JP2023169897A5 - - Google Patents
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- JP2023169897A5 JP2023169897A5 JP2023155533A JP2023155533A JP2023169897A5 JP 2023169897 A5 JP2023169897 A5 JP 2023169897A5 JP 2023155533 A JP2023155533 A JP 2023155533A JP 2023155533 A JP2023155533 A JP 2023155533A JP 2023169897 A5 JP2023169897 A5 JP 2023169897A5
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- JP
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- Prior art keywords
- polypeptide
- cell
- seq
- sequence
- cms1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920001184 polypeptide Polymers 0.000 claims 31
- 108090000765 processed proteins & peptides Proteins 0.000 claims 31
- 102000004196 processed proteins & peptides Human genes 0.000 claims 31
- 210000004027 cell Anatomy 0.000 claims 21
- 108091033319 polynucleotide Proteins 0.000 claims 18
- 102000040430 polynucleotide Human genes 0.000 claims 18
- 239000002157 polynucleotide Substances 0.000 claims 18
- 230000000694 effects Effects 0.000 claims 12
- 125000003729 nucleotide group Chemical group 0.000 claims 12
- 102000004533 Endonucleases Human genes 0.000 claims 10
- 108010042407 Endonucleases Proteins 0.000 claims 10
- 108020005004 Guide RNA Proteins 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 239000002773 nucleotide Substances 0.000 claims 8
- 210000004102 animal cell Anatomy 0.000 claims 7
- 230000002538 fungal effect Effects 0.000 claims 5
- 210000001236 prokaryotic cell Anatomy 0.000 claims 5
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 3
- 102000004389 Ribonucleoproteins Human genes 0.000 claims 3
- 108010081734 Ribonucleoproteins Proteins 0.000 claims 3
- 230000035772 mutation Effects 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 101710163270 Nuclease Proteins 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 108020001507 fusion proteins Proteins 0.000 claims 2
- 102000037865 fusion proteins Human genes 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 230000002438 mitochondrial effect Effects 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102100025169 Max-binding protein MNT Human genes 0.000 claims 1
- 108010077850 Nuclear Localization Signals Proteins 0.000 claims 1
- 230000004570 RNA-binding Effects 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 230000004049 epigenetic modification Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- 210000002706 plastid Anatomy 0.000 claims 1
- 230000029279 positive regulation of transcription, DNA-dependent Effects 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
- 108091006107 transcriptional repressors Proteins 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025152643A JP2025185269A (ja) | 2017-08-09 | 2025-09-12 | ゲノムを修飾するための組成物及び方法 |
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762542983P | 2017-08-09 | 2017-08-09 | |
| US62/542,983 | 2017-08-09 | ||
| US201762551958P | 2017-08-30 | 2017-08-30 | |
| US62/551,958 | 2017-08-30 | ||
| US201762565255P | 2017-09-29 | 2017-09-29 | |
| US62/565,255 | 2017-09-29 | ||
| US201762599226P | 2017-12-15 | 2017-12-15 | |
| US62/599,226 | 2017-12-15 | ||
| PCT/IB2018/055972 WO2019030695A1 (en) | 2017-08-09 | 2018-08-08 | Compositions and methods for modifying genomes |
