A1 (es) * 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
HK1219434A1 (zh) * 2013-08-21 2017-04-07 Resverlogix Corp. 用於加速斑块消退的组合物和治疗方法
AU2014310371A1 (en) * 2013-08-21 2016-03-10 Resverlogix Corp. Compositions and therapeutic methods for accelerated plaque regression
WO2016011335A1 (en) * 2014-07-17 2016-01-21 Jerome Schentag Activation of the endogenous ileal brake hormone pathway for organ regeneration and related compositions, methods of treatment, diagnostics, and regulatory systems
US20190031774A1 (en) * 2017-06-09 2019-01-31 Sanofi Biotechnology Methods for treating hyperlipidemia in diabetic patients by administering a pcsk9 inhibitor
CN109824608B (zh) * 2019-03-15 2022-06-21 深圳晶泰科技有限公司 一种Apabetalone晶型及其制备方法

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