JP2023502794A5 - - Google Patents

Info

Publication number
JP2023502794A5
JP2023502794A5 JP2022554964A JP2022554964A JP2023502794A5 JP 2023502794 A5 JP2023502794 A5 JP 2023502794A5 JP 2022554964 A JP2022554964 A JP 2022554964A JP 2022554964 A JP2022554964 A JP 2022554964A JP 2023502794 A5 JP2023502794 A5 JP 2023502794A5
Authority
JP
Japan
Prior art keywords
compound according
solvate
salt
alkyl
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022554964A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023502794A (ja
JP7652791B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/082778 external-priority patent/WO2021099518A1/en
Publication of JP2023502794A publication Critical patent/JP2023502794A/ja
Publication of JP2023502794A5 publication Critical patent/JP2023502794A5/ja
Application granted granted Critical
Publication of JP7652791B2 publication Critical patent/JP7652791B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022554964A 2019-11-19 2020-11-19 α-シヌクレインの凝集に関連する疾患の診断、治療および予防のための新規な化合物 Active JP7652791B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19210073 2019-11-19
EP19210073.3 2019-11-19
PCT/EP2020/082778 WO2021099518A1 (en) 2019-11-19 2020-11-19 Novel compounds for the diagnosis, treatment and prevention of diseases associated with the aggregation of alpha-synuclein

Publications (3)

Publication Number Publication Date
JP2023502794A JP2023502794A (ja) 2023-01-25
JP2023502794A5 true JP2023502794A5 (cg-RX-API-DMAC7.html) 2023-04-04
JP7652791B2 JP7652791B2 (ja) 2025-03-27

Family

ID=68834924

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022554964A Active JP7652791B2 (ja) 2019-11-19 2020-11-19 α-シヌクレインの凝集に関連する疾患の診断、治療および予防のための新規な化合物

Country Status (13)

Country Link
US (1) US20230067910A1 (cg-RX-API-DMAC7.html)
EP (2) EP4368184A3 (cg-RX-API-DMAC7.html)
JP (1) JP7652791B2 (cg-RX-API-DMAC7.html)
KR (1) KR20220104000A (cg-RX-API-DMAC7.html)
CN (1) CN114728927B (cg-RX-API-DMAC7.html)
AU (2) AU2020386151B2 (cg-RX-API-DMAC7.html)
BR (1) BR112022008195A2 (cg-RX-API-DMAC7.html)
CA (1) CA3160364C (cg-RX-API-DMAC7.html)
CL (1) CL2022001302A1 (cg-RX-API-DMAC7.html)
IL (1) IL292919B1 (cg-RX-API-DMAC7.html)
MX (1) MX2022005914A (cg-RX-API-DMAC7.html)
PH (1) PH12022551224A1 (cg-RX-API-DMAC7.html)
WO (1) WO2021099518A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210061202A (ko) 2019-11-19 2021-05-27 일동제약(주) 벤조나이트릴이 치환된 축합 피리미딘 유도체 및 그의 의약 용도