| JP2020507102A JP7355730B2 (ja) | 2017-08-09 | 2018-08-08 | ゲノムを修飾するための組成物及び方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507102A Division JP7355730B2 (ja) | 2017-08-09 | 2018-08-08 | ゲノムを修飾するための組成物及び方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025152643A Division JP2025185269A (ja) | 2017-08-09 | 2025-09-12 | ゲノムを修飾するための組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023169897A JP2023169897A (ja) | 2023-11-30 |
| JP2023169897A5 true JP2023169897A5 (https=) | 2024-06-06 |
Family
ID=63592761
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507102A Active JP7355730B2 (ja) | 2017-08-09 | 2018-08-08 | ゲノムを修飾するための組成物及び方法 |
| JP2023155533A Pending JP2023169897A (ja) | 2017-08-09 | 2023-09-21 | ゲノムを修飾するための組成物及び方法 |
| JP2025152643A Pending JP2025185269A (ja) | 2017-08-09 | 2025-09-12 | ゲノムを修飾するための組成物及び方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507102A Active JP7355730B2 (ja) | 2017-08-09 | 2018-08-08 | ゲノムを修飾するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025152643A Pending JP2025185269A (ja) | 2017-08-09 | 2025-09-12 | ゲノムを修飾するための組成物及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US10316324B2 (https=) |
| EP (3) | EP3665279B1 (https=) |
| JP (3) | JP7355730B2 (https=) |
| KR (3) | KR20250050118A (https=) |
| CN (2) | CN111373040B (https=) |
| AU (2) | AU2018315731B2 (https=) |
| BR (1) | BR112020002647A2 (https=) |
| CA (2) | CA3072312C (https=) |
| ES (1) | ES2960390T3 (https=) |
| IL (2) | IL310452A (https=) |
| WO (1) | WO2019030695A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10337051B2 (en) | 2016-06-16 | 2019-07-02 | The Regents Of The University Of California | Methods and compositions for detecting a target RNA |
| CA3038960A1 (en) | 2016-09-30 | 2018-04-05 | The Regents Of The University Of California | Rna-guided nucleic acid modifying enzymes and methods of use thereof |
| JP7306696B2 (ja) | 2016-09-30 | 2023-07-11 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Ｒｎａ誘導型核酸修飾酵素及びその使用方法 |
| JP7355730B2 (ja) * | 2017-08-09 | 2023-10-03 | ベンソン ヒル，インコーポレイティド | ゲノムを修飾するための組成物及び方法 |
| CN111263810A (zh) | 2017-08-22 | 2020-06-09 | 纳匹基因公司 | 使用多核苷酸指导的核酸内切酶的细胞器基因组修饰 |
| JP2021503278A (ja) | 2017-11-01 | 2021-02-12 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ＣａｓＺ組成物及び使用方法 |
| WO2019089808A1 (en) | 2017-11-01 | 2019-05-09 | The Regents Of The University Of California | Class 2 crispr/cas compositions and methods of use |
| WO2019089804A1 (en) | 2017-11-01 | 2019-05-09 | The Regents Of The University Of California | Casy compositions and methods of use |
| EP3830301B1 (en) | 2018-08-01 | 2024-05-22 | Mammoth Biosciences, Inc. | Programmable nuclease compositions and methods of use thereof |
| US11407995B1 (en) * | 2018-10-26 | 2022-08-09 | Inari Agriculture Technology, Inc. | RNA-guided nucleases and DNA binding proteins |
| EP3931313A2 (en) | 2019-01-04 | 2022-01-05 | Mammoth Biosciences, Inc. | Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection |
| US20230002761A1 (en) * | 2019-11-19 | 2023-01-05 | Benson Hill, Inc. | Anti-bacterial crispr compositions and methods |
| CN111100868B (zh) * | 2019-12-17 | 2021-05-25 | 南京林业大学 | 美洲黑杨的促雌基因ferr和抑雌基因ferr-r及其应用 |
| EP3878958A1 (en) | 2020-03-11 | 2021-09-15 | B.R.A.I.N. Biotechnology Research And Information Network AG | Crispr-cas nucleases from cpr-enriched metagenome |
| EP4159853A4 (en) * | 2020-05-28 | 2023-11-15 | ShanghaiTech University | GENOME EDITING SYSTEM AND METHOD |
| CN113930413B (zh) * | 2020-06-29 | 2024-12-27 | 中国农业大学 | 新型CRISPR-Cas12j.23酶和系统 |
