JP2023536086A5 - - Google Patents

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Publication number
JP2023536086A5
JP2023536086A5 JP2023505707A JP2023505707A JP2023536086A5 JP 2023536086 A5 JP2023536086 A5 JP 2023536086A5 JP 2023505707 A JP2023505707 A JP 2023505707A JP 2023505707 A JP2023505707 A JP 2023505707A JP 2023536086 A5 JP2023536086 A5 JP 2023536086A5
Authority
JP
Japan
Prior art keywords
cancer
bispecific molecule
ctla
use according
cdr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023505707A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023536086A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/042901 external-priority patent/WO2022026306A1/en
Publication of JP2023536086A publication Critical patent/JP2023536086A/ja
Publication of JP2023536086A5 publication Critical patent/JP2023536086A5/ja
Pending legal-status Critical Current

Links

JP2023505707A 2020-07-27 2021-07-23 Pd‐1×ctla‐4二重特異性分子の使用のための方法 Pending JP2023536086A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063057054P 2020-07-27 2020-07-27
US63/057,054 2020-07-27
US202163177036P 2021-04-20 2021-04-20
US63/177,036 2021-04-20
US202163219066P 2021-07-07 2021-07-07
US63/219,066 2021-07-07
PCT/US2021/042901 WO2022026306A1 (en) 2020-07-27 2021-07-23 Methods for the use of a pd-1 x ctla-4 bispecific molecule

Publications (2)

Publication Number Publication Date
JP2023536086A JP2023536086A (ja) 2023-08-23
JP2023536086A5 true JP2023536086A5 (https=) 2024-07-29

Family

ID=80036053

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023505707A Pending JP2023536086A (ja) 2020-07-27 2021-07-23 Pd‐1×ctla‐4二重特異性分子の使用のための方法

Country Status (13)

Country Link
US (1) US20230312756A1 (https=)
EP (1) EP4188961A4 (https=)
JP (1) JP2023536086A (https=)
KR (1) KR20230042038A (https=)
CN (1) CN116134053A (https=)
AU (1) AU2021316192A1 (https=)
BR (1) BR112023001487A2 (https=)
CA (1) CA3189926A1 (https=)
IL (1) IL300166A (https=)
MX (1) MX2023001111A (https=)
TW (1) TW202220691A (https=)
WO (1) WO2022026306A1 (https=)
ZA (1) ZA202300822B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120648657A (zh) * 2024-03-08 2025-09-16 上海锦斯生物技术有限公司 一种修饰的溶瘤病毒及其组合物
WO2026021409A1 (zh) * 2024-07-22 2026-01-29 宜明昂科生物医药技术(上海)股份有限公司 靶向ctla-4、pd-l1和vegf的肿瘤联合疗法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2439273T3 (da) * 2005-05-09 2019-06-03 Ono Pharmaceutical Co Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika
IL260021B (en) * 2015-12-14 2022-09-01 Macrogenics Inc Bispecific molecules that are immunoreactive for pd1 and ctla4 and methods for using them
AR108377A1 (es) * 2016-05-06 2018-08-15 Medimmune Llc Proteínas de unión biespecíficas y sus usos
JP7010854B2 (ja) * 2016-06-14 2022-01-26 ゼンコア インコーポレイテッド 二重特異性チェックポイント阻害剤抗体
WO2018014260A1 (en) * 2016-07-20 2018-01-25 Nanjing Legend Biotech Co., Ltd. Multispecific antigen binding proteins and methods of use thereof
CN106967172B (zh) * 2016-08-23 2019-01-08 康方药业有限公司 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
WO2019179421A1 (en) * 2018-03-19 2019-09-26 Wuxi Biologics (Shanghai) Co., Ltd. Novel bispecific pd-1/ctla-4 antibody molecules

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