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
DE3169595D1 (en) 1980-11-10 1985-05-02 Gersonde Klaus Method of preparing lipid vesicles by ultrasonic treatment, the use of this method and apparatus for its application
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
DE3218121A1 (de) 1982-05-14 1983-11-17 Leskovar, Peter, Dr.-Ing., 8000 München Arzneimittel zur tumorbehandlung
EP0102324A3 (de) 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
DE3483949D1 (de) 1983-09-26 1991-02-21 Udo Dr Med Ehrenfeld Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
DE3474511D1 (en) 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
AU2935200A (en) 1999-04-30 2000-11-17 Pfizer Products Inc. Compounds for the treatment of obesity
US6660753B2 (en) 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US8829198B2 (en) * 2007-10-31 2014-09-09 Proteotech Inc Compounds, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies
WO2004110351A2 (en) * 2003-05-14 2004-12-23 Anadys Pharmaceuticals, Inc. Heterocyclic compounds for treating hepatitis c virus
DE102008020113A1 (de) * 2008-04-23 2009-10-29 Bayer Schering Pharma Aktiengesellschaft Substituierte Dihydropyrazolone und ihre Verwendung
SI2004155T1 (en) * 2006-03-29 2018-05-31 Wista Laboratories Ltd. Inhibitors of protein aggregation
US20110201686A1 (en) * 2006-06-23 2011-08-18 Yousef Al-Abed Inhibitors of ASS and Synuclein Aggregation
JP4616237B2 (ja) 2006-11-07 2011-01-19 日本電信電話株式会社 シリコン化合物薄膜の形成方法
EP2304366A2 (en) * 2008-05-30 2011-04-06 Foster Wheeler Energia Oy Method of and system for generating power by oxyfuel combustion
EP2687513B1 (en) * 2008-06-09 2020-12-02 Ludwig-Maximilians-Universität München Drugs for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases
TW201120016A (en) 2009-12-08 2011-06-16 Abbott Lab Novel oxadiazole compounds
KR102671166B1 (ko) 2015-12-14 2024-05-31 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. 3,5-디페닐-디아졸 화합물의 수용성 유도체
BR112018068066B1 (pt) * 2016-03-11 2023-11-28 Ac Immune Sa Compostos bicíclicos e seu uso, composição diagnóstica e farmacêutica, misturas, métodos de coleção de dados para diagnóstico, para determinar uma predisposição a, para monitorar transtorno residual e para prever a capacidade de resposta de um paciente sofrendo de transtorno ou anormalidade associado com agregados de alfa-sinucleína, métodos para determinar a quantidade de agregados de alfa-sinucleína e para preparar um composto, kit teste e kit para preparar uma preparação radio farmacêutica
US20210261561A1 (en) 2018-04-23 2021-08-26 Shionogi & Co., Ltd. Bicyclic heterocycle derivatives having selective bace1 inhibitory activity

Similar Documents

Publication Publication Date Title
JP5086809B2 (ja) mPGES−1阻害剤としての2−(フェニルまたはヘテロ環式)−1H−フェナントロ[9,10−d]イミダゾール
WO2022222921A1 (zh) 含哌嗪结构的parp抑制剂、其制备方法及医药用途
DK2748149T5 (en) Pyridazinone compounds and their use as DAAO inhibitors
MX2015004787A (es) Compuestos antiviricos para el virus sincitial respiratorio.
EP3555070A1 (en) Amine-substituted heterocyclic compounds as ehmt2 inhibitors and methods of use thereof
JP2009526037A (ja) トリアゾロピリジン化合物
KR20020067589A (ko) 페닐피페라지닐 유도체
JP2024505732A (ja) ピリドピリミジノン系誘導体及びその製造方法と使用
HUE024989T2 (en) Azaindole derivatives as ABI and SRC protein kinase inhibitors
IL298966A (en) Bicyclic compound and application thereof
JP2023520595A (ja) ピラゾロピリダジノン化合物、その医薬組成物及びその用途
CN120418252A (zh) Malt1抑制剂
WO2023069884A1 (en) Kdm1a inhibitors for the treatment of disease
JP2023502794A5 (cg-RX-API-DMAC7.html)
FR2846329A1 (fr) Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
JP7493207B2 (ja) がんの予防又は治療剤
JP2005530691A (ja) 新規なチロインジシンとその関連プロセス、薬学的組成物および方法
EP1902054A1 (fr) Derives de pyrido[2,3-d]pyrimidine, leur preparation, leur application en therapeutique
JP2018536652A5 (cg-RX-API-DMAC7.html)
JP2021535924A (ja) 新規なチアゾール誘導体及びその薬学的に許容される塩
FR2944792A1 (fr) Derives de 1h-pyrazolo[4,3-c]isoquinoleines, leur preparation et leur application en therapeutique
WO2022228512A1 (zh) 作为Wee-1抑制剂的吡咯并嘧啶衍生物
FR2896246A1 (fr) Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
WO2022171088A1 (zh) 吡唑并[3,4-d]嘧啶-3-酮衍生物
CN108341816A (zh) 一种选择性抑制激酶化合物