| CN113930411A (zh) * | 2020-06-29 | 2022-01-14 | 中国农业大学 | 新型CRISPR-Cas12M酶和系统 |
| EP3943600A1 (en) | 2020-07-21 | 2022-01-26 | B.R.A.I.N. Biotechnology Research And Information Network AG | Novel, non-naturally occurring crispr-cas nucleases for genome editing |
| US20240376451A1 (en) * | 2021-01-07 | 2024-11-14 | Inscripta, Inc. | Mad nucleases |
| IL305545A (en) | 2021-03-02 | 2023-10-01 | BRAIN Biotech AG | Novel CRISPR-CAS nucleases from metagenomics |
| US20220389418A1 (en) * | 2021-06-01 | 2022-12-08 | Helmholtz-Institut Für Rna-Basierte Nfektionsforschung (Hzi) | Rna-guided cas nucleases and uses thereof in diagnostics and therapy |
| EP4215611A1 (en) | 2022-01-19 | 2023-07-26 | BRAIN Biotech AG | Modification of the genome of a filamentous fungus |
| EP4466347A1 (en) * | 2022-01-19 | 2024-11-27 | BRAIN Biotech AG | Depletion of cells by crispr nucleases |
| EP4215612A1 (en) * | 2022-01-20 | 2023-07-26 | Sartorius Stedim Cellca GmbH | Genome editing with crispr/cas nucleases comprising collateral activity |
| CN115588463B (zh) * | 2022-10-26 | 2025-08-08 | 杭州师范大学 | 基于深度学习挖掘蛋白质相互作用类型的预测方法 |
| EP4361265A1 (en) * | 2022-10-27 | 2024-05-01 | BRAIN Biotech AG | Optimization of editing efficacy of crispr nucleases with collateral activity |
| EP4646475A1 (en) * | 2023-01-04 | 2025-11-12 | BRAIN Biotech AG | Activated bec nucleases for degrading nucleic acid molecules |
| US20260085302A1 (en) | 2024-09-20 | 2026-03-26 | Confluence Genetics, Llc | Compositions and methods for controlling plant pests |
| CN119246486B (zh) * | 2024-12-06 | 2025-04-01 | 南京师范大学 | 一种Cas蛋白在食用油鉴别中的应用 |
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2018
- 2018-08-08 JP JP2020507102A patent/JP7355730B2/ja active Active
- 2018-08-08 KR KR1020257010200A patent/KR20250050118A/ko active Pending
- 2018-08-08 AU AU2018315731A patent/AU2018315731B2/en active Active
- 2018-08-08 CA CA3072312A patent/CA3072312C/en active Active
- 2018-08-08 IL IL310452A patent/IL310452A/en unknown
- 2018-08-08 CN CN201880065634.1A patent/CN111373040B/zh active Active
- 2018-08-08 CN CN202410204271.2A patent/CN118497198A/zh active Pending
- 2018-08-08 BR BR112020002647-6A patent/BR112020002647A2/pt unknown
- 2018-08-08 EP EP18770076.0A patent/EP3665279B1/en active Active
- 2018-08-08 EP EP23186160.0A patent/EP4317443A3/en active Pending
- 2018-08-08 CA CA3284730A patent/CA3284730A1/en active Pending
- 2018-08-08 US US16/058,718 patent/US10316324B2/en active Active
- 2018-08-08 KR KR1020207006387A patent/KR102631985B1/ko active Active
- 2018-08-08 ES ES18770076T patent/ES2960390T3/es active Active
- 2018-08-08 KR KR1020247003280A patent/KR102789904B1/ko active Active
- 2018-08-08 WO PCT/IB2018/055972 patent/WO2019030695A1/en not_active Ceased
- 2018-08-08 IL IL272514A patent/IL272514B2/en unknown
- 2018-08-08 EP EP24171775.0A patent/EP4407034A3/en active Pending
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2019
- 2019-04-24 US US16/393,062 patent/US10837023B2/en active Active
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2020
- 2020-09-29 US US17/037,040 patent/US11624070B2/en active Active
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2023
- 2023-03-03 US US18/177,951 patent/US12146141B2/en active Active
- 2023-09-21 JP JP2023155533A patent/JP2023169897A/ja active Pending
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