JP2023501276A5 - - Google Patents

Info

Publication number
JP2023501276A5
JP2023501276A5 JP2022525603A JP2022525603A JP2023501276A5 JP 2023501276 A5 JP2023501276 A5 JP 2023501276A5 JP 2022525603 A JP2022525603 A JP 2022525603A JP 2022525603 A JP2022525603 A JP 2022525603A JP 2023501276 A5 JP2023501276 A5 JP 2023501276A5
Authority
JP
Japan
Prior art keywords
seq
hla
antigen
bispecific antibody
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022525603A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023501276A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/080763 external-priority patent/WO2021089513A1/en
Publication of JP2023501276A publication Critical patent/JP2023501276A/ja
Publication of JP2023501276A5 publication Critical patent/JP2023501276A5/ja
Pending legal-status Critical Current

Links

JP2022525603A 2019-11-05 2020-11-03 Hla-a2/wt1×cd3二重特異性抗体及びレナリドマイドを使用するがんの治療 Pending JP2023501276A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19207090 2019-11-05
EP19207090.2 2019-11-05
PCT/EP2020/080763 WO2021089513A1 (en) 2019-11-05 2020-11-03 Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and lenalidomide

Publications (2)

Publication Number Publication Date
JP2023501276A JP2023501276A (ja) 2023-01-18
JP2023501276A5 true JP2023501276A5 (https=) 2023-11-13

Family

ID=68468600

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022525603A Pending JP2023501276A (ja) 2019-11-05 2020-11-03 Hla-a2/wt1×cd3二重特異性抗体及びレナリドマイドを使用するがんの治療

Country Status (12)

Country Link
US (1) US20220275093A1 (https=)
EP (1) EP4054716A1 (https=)
JP (1) JP2023501276A (https=)
KR (1) KR20220093323A (https=)
CN (1) CN115003384A (https=)
AU (1) AU2020381349A1 (https=)
BR (1) BR112022008652A2 (https=)
CA (1) CA3155308A1 (https=)
IL (1) IL292103A (https=)
MX (1) MX2022005238A (https=)
TW (1) TW202132341A (https=)
WO (1) WO2021089513A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4426735A1 (en) * 2021-11-01 2024-09-11 F. Hoffmann-La Roche AG Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and a 4-1bb (cd137) agonist
WO2024149821A1 (en) * 2023-01-13 2024-07-18 F. Hoffmann-La Roche Ag Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and venetoclax/azacitidine
CN121909214A (zh) * 2023-07-31 2026-04-21 玫帝托克斯股份有限公司 一种抗体及包含该抗体的用于治疗免疫疾病的药物组合物
WO2025103425A1 (en) * 2023-11-15 2025-05-22 Concept To Medicine Biotech Co., Ltd. Multispecific antibodies and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
GB9114948D0 (en) 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
FI941572A7 (fi) 1991-10-07 1994-05-27 Oncologix Inc Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
CA2372813A1 (en) 1992-02-06 1993-08-19 L.L. Houston Biosynthetic binding protein for cancer marker
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
US8404716B2 (en) * 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
WO2018081361A1 (en) * 2016-10-28 2018-05-03 Children's Hospital Medical Center Methods and compositions for treatment of myelodyspastic syndromes and/or acute myleoid leukemias
JP7267914B2 (ja) * 2016-11-02 2023-05-02 エンクマフ エスアーエールエル Bcma及びcd3に対する二重特異性抗体、及び多発性骨髄腫を治療するために併用して使用される免疫療法薬
MX2020006119A (es) 2017-12-21 2020-08-24 Hoffmann La Roche Anticuerpos de union a hla-a2/wt1.

Similar Documents

Publication Publication Date Title
JP2023501276A5 (https=)
JP2022551969A5 (https=)
JP2018537966A5 (https=)
JP2021512630A5 (https=)
JP2023085476A5 (https=)
JP2024534545A5 (https=)
FI3749346T3 (fi) Nkg2d-reseptoriin kohdistuvat vasta-aineen vaihtelevan domeenin yhdistelmät
JP2020531438A5 (ja) Nkg2d、cd16、およびhla−eに結合するタンパク質
JP2021522162A5 (https=)
JP2021507698A5 (https=)
US12098203B2 (en) Hetero-dimeric multi-specific antibody format targeting at least CD3 and HSA
JP2019533441A5 (https=)
JP2021534096A5 (https=)
JP2017537896A5 (https=)
JP2019502712A5 (https=)
JP2021521781A5 (https=)
IL302486A (en) Antibodies against the transnephrine receptor with adapted affinity
JP2023554500A5 (https=)
JP2021515793A5 (https=)
JP2023516195A5 (https=)
Acheampong Bispecific antibody (bsAb) construct formats and their application in cancer therapy
RU2023135060A (ru) Антитела, связывающиеся с cd3
RU2021132277A (ru) Триспецифические и/или тривалентные связывающие белки с применением кроссоверного формата с двойным вариабельным доменом (codv) для лечения инфекции, вызванной hiv
JP2024543942A5 (https=)
JP2022028645A5 (https=)