JP2023507848A5 - - Google Patents

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Publication number
JP2023507848A5
JP2023507848A5 JP2022538737A JP2022538737A JP2023507848A5 JP 2023507848 A5 JP2023507848 A5 JP 2023507848A5 JP 2022538737 A JP2022538737 A JP 2022538737A JP 2022538737 A JP2022538737 A JP 2022538737A JP 2023507848 A5 JP2023507848 A5 JP 2023507848A5
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JP
Japan
Prior art keywords
cancer
composition according
lag
cdr
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022538737A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023507848A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/065873 external-priority patent/WO2021133653A1/en
Publication of JP2023507848A publication Critical patent/JP2023507848A/ja
Publication of JP2023507848A5 publication Critical patent/JP2023507848A5/ja
Priority to JP2025154757A priority Critical patent/JP2026001028A/ja
Pending legal-status Critical Current

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JP2022538737A 2019-12-23 2020-12-18 癌の治療のための療法 Pending JP2023507848A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025154757A JP2026001028A (ja) 2019-12-23 2025-09-18 癌の治療のための療法

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201962952859P 2019-12-23 2019-12-23
US201962952878P 2019-12-23 2019-12-23
US62/952,859 2019-12-23
US62/952,878 2019-12-23
US202063019857P 2020-05-04 2020-05-04
US63/019,857 2020-05-04
US202063021556P 2020-05-07 2020-05-07
US63/021,556 2020-05-07
US202063031453P 2020-05-28 2020-05-28
US63/031,453 2020-05-28
US202063123581P 2020-12-10 2020-12-10
US63/123,581 2020-12-10
PCT/US2020/065873 WO2021133653A1 (en) 2019-12-23 2020-12-18 Therapy for the treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025154757A Division JP2026001028A (ja) 2019-12-23 2025-09-18 癌の治療のための療法

Publications (2)

Publication Number Publication Date
JP2023507848A JP2023507848A (ja) 2023-02-27
JP2023507848A5 true JP2023507848A5 (https=) 2023-12-21

Family

ID=76575359

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022538737A Pending JP2023507848A (ja) 2019-12-23 2020-12-18 癌の治療のための療法
JP2025154757A Pending JP2026001028A (ja) 2019-12-23 2025-09-18 癌の治療のための療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025154757A Pending JP2026001028A (ja) 2019-12-23 2025-09-18 癌の治療のための療法

Country Status (13)

Country Link
US (1) US20230056230A1 (https=)
EP (1) EP4081248A4 (https=)
JP (2) JP2023507848A (https=)
KR (1) KR20220119694A (https=)
CN (1) CN114901306A (https=)
AU (1) AU2020412595A1 (https=)
BR (1) BR112022012437A2 (https=)
CA (1) CA3165839A1 (https=)
IL (1) IL294207A (https=)
MX (1) MX2022007790A (https=)
TW (1) TW202138387A (https=)
WO (1) WO2021133653A1 (https=)
ZA (1) ZA202206743B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL295434A (en) * 2020-02-21 2022-10-01 Macrogenics Inc cd137 binding molecules and their uses
KR20230093282A (ko) 2020-10-23 2023-06-27 브리스톨-마이어스 스큅 컴퍼니 폐암에 대한 lag-3 길항제 요법
WO2023279092A2 (en) * 2021-07-02 2023-01-05 Genentech, Inc. Methods and compositions for treating cancer
AU2022317820A1 (en) * 2021-07-28 2023-12-14 F. Hoffmann-La Roche Ag Methods and compositions for treating cancer
JP2024536881A (ja) * 2021-09-29 2024-10-08 中山康方生物医▲藥▼有限公司 抗lag3抗体、医薬組成物、及び使用
WO2023066322A1 (zh) * 2021-10-21 2023-04-27 杭州阿诺生物医药科技有限公司 一种融合多肽及其用途
CN117679505A (zh) * 2022-09-09 2024-03-12 中山康方生物医药有限公司 药物组合及用途
WO2024163009A1 (en) * 2023-01-31 2024-08-08 Genentech, Inc. Methods and compositions for treating urothelial bladder cancer
TW202436339A (zh) * 2023-01-31 2024-09-16 瑞士商赫孚孟拉羅股份公司 治療選自非小細胞肺癌或三陰性乳癌的癌症之用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2542256B1 (en) * 2010-03-04 2019-05-22 MacroGenics, Inc. Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
JP6595458B2 (ja) * 2013-09-20 2019-10-23 ブリストル−マイヤーズ スクイブ カンパニー 腫瘍を処置するための抗lag−3抗体と抗pd−1抗体との組合せ
TWI693232B (zh) * 2014-06-26 2020-05-11 美商宏觀基因股份有限公司 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
TWI773646B (zh) * 2015-06-08 2022-08-11 美商宏觀基因股份有限公司 結合lag-3的分子和其使用方法
HUE068868T2 (hu) * 2015-07-30 2025-02-28 Macrogenics Inc PD-1-hez kötõdõ molekulák és alkalmazásukra szolgáló eljárások
US20190002563A1 (en) * 2015-08-17 2019-01-03 Macrogenics, Inc. Bispecific Monovalent Diabodies That are Capable of Binding B7-H3 and CD3, and Uses Thereof
IL260021B (en) * 2015-12-14 2022-09-01 Macrogenics Inc Bispecific molecules that are immunoreactive for pd1 and ctla4 and methods for using them
GEP20227398B (en) * 2016-04-15 2022-07-25 Macrogenics Inc Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof
MX2018014950A (es) * 2016-06-07 2019-04-25 Macrogenics Inc Terapia de combinacion.
HRP20210602T1 (hr) * 2016-06-20 2021-05-14 F-Star Delta Limited Vezujuće molekule koje vežu pd-l1 i lag-3
US20200148785A1 (en) * 2017-03-29 2020-05-14 Glycotope (GmbH) Pd-l1 and ta-muc1 antibodies
EP4516809A3 (en) * 2017-04-05 2025-09-03 F. Hoffmann-La Roche AG Bispecific antibodies specifically binding to pd1 and lag3
CN110678200B (zh) * 2017-05-30 2024-05-17 百时美施贵宝公司 包含抗lag-3抗体或抗lag-3抗体和抗pd-1或抗pd-l1抗体的组合物
WO2019148412A1 (en) * 2018-02-01 2019-08-08 Merck Sharp & Dohme Corp. Anti-pd-1/lag3 bispecific antibodies
US20210115138A1 (en) * 2018-03-20 2021-04-22 WuXi Biologics Ireland Limited Novel bispecific pd-1/lag-3 antibody molecules

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