JP2023504186A5 - - Google Patents

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Publication number
JP2023504186A5
JP2023504186A5 JP2022533064A JP2022533064A JP2023504186A5 JP 2023504186 A5 JP2023504186 A5 JP 2023504186A5 JP 2022533064 A JP2022533064 A JP 2022533064A JP 2022533064 A JP2022533064 A JP 2022533064A JP 2023504186 A5 JP2023504186 A5 JP 2023504186A5
Authority
JP
Japan
Prior art keywords
peptide
construct
construct according
hhhk
oligonucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022533064A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023504186A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/063676 external-priority patent/WO2021113851A2/en
Publication of JP2023504186A publication Critical patent/JP2023504186A/ja
Publication of JP2023504186A5 publication Critical patent/JP2023504186A5/ja
Pending legal-status Critical Current

Links

JP2022533064A 2019-12-06 2020-12-07 標的化された核酸送達のためのペプチドドッキング賦形剤 Pending JP2023504186A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962945042P 2019-12-06 2019-12-06
US62/945,042 2019-12-06
PCT/US2020/063676 WO2021113851A2 (en) 2019-12-06 2020-12-07 Peptide docking vehicle for targeted nucleic acid delivery

Publications (2)

Publication Number Publication Date
JP2023504186A JP2023504186A (ja) 2023-02-01
JP2023504186A5 true JP2023504186A5 (enExample) 2024-01-10

Family

ID=76222046

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022533064A Pending JP2023504186A (ja) 2019-12-06 2020-12-07 標的化された核酸送達のためのペプチドドッキング賦形剤

Country Status (11)

Country Link
US (1) US12054714B2 (enExample)
EP (1) EP4069261A4 (enExample)
JP (1) JP2023504186A (enExample)
KR (1) KR20220115579A (enExample)
CN (1) CN114885604B (enExample)
AU (1) AU2020398192A1 (enExample)
BR (1) BR112022010883A2 (enExample)
CA (1) CA3160576A1 (enExample)
IL (1) IL293589A (enExample)
WO (1) WO2021113851A2 (enExample)
ZA (1) ZA202207211B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114716518A (zh) * 2021-01-06 2022-07-08 圣诺制药公司 一种能够抑制pcsk9表达的分子构造及药物组合物
EP4380623A4 (en) * 2021-08-04 2026-05-06 Hepagene Therapeutics Hk Ltd Ligand conjugates for delivery of therapeutically active agents
US20230053360A1 (en) * 2021-08-11 2023-02-23 Nicholas Stephanopoulos Nucleic acid-peptide-nucleic acid conjugate molecules and methods of making the same
CN118450909A (zh) * 2021-09-22 2024-08-06 圣诺制药公司 用于制备含有组氨酸-赖氨酸共聚物的纳米颗粒组合物的改善的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101060849A (zh) * 2004-11-17 2007-10-24 巴尔的摩马里兰大学 作为有效的siRNA载体的高分支HK肽
CA2721183C (en) * 2008-04-11 2019-07-16 Alnylam Pharmaceuticals, Inc. Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
CA2947904A1 (en) * 2015-11-12 2017-05-12 Pfizer Inc. Tissue-specific genome engineering using crispr-cas9
JP2019513371A (ja) * 2016-04-01 2019-05-30 アビディティー バイオサイエンシーズ エルエルシー 核酸ポリペプチド組成物とその使用
WO2018013525A1 (en) * 2016-07-11 2018-01-18 Translate Bio Ma, Inc. Nucleic acid conjugates and uses thereof
RU2019113301A (ru) * 2016-10-17 2020-11-17 Апеллис Фармасьютикалс, Инк. Комбинированная терапия для ингибирования с3
AU2019275071B2 (en) * 2018-05-24 2022-12-15 Sirnaomics, Inc. Composition and methods of controllable co-coupling polypeptide nanoparticle delivery system for nucleic acid therapeutics

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