JP2023503852A5 - - Google Patents
Info
- Publication number
- JP2023503852A5 JP2023503852A5 JP2022527989A JP2022527989A JP2023503852A5 JP 2023503852 A5 JP2023503852 A5 JP 2023503852A5 JP 2022527989 A JP2022527989 A JP 2022527989A JP 2022527989 A JP2022527989 A JP 2022527989A JP 2023503852 A5 JP2023503852 A5 JP 2023503852A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- pyridine
- oxy
- piperidine
- dichlorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962934407P | 2019-11-12 | 2019-11-12 | |
| US62/934,407 | 2019-11-12 | ||
| PCT/US2020/060108 WO2021097009A1 (en) | 2019-11-12 | 2020-11-12 | Small molecule furin inhibitors for treating infectious diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023503852A JP2023503852A (ja) | 2023-02-01 |
| JP2023503852A5 true JP2023503852A5 (https=) | 2023-11-20 |
Family
ID=73793799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022527989A Pending JP2023503852A (ja) | 2019-11-12 | 2020-11-12 | 感染症を処置するための低分子フーリン阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230011571A1 (https=) |
| EP (1) | EP4058021A1 (https=) |
| JP (1) | JP2023503852A (https=) |
| KR (1) | KR20220104744A (https=) |
| CN (1) | CN114929220A (https=) |
| AU (1) | AU2020382819A1 (https=) |
| CA (1) | CA3157892A1 (https=) |
| WO (1) | WO2021097009A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020022961A2 (pt) | 2018-05-11 | 2021-02-17 | Glaxosmithkline Intellectual Property Development Limited | inibidores de furina |
| DE102023126563A1 (de) * | 2023-09-28 | 2025-04-03 | Philipps-Universität Marburg, Körperschaft des öffentlichen Rechts | Hemmstoffe der Proproteinkonvertase Furin, Verfahren zu deren Herstellung und Verwendung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003037346A1 (en) * | 2001-10-31 | 2003-05-08 | Cell Therapeutics, Inc. | 6-phenyl-n-phenyl-(1,3,5) -triazine-2,4-diamine derivatives and related compounds with lysophphosphatidic acid acyltransferase beta (lpaat-beta) inhibitory activity for use in the treatment of cancer |
| EP2478766A3 (en) | 2007-05-09 | 2012-08-15 | Burnham Institute for Medical Research | Targeting host proteinases as a therapeutic strategy against viral and bacterial pathogens |
| US20150051138A1 (en) * | 2012-03-16 | 2015-02-19 | Sanford-Burnham Medical Research Institute | Inhibitors of furin and other pro-protein convertases |
| US10150742B2 (en) * | 2013-03-15 | 2018-12-11 | President And Fellows Of Harvard College | Substituted heterocyclic compounds for treating or preventing viral infections |
| CN107441094B (zh) * | 2017-08-08 | 2020-05-22 | 南方医科大学 | 尼罗替尼作为治疗登革病毒感染的药物及其制药用途 |
| BR112020022961A2 (pt) * | 2018-05-11 | 2021-02-17 | Glaxosmithkline Intellectual Property Development Limited | inibidores de furina |
-
2020
- 2020-11-12 KR KR1020227019647A patent/KR20220104744A/ko not_active Ceased
- 2020-11-12 AU AU2020382819A patent/AU2020382819A1/en active Pending
- 2020-11-12 JP JP2022527989A patent/JP2023503852A/ja active Pending
- 2020-11-12 CA CA3157892A patent/CA3157892A1/en active Pending
- 2020-11-12 CN CN202080092431.9A patent/CN114929220A/zh active Pending
- 2020-11-12 EP EP20823987.1A patent/EP4058021A1/en active Pending
- 2020-11-12 US US17/776,067 patent/US20230011571A1/en not_active Abandoned
- 2020-11-12 WO PCT/US2020/060108 patent/WO2021097009A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021523941A5 (https=) | ||
| AU2023216887B2 (en) | Compounds and methods for the targeted degradation of androgen receptor | |
| IL278642B2 (en) | Purine inhibitors | |
| NL2000323C2 (nl) | Pyrimidine-derivaten. | |
| US10004755B2 (en) | Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity | |
| ES2588680T3 (es) | Compuestos de tiazolopirimidina | |
| JP2019530739A5 (https=) | ||
| KR101702609B1 (ko) | 인플루엔자 바이러스 복제의 억제제 | |
| ES2401192T3 (es) | Deazapurinas útiles como inhibidores de janus cinasas | |
| ES2654051T3 (es) | Pirrolo[2,3-d]pirimidinilo, pirrolo[2,3-b]pirazinilo y pirrolo[2,3-d]piridinil acrilamidas | |
| ES2637295T3 (es) | Compuestos de 6,7-dihidropirazolo[1,5-a]pirazin-4(5h)-ona y su uso como moduladores alostéricos negativos de receptores mGluR2 | |
| RU2675792C2 (ru) | Замещенные гетероциклические сульфонамидные соединения, полезные в качестве модуляторов trpa 1 | |
| RU2399620C2 (ru) | Производные хинуклидина и их применение в качестве антагонистов мускариновых рецепторов м3 | |
| JP2022501338A5 (https=) | ||
| ES2708215T3 (es) | Compuestos de 6,7-dihidropirazolo[1,5-a]pirazin-4(5H)-ona y su uso como moduladores alostéricos negativos de receptores MGLU2 | |
| ES2655971T9 (es) | Compuestos de aminopirimidinilo como inhibidores de JAK | |
| JP2012501312A5 (https=) | ||
| JP2023503852A5 (https=) | ||
| US20140315886A1 (en) | Quinazolines as therapeutic compounds and related methods of use | |
| JP2021502400A (ja) | 置換ピロロピリミジンｊａｋ阻害剤ならびにこれを作製および使用する方法 | |
| JP2003531210A5 (https=) | ||
| EA038235B1 (ru) | Бигетероарильные соединения и их применения | |
| JP2017519733A (ja) | チロシンキナーゼ阻害剤としての置換エチニルヘテロ二環式化合物 | |
| AU2015308522A1 (en) | Products for the treatment and prevention of neurological disorders coursing with a cognition deficit or impairment, and of neurodegenerative diseases | |
| CN110291090A (zh) | 作为新型jak激酶抑制剂的双环胺 |